| Full name: potassium voltage-gated channel modifier subfamily G member 1 | Alias Symbol: Kv6.1|kH2|K13 | ||
| Type: protein-coding gene | Cytoband: 20q13.13 | ||
| Entrez ID: 3755 | HGNC ID: HGNC:6248 | Ensembl Gene: ENSG00000026559 | OMIM ID: 603788 |
| Drug and gene relationship at DGIdb | |||
Expression of KCNG1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KCNG1 | 3755 | 211053_at | -0.0528 | 0.8100 | |
| GSE20347 | KCNG1 | 3755 | 214595_at | 0.0937 | 0.7655 | |
| GSE23400 | KCNG1 | 3755 | 211053_at | -0.0287 | 0.4323 | |
| GSE26886 | KCNG1 | 3755 | 211053_at | 0.2290 | 0.0474 | |
| GSE29001 | KCNG1 | 3755 | 211053_at | -0.0233 | 0.9109 | |
| GSE38129 | KCNG1 | 3755 | 214595_at | 0.3098 | 0.2236 | |
| GSE45670 | KCNG1 | 3755 | 214595_at | 0.3563 | 0.2055 | |
| GSE53622 | KCNG1 | 3755 | 78181 | -0.2898 | 0.2989 | |
| GSE53624 | KCNG1 | 3755 | 78181 | -0.2028 | 0.2002 | |
| GSE63941 | KCNG1 | 3755 | 214595_at | 2.3744 | 0.0646 | |
| GSE77861 | KCNG1 | 3755 | 214595_at | -0.1595 | 0.5013 | |
| GSE97050 | KCNG1 | 3755 | A_23_P210581 | 0.4180 | 0.3332 | |
| SRP007169 | KCNG1 | 3755 | RNAseq | -2.1655 | 0.0068 | |
| SRP064894 | KCNG1 | 3755 | RNAseq | -0.5944 | 0.1090 | |
| SRP133303 | KCNG1 | 3755 | RNAseq | -0.0198 | 0.9644 | |
| SRP159526 | KCNG1 | 3755 | RNAseq | 1.2071 | 0.0925 | |
| SRP219564 | KCNG1 | 3755 | RNAseq | 1.1174 | 0.0383 | |
| TCGA | KCNG1 | 3755 | RNAseq | 1.1915 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by KCNG1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KCNG1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KCNG1 | 3755 | 16 | 2 | 12 | |
| GSE20123 | KCNG1 | 3755 | 16 | 2 | 12 | |
| GSE43470 | KCNG1 | 3755 | 13 | 0 | 30 | |
| GSE46452 | KCNG1 | 3755 | 29 | 0 | 30 | |
| GSE47630 | KCNG1 | 3755 | 24 | 1 | 15 | |
| GSE54993 | KCNG1 | 3755 | 0 | 17 | 53 | |
| GSE54994 | KCNG1 | 3755 | 27 | 0 | 26 | |
| GSE60625 | KCNG1 | 3755 | 0 | 0 | 11 | |
| GSE74703 | KCNG1 | 3755 | 11 | 0 | 25 | |
| GSE74704 | KCNG1 | 3755 | 12 | 0 | 8 | |
| TCGA | KCNG1 | 3755 | 46 | 3 | 47 |
Total number of gains: 194; Total number of losses: 25; Total Number of normals: 269.
Somatic mutations of KCNG1:
Generating mutation plots.
Highly correlated genes for KCNG1:
Showing top 20/167 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KCNG1 | NGEF | 0.685798 | 3 | 0 | 3 |
| KCNG1 | ASIC1 | 0.668471 | 3 | 0 | 3 |
| KCNG1 | NCAN | 0.664237 | 3 | 0 | 3 |
| KCNG1 | GPLD1 | 0.656311 | 4 | 0 | 4 |
| KCNG1 | KIR2DL5A | 0.64875 | 3 | 0 | 3 |
| KCNG1 | STMN4 | 0.647666 | 3 | 0 | 3 |
| KCNG1 | BRS3 | 0.645412 | 4 | 0 | 3 |
| KCNG1 | SHCBP1L | 0.644019 | 4 | 0 | 3 |
| KCNG1 | ARVCF | 0.635551 | 3 | 0 | 3 |
| KCNG1 | KCNJ4 | 0.632492 | 4 | 0 | 3 |
| KCNG1 | NTRK3 | 0.631175 | 3 | 0 | 3 |
| KCNG1 | F11 | 0.631101 | 4 | 0 | 4 |
| KCNG1 | EDA | 0.630947 | 5 | 0 | 4 |
| KCNG1 | ZNF556 | 0.630422 | 3 | 0 | 3 |
| KCNG1 | DLX6 | 0.628811 | 4 | 0 | 4 |
| KCNG1 | LY6H | 0.627942 | 3 | 0 | 3 |
| KCNG1 | PDE11A | 0.627777 | 3 | 0 | 3 |
| KCNG1 | CACNG2 | 0.627319 | 5 | 0 | 4 |
| KCNG1 | RHO | 0.623751 | 3 | 0 | 3 |
| KCNG1 | TFAP4 | 0.619385 | 5 | 0 | 4 |
For details and further investigation, click here
