| Full name: chromosome 17 open reading frame 80 | Alias Symbol: HLC-8|MIG3|FLJ20721|SPEP1 | ||
| Type: protein-coding gene | Cytoband: 17q25.1 | ||
| Entrez ID: 55028 | HGNC ID: HGNC:29601 | Ensembl Gene: ENSG00000141219 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C17orf80:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C17orf80 | 55028 | 223351_at | 0.4754 | 0.3210 | |
| GSE20347 | C17orf80 | 55028 | 221048_x_at | 0.0217 | 0.7127 | |
| GSE23400 | C17orf80 | 55028 | 221048_x_at | -0.0553 | 0.0776 | |
| GSE26886 | C17orf80 | 55028 | 223351_at | 0.1961 | 0.3719 | |
| GSE29001 | C17orf80 | 55028 | 221048_x_at | -0.1475 | 0.2171 | |
| GSE38129 | C17orf80 | 55028 | 221048_x_at | -0.0242 | 0.6975 | |
| GSE45670 | C17orf80 | 55028 | 223351_at | 0.3108 | 0.1250 | |
| GSE53622 | C17orf80 | 55028 | 24053 | 0.4754 | 0.0000 | |
| GSE53624 | C17orf80 | 55028 | 24053 | 0.5997 | 0.0000 | |
| GSE63941 | C17orf80 | 55028 | 223351_at | -0.4845 | 0.1196 | |
| GSE77861 | C17orf80 | 55028 | 223351_at | 0.4056 | 0.0553 | |
| GSE97050 | C17orf80 | 55028 | A_24_P301547 | -0.0397 | 0.8979 | |
| SRP007169 | C17orf80 | 55028 | RNAseq | 0.8396 | 0.0541 | |
| SRP008496 | C17orf80 | 55028 | RNAseq | 0.7943 | 0.0032 | |
| SRP064894 | C17orf80 | 55028 | RNAseq | 0.5787 | 0.0000 | |
| SRP133303 | C17orf80 | 55028 | RNAseq | 0.5322 | 0.0168 | |
| SRP159526 | C17orf80 | 55028 | RNAseq | 0.5612 | 0.0289 | |
| SRP193095 | C17orf80 | 55028 | RNAseq | 0.2008 | 0.0127 | |
| SRP219564 | C17orf80 | 55028 | RNAseq | 1.0818 | 0.1277 | |
| TCGA | C17orf80 | 55028 | RNAseq | -0.0449 | 0.4058 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C17orf80 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C17orf80:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C17orf80 | 55028 | 3 | 2 | 25 | |
| GSE20123 | C17orf80 | 55028 | 3 | 2 | 25 | |
| GSE43470 | C17orf80 | 55028 | 6 | 3 | 34 | |
| GSE46452 | C17orf80 | 55028 | 33 | 0 | 26 | |
| GSE47630 | C17orf80 | 55028 | 8 | 1 | 31 | |
| GSE54993 | C17orf80 | 55028 | 2 | 5 | 63 | |
| GSE54994 | C17orf80 | 55028 | 10 | 4 | 39 | |
| GSE60625 | C17orf80 | 55028 | 6 | 0 | 5 | |
| GSE74703 | C17orf80 | 55028 | 6 | 1 | 29 | |
| GSE74704 | C17orf80 | 55028 | 3 | 2 | 15 | |
| TCGA | C17orf80 | 55028 | 32 | 10 | 54 |
Total number of gains: 112; Total number of losses: 30; Total Number of normals: 346.
Somatic mutations of C17orf80:
Generating mutation plots.
Highly correlated genes for C17orf80:
Showing top 20/672 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C17orf80 | ACACA | 0.804315 | 3 | 0 | 3 |
| C17orf80 | JMY | 0.788225 | 3 | 0 | 3 |
| C17orf80 | DNAJC19 | 0.778379 | 3 | 0 | 3 |
| C17orf80 | KLHL36 | 0.77066 | 3 | 0 | 3 |
| C17orf80 | RAB34 | 0.762886 | 3 | 0 | 3 |
| C17orf80 | SESTD1 | 0.756673 | 3 | 0 | 3 |
| C17orf80 | DCAF7 | 0.74685 | 7 | 0 | 7 |
| C17orf80 | SLC35B2 | 0.744963 | 3 | 0 | 3 |
| C17orf80 | NF1 | 0.737492 | 3 | 0 | 3 |
| C17orf80 | ALKBH6 | 0.736447 | 3 | 0 | 3 |
| C17orf80 | LMBRD2 | 0.734089 | 3 | 0 | 3 |
| C17orf80 | LATS1 | 0.72959 | 4 | 0 | 4 |
| C17orf80 | FAM199X | 0.728841 | 3 | 0 | 3 |
| C17orf80 | DDB1 | 0.725537 | 3 | 0 | 3 |
| C17orf80 | MRPL32 | 0.721875 | 3 | 0 | 3 |
| C17orf80 | HERC2 | 0.717045 | 3 | 0 | 3 |
| C17orf80 | UBR7 | 0.711931 | 4 | 0 | 4 |
| C17orf80 | LSM4 | 0.707296 | 3 | 0 | 3 |
| C17orf80 | FAM49A | 0.705214 | 3 | 0 | 3 |
| C17orf80 | COPRS | 0.700773 | 5 | 0 | 5 |
For details and further investigation, click here
