| Full name: SEC14 and spectrin domain containing 1 | Alias Symbol: DKFZp434O0515|Solo | ||
| Type: protein-coding gene | Cytoband: 2q31.2 | ||
| Entrez ID: 91404 | HGNC ID: HGNC:18379 | Ensembl Gene: ENSG00000187231 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SESTD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SESTD1 | 91404 | 226763_at | -0.0962 | 0.9194 | |
| GSE26886 | SESTD1 | 91404 | 226763_at | 0.6638 | 0.0394 | |
| GSE45670 | SESTD1 | 91404 | 226763_at | -0.7525 | 0.0138 | |
| GSE53622 | SESTD1 | 91404 | 60095 | -0.5199 | 0.0002 | |
| GSE53624 | SESTD1 | 91404 | 60095 | -0.2964 | 0.0103 | |
| GSE63941 | SESTD1 | 91404 | 226763_at | -1.9607 | 0.1192 | |
| GSE77861 | SESTD1 | 91404 | 226763_at | 1.2249 | 0.0036 | |
| GSE97050 | SESTD1 | 91404 | A_33_P3378047 | -0.3247 | 0.5043 | |
| SRP007169 | SESTD1 | 91404 | RNAseq | 1.9681 | 0.0000 | |
| SRP008496 | SESTD1 | 91404 | RNAseq | 1.5125 | 0.0000 | |
| SRP064894 | SESTD1 | 91404 | RNAseq | 0.2316 | 0.4259 | |
| SRP133303 | SESTD1 | 91404 | RNAseq | 0.1399 | 0.5416 | |
| SRP159526 | SESTD1 | 91404 | RNAseq | 0.1887 | 0.4321 | |
| SRP193095 | SESTD1 | 91404 | RNAseq | 0.6255 | 0.0025 | |
| SRP219564 | SESTD1 | 91404 | RNAseq | 0.2577 | 0.6472 | |
| TCGA | SESTD1 | 91404 | RNAseq | -0.2010 | 0.0226 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by SESTD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SESTD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SESTD1 | 91404 | 7 | 0 | 23 | |
| GSE20123 | SESTD1 | 91404 | 7 | 0 | 23 | |
| GSE43470 | SESTD1 | 91404 | 5 | 1 | 37 | |
| GSE46452 | SESTD1 | 91404 | 1 | 4 | 54 | |
| GSE47630 | SESTD1 | 91404 | 4 | 4 | 32 | |
| GSE54993 | SESTD1 | 91404 | 0 | 5 | 65 | |
| GSE54994 | SESTD1 | 91404 | 11 | 5 | 37 | |
| GSE60625 | SESTD1 | 91404 | 0 | 3 | 8 | |
| GSE74703 | SESTD1 | 91404 | 4 | 1 | 31 | |
| GSE74704 | SESTD1 | 91404 | 4 | 0 | 16 | |
| TCGA | SESTD1 | 91404 | 27 | 7 | 62 |
Total number of gains: 70; Total number of losses: 30; Total Number of normals: 388.
Somatic mutations of SESTD1:
Generating mutation plots.
Highly correlated genes for SESTD1:
Showing top 20/622 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SESTD1 | NLK | 0.817158 | 3 | 0 | 3 |
| SESTD1 | TRRAP | 0.803494 | 3 | 0 | 3 |
| SESTD1 | DDIT3 | 0.797501 | 3 | 0 | 3 |
| SESTD1 | WDR81 | 0.789191 | 3 | 0 | 3 |
| SESTD1 | THAP5 | 0.788424 | 3 | 0 | 3 |
| SESTD1 | MFHAS1 | 0.777941 | 3 | 0 | 3 |
| SESTD1 | ZNF260 | 0.777321 | 3 | 0 | 3 |
| SESTD1 | ZBED1 | 0.776166 | 3 | 0 | 3 |
| SESTD1 | FAM50A | 0.76734 | 3 | 0 | 3 |
| SESTD1 | ZNF322 | 0.764905 | 3 | 0 | 3 |
| SESTD1 | ZC3H12C | 0.760756 | 3 | 0 | 3 |
| SESTD1 | C17orf80 | 0.756673 | 3 | 0 | 3 |
| SESTD1 | EMILIN2 | 0.754083 | 3 | 0 | 3 |
| SESTD1 | ULK1 | 0.753875 | 3 | 0 | 3 |
| SESTD1 | DDX42 | 0.746919 | 4 | 0 | 4 |
| SESTD1 | IRF2BP2 | 0.745704 | 4 | 0 | 3 |
| SESTD1 | MSH6 | 0.738229 | 3 | 0 | 3 |
| SESTD1 | HLTF | 0.732025 | 3 | 0 | 3 |
| SESTD1 | CENPV | 0.732008 | 3 | 0 | 3 |
| SESTD1 | PRKRA | 0.729719 | 3 | 0 | 3 |
For details and further investigation, click here
