| Full name: SHC binding and spindle associated 1 like | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q25.3 | ||
| Entrez ID: 81626 | HGNC ID: HGNC:16788 | Ensembl Gene: ENSG00000157060 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of SHCBP1L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SHCBP1L | 81626 | 220996_s_at | -0.1355 | 0.5325 | |
| GSE20347 | SHCBP1L | 81626 | 220996_s_at | -0.0386 | 0.5365 | |
| GSE23400 | SHCBP1L | 81626 | 220996_s_at | -0.0343 | 0.1732 | |
| GSE26886 | SHCBP1L | 81626 | 220996_s_at | -0.2168 | 0.0111 | |
| GSE29001 | SHCBP1L | 81626 | 220996_s_at | -0.1642 | 0.1720 | |
| GSE38129 | SHCBP1L | 81626 | 220996_s_at | -0.1339 | 0.0222 | |
| GSE45670 | SHCBP1L | 81626 | 220996_s_at | -0.0391 | 0.7065 | |
| GSE53622 | SHCBP1L | 81626 | 53471 | -0.4425 | 0.0009 | |
| GSE53624 | SHCBP1L | 81626 | 53471 | -0.0799 | 0.2683 | |
| GSE63941 | SHCBP1L | 81626 | 220996_s_at | 0.1478 | 0.1715 | |
| GSE77861 | SHCBP1L | 81626 | 220996_s_at | -0.0541 | 0.5285 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SHCBP1L expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of SHCBP1L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SHCBP1L | 81626 | 12 | 0 | 18 | |
| GSE20123 | SHCBP1L | 81626 | 12 | 0 | 18 | |
| GSE43470 | SHCBP1L | 81626 | 7 | 1 | 35 | |
| GSE46452 | SHCBP1L | 81626 | 3 | 1 | 55 | |
| GSE47630 | SHCBP1L | 81626 | 14 | 0 | 26 | |
| GSE54993 | SHCBP1L | 81626 | 0 | 6 | 64 | |
| GSE54994 | SHCBP1L | 81626 | 15 | 0 | 38 | |
| GSE60625 | SHCBP1L | 81626 | 0 | 0 | 11 | |
| GSE74703 | SHCBP1L | 81626 | 7 | 1 | 28 | |
| GSE74704 | SHCBP1L | 81626 | 5 | 0 | 15 | |
| TCGA | SHCBP1L | 81626 | 40 | 3 | 53 |
Total number of gains: 115; Total number of losses: 12; Total Number of normals: 361.
Somatic mutations of SHCBP1L:
Generating mutation plots.
Highly correlated genes for SHCBP1L:
Showing top 20/559 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SHCBP1L | SHOX | 0.728736 | 4 | 0 | 4 |
| SHCBP1L | GRPR | 0.698419 | 4 | 0 | 4 |
| SHCBP1L | TAAR2 | 0.673866 | 4 | 0 | 3 |
| SHCBP1L | NPY5R | 0.673674 | 3 | 0 | 3 |
| SHCBP1L | CETN1 | 0.660249 | 3 | 0 | 3 |
| SHCBP1L | PDX1 | 0.658929 | 4 | 0 | 3 |
| SHCBP1L | PDC | 0.647107 | 4 | 0 | 4 |
| SHCBP1L | CD1B | 0.645654 | 5 | 0 | 5 |
| SHCBP1L | KRTAP5-8 | 0.645289 | 5 | 0 | 5 |
| SHCBP1L | KCNG1 | 0.644019 | 4 | 0 | 3 |
| SHCBP1L | DBH | 0.642035 | 3 | 0 | 3 |
| SHCBP1L | MSI1 | 0.641026 | 5 | 0 | 4 |
| SHCBP1L | NCAN | 0.639785 | 4 | 0 | 4 |
| SHCBP1L | FNDC8 | 0.638833 | 5 | 0 | 5 |
| SHCBP1L | XPNPEP2 | 0.634324 | 5 | 0 | 4 |
| SHCBP1L | AQP6 | 0.632649 | 5 | 0 | 4 |
| SHCBP1L | SRPK3 | 0.631209 | 4 | 0 | 3 |
| SHCBP1L | MYBPH | 0.628124 | 3 | 0 | 3 |
| SHCBP1L | PSG7 | 0.626775 | 3 | 0 | 3 |
| SHCBP1L | SERPIND1 | 0.625468 | 4 | 0 | 3 |
For details and further investigation, click here
