| Full name: cornifelin | Alias Symbol: PLAC8L2 | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 84518 | HGNC ID: HGNC:30183 | Ensembl Gene: ENSG00000105427 | OMIM ID: 611764 |
| Drug and gene relationship at DGIdb | |||
Expression of CNFN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CNFN | 84518 | 224329_s_at | -2.7473 | 0.2170 | |
| GSE26886 | CNFN | 84518 | 224329_s_at | -5.7975 | 0.0000 | |
| GSE45670 | CNFN | 84518 | 224329_s_at | -0.9124 | 0.0641 | |
| GSE53622 | CNFN | 84518 | 62616 | -2.5910 | 0.0000 | |
| GSE53624 | CNFN | 84518 | 62616 | -3.2155 | 0.0000 | |
| GSE63941 | CNFN | 84518 | 224329_s_at | 1.1335 | 0.0656 | |
| GSE77861 | CNFN | 84518 | 224329_s_at | -2.6347 | 0.0094 | |
| GSE97050 | CNFN | 84518 | A_33_P3411848 | -1.4013 | 0.1862 | |
| SRP007169 | CNFN | 84518 | RNAseq | -8.3660 | 0.0000 | |
| SRP008496 | CNFN | 84518 | RNAseq | -6.7168 | 0.0000 | |
| SRP064894 | CNFN | 84518 | RNAseq | -3.7314 | 0.0000 | |
| SRP133303 | CNFN | 84518 | RNAseq | -5.3354 | 0.0000 | |
| SRP159526 | CNFN | 84518 | RNAseq | -5.2418 | 0.0000 | |
| SRP219564 | CNFN | 84518 | RNAseq | -4.6805 | 0.0003 | |
| TCGA | CNFN | 84518 | RNAseq | 0.6318 | 0.0650 |
Upregulated datasets: 0; Downregulated datasets: 10.
Survival by CNFN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CNFN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CNFN | 84518 | 4 | 5 | 21 | |
| GSE20123 | CNFN | 84518 | 4 | 4 | 22 | |
| GSE43470 | CNFN | 84518 | 5 | 11 | 27 | |
| GSE46452 | CNFN | 84518 | 47 | 1 | 11 | |
| GSE47630 | CNFN | 84518 | 8 | 6 | 26 | |
| GSE54993 | CNFN | 84518 | 17 | 4 | 49 | |
| GSE54994 | CNFN | 84518 | 7 | 12 | 34 | |
| GSE60625 | CNFN | 84518 | 9 | 0 | 2 | |
| GSE74703 | CNFN | 84518 | 5 | 7 | 24 | |
| GSE74704 | CNFN | 84518 | 4 | 2 | 14 | |
| TCGA | CNFN | 84518 | 13 | 16 | 67 |
Total number of gains: 123; Total number of losses: 68; Total Number of normals: 297.
Somatic mutations of CNFN:
Generating mutation plots.
Highly correlated genes for CNFN:
Showing top 20/1297 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CNFN | CYSRT1 | 0.925204 | 6 | 0 | 6 |
| CNFN | TMPRSS11E | 0.913015 | 7 | 0 | 7 |
| CNFN | VSIG10L | 0.902506 | 7 | 0 | 7 |
| CNFN | NCCRP1 | 0.901464 | 4 | 0 | 4 |
| CNFN | CSTB | 0.894919 | 8 | 0 | 8 |
| CNFN | CLIC3 | 0.892735 | 6 | 0 | 6 |
| CNFN | SCEL | 0.892388 | 8 | 0 | 8 |
| CNFN | TGM1 | 0.892052 | 8 | 0 | 8 |
| CNFN | RHCG | 0.889867 | 8 | 0 | 8 |
| CNFN | SLURP1 | 0.888267 | 8 | 0 | 8 |
| CNFN | SPRR2F | 0.885192 | 4 | 0 | 4 |
| CNFN | SPRR2E | 0.885022 | 4 | 0 | 4 |
| CNFN | PRSS27 | 0.884227 | 8 | 0 | 8 |
| CNFN | KLK13 | 0.883762 | 8 | 0 | 8 |
| CNFN | A2ML1 | 0.880357 | 8 | 0 | 8 |
| CNFN | TGM3 | 0.879688 | 8 | 0 | 8 |
| CNFN | SPINK5 | 0.878897 | 8 | 0 | 8 |
| CNFN | SBSN | 0.876837 | 8 | 0 | 8 |
| CNFN | CRCT1 | 0.876561 | 9 | 0 | 8 |
| CNFN | EMP1 | 0.873725 | 7 | 0 | 7 |
For details and further investigation, click here
