CETN1

 

Full name: centrin 1 Alias Symbol: CEN1
Type: protein-coding gene Cytoband: 18p11.32
Entrez ID: 1068 HGNC ID: HGNC:1866 Ensembl Gene: ENSG00000177143 OMIM ID: 603187
Drug and gene relationship at DGIdb

 

Expression of CETN1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CETN1 1068 207209_at 0.0922 0.6837
GSE20347 CETN1 1068 207209_at 0.0154 0.8579
GSE23400 CETN1 1068 207209_at -0.1215 0.0006
GSE26886 CETN1 1068 207209_at 0.1196 0.2327
GSE29001 CETN1 1068 207209_at -0.2362 0.1751
GSE38129 CETN1 1068 207209_at -0.1723 0.1462
GSE45670 CETN1 1068 207209_at 0.0123 0.9323
GSE63941 CETN1 1068 207209_at 0.2059 0.2583
GSE77861 CETN1 1068 207209_at -0.0719 0.4371

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by CETN1 expression:

 

TCGA

 

Note: Click image to view full size file.  

Copy number change of CETN1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CETN1 1068 6 3 21
GSE20123 CETN1 1068 6 3 21
GSE43470 CETN1 1068 2 4 37
GSE46452 CETN1 1068 4 20 35
GSE47630 CETN1 1068 7 18 15
GSE54993 CETN1 1068 6 3 61
GSE54994 CETN1 1068 11 8 34
GSE60625 CETN1 1068 0 4 7
GSE74703 CETN1 1068 2 2 32
GSE74704 CETN1 1068 4 2 14
TCGA CETN1 1068 35 18 43

Total number of gains: 83; Total number of losses: 85; Total Number of normals: 320.  

 

Somatic mutations of CETN1:

 

Generating mutation plots.

 

Highly correlated genes for CETN1:

 

Showing top 20/870 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CETN1ITGB30.76267303
CETN1MTAP0.738421404
CETN1SLC10A10.723289403
CETN1OVGP10.722387303
CETN1RAI10.717284404
CETN1MYT10.714007404
CETN1HAL0.713822504
CETN1AQP80.711473404
CETN1NMNAT20.710363303
CETN1PAX30.709028303
CETN1CCIN0.707477303
CETN1CHST40.703998403
CETN1MMP80.700008303
CETN1CCL160.699368504
CETN1MAP3K190.699322404
CETN1NPAP10.698068404
CETN1CYP3A40.695683404
CETN1ADAM220.694554404
CETN1GRM60.694498404
CETN1CIITA0.69275404

For details and further investigation, click here