| Full name: myosin binding protein H | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q32.1 | ||
| Entrez ID: 4608 | HGNC ID: HGNC:7552 | Ensembl Gene: ENSG00000133055 | OMIM ID: 160795 |
| Drug and gene relationship at DGIdb | |||
Expression of MYBPH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MYBPH | 4608 | 206304_at | 0.0497 | 0.8436 | |
| GSE20347 | MYBPH | 4608 | 206304_at | -0.0420 | 0.5861 | |
| GSE23400 | MYBPH | 4608 | 206304_at | -0.0753 | 0.1118 | |
| GSE26886 | MYBPH | 4608 | 206304_at | -0.0167 | 0.8955 | |
| GSE29001 | MYBPH | 4608 | 206304_at | -0.1607 | 0.3179 | |
| GSE38129 | MYBPH | 4608 | 206304_at | -0.1367 | 0.0582 | |
| GSE45670 | MYBPH | 4608 | 206304_at | 0.0316 | 0.7166 | |
| GSE63941 | MYBPH | 4608 | 206304_at | 0.2309 | 0.1025 | |
| GSE77861 | MYBPH | 4608 | 206304_at | -0.0479 | 0.6705 | |
| GSE97050 | MYBPH | 4608 | A_23_P148737 | -0.1309 | 0.5141 | |
| TCGA | MYBPH | 4608 | RNAseq | 2.7432 | 0.0741 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MYBPH expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of MYBPH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MYBPH | 4608 | 11 | 0 | 19 | |
| GSE20123 | MYBPH | 4608 | 11 | 0 | 19 | |
| GSE43470 | MYBPH | 4608 | 6 | 0 | 37 | |
| GSE46452 | MYBPH | 4608 | 3 | 1 | 55 | |
| GSE47630 | MYBPH | 4608 | 14 | 0 | 26 | |
| GSE54993 | MYBPH | 4608 | 0 | 6 | 64 | |
| GSE54994 | MYBPH | 4608 | 15 | 0 | 38 | |
| GSE60625 | MYBPH | 4608 | 0 | 0 | 11 | |
| GSE74703 | MYBPH | 4608 | 6 | 0 | 30 | |
| GSE74704 | MYBPH | 4608 | 5 | 0 | 15 | |
| TCGA | MYBPH | 4608 | 44 | 4 | 48 |
Total number of gains: 115; Total number of losses: 11; Total Number of normals: 362.
Somatic mutations of MYBPH:
Generating mutation plots.
Highly correlated genes for MYBPH:
Showing top 20/1030 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MYBPH | MAGEA8 | 0.795749 | 3 | 0 | 3 |
| MYBPH | PTCRA | 0.785083 | 4 | 0 | 4 |
| MYBPH | SCGN | 0.780401 | 4 | 0 | 4 |
| MYBPH | CCDC81 | 0.769465 | 3 | 0 | 3 |
| MYBPH | FAM189A1 | 0.754275 | 3 | 0 | 3 |
| MYBPH | AICDA | 0.748077 | 3 | 0 | 3 |
| MYBPH | LRSAM1 | 0.747699 | 3 | 0 | 3 |
| MYBPH | ABCC6 | 0.743999 | 4 | 0 | 4 |
| MYBPH | SLC12A3 | 0.734696 | 4 | 0 | 3 |
| MYBPH | CHRD | 0.733931 | 3 | 0 | 3 |
| MYBPH | EXOSC1 | 0.730022 | 3 | 0 | 3 |
| MYBPH | USP49 | 0.729273 | 3 | 0 | 3 |
| MYBPH | SLCO1A2 | 0.729193 | 3 | 0 | 3 |
| MYBPH | SLC5A4 | 0.729084 | 5 | 0 | 4 |
| MYBPH | ADM2 | 0.727918 | 5 | 0 | 5 |
| MYBPH | PTH | 0.723597 | 3 | 0 | 3 |
| MYBPH | IFNA4 | 0.721148 | 5 | 0 | 4 |
| MYBPH | SLC6A5 | 0.718101 | 3 | 0 | 3 |
| MYBPH | AMELY | 0.7177 | 3 | 0 | 3 |
| MYBPH | TFF1 | 0.716541 | 3 | 0 | 3 |
For details and further investigation, click here
