MAGOHB

 

Full name: mago homolog B, exon junction complex subunit Alias Symbol: FLJ10292|MGN2
Type: protein-coding gene Cytoband: 12p13.2
Entrez ID: 55110 HGNC ID: HGNC:25504 Ensembl Gene: ENSG00000111196 OMIM ID: 
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of MAGOHB:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MAGOHB 55110 218894_s_at 0.8731 0.0753
GSE20347 MAGOHB 55110 218894_s_at 0.6783 0.0003
GSE23400 MAGOHB 55110 218894_s_at 0.4252 0.0000
GSE26886 MAGOHB 55110 218894_s_at 1.0477 0.0003
GSE29001 MAGOHB 55110 218894_s_at 1.1479 0.0046
GSE38129 MAGOHB 55110 218894_s_at 0.8397 0.0000
GSE45670 MAGOHB 55110 218894_s_at 1.1372 0.0000
GSE53622 MAGOHB 55110 22032 0.5566 0.0000
GSE53624 MAGOHB 55110 22032 0.5151 0.0000
GSE63941 MAGOHB 55110 218894_s_at 0.2107 0.6968
GSE77861 MAGOHB 55110 218894_s_at 0.5596 0.0656
GSE97050 MAGOHB 55110 A_23_P2423 0.3389 0.3353
SRP007169 MAGOHB 55110 RNAseq 0.6474 0.1934
SRP008496 MAGOHB 55110 RNAseq 0.8777 0.0105
SRP064894 MAGOHB 55110 RNAseq 0.3286 0.0389
SRP133303 MAGOHB 55110 RNAseq 0.9595 0.0000
SRP159526 MAGOHB 55110 RNAseq 0.7977 0.0019
SRP193095 MAGOHB 55110 RNAseq 0.1888 0.0703
SRP219564 MAGOHB 55110 RNAseq 0.5112 0.0936
TCGA MAGOHB 55110 RNAseq 0.3373 0.0000

Upregulated datasets: 3; Downregulated datasets: 0.  

 

Survival by MAGOHB expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of MAGOHB:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MAGOHB 55110 6 2 22
GSE20123 MAGOHB 55110 6 2 22
GSE43470 MAGOHB 55110 9 3 31
GSE46452 MAGOHB 55110 10 1 48
GSE47630 MAGOHB 55110 14 2 24
GSE54993 MAGOHB 55110 1 10 59
GSE54994 MAGOHB 55110 9 2 42
GSE60625 MAGOHB 55110 0 1 10
GSE74703 MAGOHB 55110 9 2 25
GSE74704 MAGOHB 55110 4 1 15
TCGA MAGOHB 55110 39 6 51

Total number of gains: 107; Total number of losses: 32; Total Number of normals: 349.  

 

Somatic mutations of MAGOHB:

 

Generating mutation plots.

 

Highly correlated genes for MAGOHB:

 

Showing top 20/2035 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MAGOHBSPNS10.860055303
MAGOHBRPS19BP10.809238303
MAGOHBRP90.77964404
MAGOHBZKSCAN50.775471303
MAGOHBLEMD20.772083303
MAGOHBDBF40.7689181009
MAGOHBSDHAF20.754749303
MAGOHBRNF260.753385404
MAGOHBDDIAS0.750013303
MAGOHBWDR40.747636303
MAGOHBIKBIP0.74751303
MAGOHBALG100.747235504
MAGOHBNCAPD20.7445511011
MAGOHBLRRC340.742282303
MAGOHBKRTCAP20.741668303
MAGOHBWBP110.74108711010
MAGOHBEMG10.7388321009
MAGOHBFOXM10.7372191009
MAGOHBSESN30.736696303
MAGOHBPRDM150.73624303

For details and further investigation, click here