USP45

 

Full name: ubiquitin specific peptidase 45 Alias Symbol: MGC14793
Type: protein-coding gene Cytoband: 6q16.2
Entrez ID: 85015 HGNC ID: HGNC:20080 Ensembl Gene: ENSG00000123552 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of USP45:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 USP45 85015 238057_at -0.1003 0.8357
GSE26886 USP45 85015 224441_s_at -0.7003 0.0015
GSE45670 USP45 85015 238057_at 0.0611 0.8023
GSE53622 USP45 85015 22724 0.1611 0.0239
GSE53624 USP45 85015 22724 0.2624 0.0000
GSE63941 USP45 85015 224441_s_at -0.1684 0.7731
GSE77861 USP45 85015 238057_at 0.4015 0.0702
GSE97050 USP45 85015 A_33_P3289996 0.2185 0.5174
SRP007169 USP45 85015 RNAseq 0.4324 0.3043
SRP008496 USP45 85015 RNAseq 0.3215 0.2557
SRP064894 USP45 85015 RNAseq 0.1233 0.5734
SRP133303 USP45 85015 RNAseq 0.0913 0.4987
SRP159526 USP45 85015 RNAseq 0.2884 0.2977
SRP193095 USP45 85015 RNAseq -0.0809 0.2442
SRP219564 USP45 85015 RNAseq 0.1694 0.5691
TCGA USP45 85015 RNAseq -0.1225 0.0497

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by USP45 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of USP45:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 USP45 85015 2 3 25
GSE20123 USP45 85015 2 2 26
GSE43470 USP45 85015 3 0 40
GSE46452 USP45 85015 2 11 46
GSE47630 USP45 85015 8 6 26
GSE54993 USP45 85015 3 2 65
GSE54994 USP45 85015 8 8 37
GSE60625 USP45 85015 0 1 10
GSE74703 USP45 85015 2 0 34
GSE74704 USP45 85015 1 0 19
TCGA USP45 85015 7 24 65

Total number of gains: 38; Total number of losses: 57; Total Number of normals: 393.  

 

Somatic mutations of USP45:

 

Generating mutation plots.

 

Highly correlated genes for USP45:

 

Showing top 20/92 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
USP45NUFIP20.787051303
USP45SLC35A10.759052303
USP45TMEM980.757206303
USP45CLN80.756564404
USP45AASDHPPT0.734566303
USP45ARL5B0.733868303
USP45SLC6A150.727995303
USP45MDM40.724049303
USP45RNF1110.723009303
USP45STX160.720234303
USP45RELL10.704799303
USP45EXOC20.704267303
USP45CCDC840.703705303
USP45SMARCA50.701406403
USP45CUL50.698511303
USP45PCSK10.697331303
USP45METTL140.696302303
USP45WWP10.695765303
USP45PNP0.691917303
USP45RAB210.69158303

For details and further investigation, click here