| Full name: sideroflexin 4 | Alias Symbol: SLC56A4 | ||
| Type: protein-coding gene | Cytoband: 10q26.11 | ||
| Entrez ID: 119559 | HGNC ID: HGNC:16088 | Ensembl Gene: ENSG00000183605 | OMIM ID: 615564 |
| Drug and gene relationship at DGIdb | |||
Expression of SFXN4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SFXN4 | 119559 | 225143_at | 0.3094 | 0.2332 | |
| GSE26886 | SFXN4 | 119559 | 225143_at | -0.0537 | 0.8891 | |
| GSE45670 | SFXN4 | 119559 | 225143_at | 0.3507 | 0.0557 | |
| GSE53622 | SFXN4 | 119559 | 75782 | 0.1445 | 0.0484 | |
| GSE53624 | SFXN4 | 119559 | 75782 | 0.3766 | 0.0000 | |
| GSE63941 | SFXN4 | 119559 | 225143_at | 0.6189 | 0.1830 | |
| GSE77861 | SFXN4 | 119559 | 225143_at | 0.4199 | 0.2059 | |
| GSE97050 | SFXN4 | 119559 | A_23_P75149 | 0.1910 | 0.3445 | |
| SRP007169 | SFXN4 | 119559 | RNAseq | 0.0621 | 0.8971 | |
| SRP064894 | SFXN4 | 119559 | RNAseq | -0.0774 | 0.7154 | |
| SRP133303 | SFXN4 | 119559 | RNAseq | 0.1385 | 0.4068 | |
| SRP159526 | SFXN4 | 119559 | RNAseq | 0.2091 | 0.5131 | |
| SRP193095 | SFXN4 | 119559 | RNAseq | 0.0900 | 0.4905 | |
| SRP219564 | SFXN4 | 119559 | RNAseq | 0.4039 | 0.3779 | |
| TCGA | SFXN4 | 119559 | RNAseq | 0.0772 | 0.2621 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SFXN4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SFXN4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SFXN4 | 119559 | 2 | 8 | 20 | |
| GSE20123 | SFXN4 | 119559 | 2 | 8 | 20 | |
| GSE43470 | SFXN4 | 119559 | 0 | 9 | 34 | |
| GSE46452 | SFXN4 | 119559 | 0 | 11 | 48 | |
| GSE47630 | SFXN4 | 119559 | 2 | 14 | 24 | |
| GSE54993 | SFXN4 | 119559 | 8 | 0 | 62 | |
| GSE54994 | SFXN4 | 119559 | 1 | 9 | 43 | |
| GSE60625 | SFXN4 | 119559 | 0 | 0 | 11 | |
| GSE74703 | SFXN4 | 119559 | 0 | 6 | 30 | |
| GSE74704 | SFXN4 | 119559 | 1 | 3 | 16 | |
| TCGA | SFXN4 | 119559 | 4 | 28 | 64 |
Total number of gains: 20; Total number of losses: 96; Total Number of normals: 372.
Somatic mutations of SFXN4:
Generating mutation plots.
Highly correlated genes for SFXN4:
Showing top 20/493 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SFXN4 | PMS1 | 0.739255 | 3 | 0 | 3 |
| SFXN4 | GNPAT | 0.716129 | 3 | 0 | 3 |
| SFXN4 | TIA1 | 0.714689 | 3 | 0 | 3 |
| SFXN4 | NFKB2 | 0.714053 | 3 | 0 | 3 |
| SFXN4 | DHRSX | 0.708714 | 3 | 0 | 3 |
| SFXN4 | SMARCD2 | 0.700668 | 3 | 0 | 3 |
| SFXN4 | ZNF142 | 0.689914 | 3 | 0 | 3 |
| SFXN4 | IGF2R | 0.68728 | 3 | 0 | 3 |
| SFXN4 | NIPA2 | 0.687141 | 4 | 0 | 4 |
| SFXN4 | ASPSCR1 | 0.687063 | 3 | 0 | 3 |
| SFXN4 | MTO1 | 0.68522 | 3 | 0 | 3 |
| SFXN4 | WDR92 | 0.683853 | 4 | 0 | 3 |
| SFXN4 | CCAR1 | 0.682407 | 3 | 0 | 3 |
| SFXN4 | PHIP | 0.680563 | 3 | 0 | 3 |
| SFXN4 | MAGOHB | 0.679493 | 4 | 0 | 4 |
| SFXN4 | TRIB2 | 0.678633 | 3 | 0 | 3 |
| SFXN4 | METAP1D | 0.672318 | 4 | 0 | 4 |
| SFXN4 | TMEM161A | 0.670645 | 4 | 0 | 3 |
| SFXN4 | USP45 | 0.67032 | 3 | 0 | 3 |
| SFXN4 | ZNF384 | 0.66954 | 4 | 0 | 3 |
For details and further investigation, click here
