| Full name: SERTA domain containing 2 | Alias Symbol: TRIP-Br2|KIAA0127|Sei-2 | ||
| Type: protein-coding gene | Cytoband: 2p14 | ||
| Entrez ID: 9792 | HGNC ID: HGNC:30784 | Ensembl Gene: ENSG00000179833 | OMIM ID: 617851 |
| Drug and gene relationship at DGIdb | |||
Expression of SERTAD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SERTAD2 | 9792 | 202656_s_at | 0.0326 | 0.9548 | |
| GSE20347 | SERTAD2 | 9792 | 202656_s_at | -0.4845 | 0.0067 | |
| GSE23400 | SERTAD2 | 9792 | 202656_s_at | -0.5101 | 0.0000 | |
| GSE26886 | SERTAD2 | 9792 | 202656_s_at | -1.2159 | 0.0000 | |
| GSE29001 | SERTAD2 | 9792 | 202656_s_at | -0.8386 | 0.0198 | |
| GSE38129 | SERTAD2 | 9792 | 202656_s_at | -0.2716 | 0.2201 | |
| GSE45670 | SERTAD2 | 9792 | 202656_s_at | -0.0272 | 0.8915 | |
| GSE53622 | SERTAD2 | 9792 | 23515 | -0.4798 | 0.0000 | |
| GSE53624 | SERTAD2 | 9792 | 23515 | -0.7042 | 0.0000 | |
| GSE63941 | SERTAD2 | 9792 | 202656_s_at | -0.1540 | 0.7731 | |
| GSE77861 | SERTAD2 | 9792 | 202657_s_at | -0.0661 | 0.8755 | |
| GSE97050 | SERTAD2 | 9792 | A_24_P294124 | -0.3090 | 0.2630 | |
| SRP007169 | SERTAD2 | 9792 | RNAseq | -1.9256 | 0.0000 | |
| SRP008496 | SERTAD2 | 9792 | RNAseq | -1.7056 | 0.0000 | |
| SRP064894 | SERTAD2 | 9792 | RNAseq | -0.9430 | 0.0000 | |
| SRP133303 | SERTAD2 | 9792 | RNAseq | -0.0907 | 0.7129 | |
| SRP159526 | SERTAD2 | 9792 | RNAseq | -0.4553 | 0.0413 | |
| SRP193095 | SERTAD2 | 9792 | RNAseq | -1.0362 | 0.0000 | |
| SRP219564 | SERTAD2 | 9792 | RNAseq | -0.7123 | 0.2088 | |
| TCGA | SERTAD2 | 9792 | RNAseq | 0.2110 | 0.0015 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by SERTAD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SERTAD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SERTAD2 | 9792 | 12 | 0 | 18 | |
| GSE20123 | SERTAD2 | 9792 | 12 | 0 | 18 | |
| GSE43470 | SERTAD2 | 9792 | 6 | 0 | 37 | |
| GSE46452 | SERTAD2 | 9792 | 2 | 3 | 54 | |
| GSE47630 | SERTAD2 | 9792 | 8 | 0 | 32 | |
| GSE54993 | SERTAD2 | 9792 | 0 | 6 | 64 | |
| GSE54994 | SERTAD2 | 9792 | 12 | 0 | 41 | |
| GSE60625 | SERTAD2 | 9792 | 0 | 3 | 8 | |
| GSE74703 | SERTAD2 | 9792 | 6 | 0 | 30 | |
| GSE74704 | SERTAD2 | 9792 | 10 | 0 | 10 | |
| TCGA | SERTAD2 | 9792 | 36 | 2 | 58 |
Total number of gains: 104; Total number of losses: 14; Total Number of normals: 370.
Somatic mutations of SERTAD2:
Generating mutation plots.
Highly correlated genes for SERTAD2:
Showing top 20/1048 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SERTAD2 | NUAK2 | 0.776099 | 3 | 0 | 3 |
| SERTAD2 | CCNYL1 | 0.771137 | 3 | 0 | 3 |
| SERTAD2 | PPP4R2 | 0.75139 | 3 | 0 | 3 |
| SERTAD2 | CWC25 | 0.742205 | 3 | 0 | 3 |
| SERTAD2 | OPHN1 | 0.738205 | 3 | 0 | 3 |
| SERTAD2 | VPS35 | 0.733258 | 3 | 0 | 3 |
| SERTAD2 | MTPN | 0.728748 | 5 | 0 | 5 |
| SERTAD2 | CAPNS2 | 0.72525 | 3 | 0 | 3 |
| SERTAD2 | DEF8 | 0.725195 | 3 | 0 | 3 |
| SERTAD2 | ANKRD31 | 0.724396 | 4 | 0 | 4 |
| SERTAD2 | ASPG | 0.719054 | 3 | 0 | 3 |
| SERTAD2 | PAIP2 | 0.715851 | 3 | 0 | 3 |
| SERTAD2 | C6orf132 | 0.714758 | 3 | 0 | 3 |
| SERTAD2 | RAB8A | 0.709829 | 3 | 0 | 3 |
| SERTAD2 | VASN | 0.704827 | 5 | 0 | 5 |
| SERTAD2 | MAP4K5 | 0.702429 | 3 | 0 | 3 |
| SERTAD2 | CNFN | 0.70107 | 4 | 0 | 4 |
| SERTAD2 | CERS3 | 0.700884 | 5 | 0 | 5 |
| SERTAD2 | XG | 0.700488 | 5 | 0 | 5 |
| SERTAD2 | CCDC120 | 0.700027 | 3 | 0 | 3 |
For details and further investigation, click here
