NRSN1

 

Full name: neurensin 1 Alias Symbol: p24
Type: protein-coding gene Cytoband: 6p22.3
Entrez ID: 140767 HGNC ID: HGNC:17881 Ensembl Gene: ENSG00000152954 OMIM ID: 616630
Drug and gene relationship at DGIdb

 

Expression of NRSN1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 NRSN1 140767 239293_at 0.1170 0.7485
GSE26886 NRSN1 140767 239293_at -0.0574 0.6976
GSE45670 NRSN1 140767 239293_at 0.0113 0.9222
GSE53622 NRSN1 140767 77690 0.3673 0.0178
GSE53624 NRSN1 140767 77690 0.4320 0.0025
GSE63941 NRSN1 140767 239293_at 0.0126 0.9456
GSE77861 NRSN1 140767 239293_at -0.0232 0.8054
GSE97050 NRSN1 140767 A_33_P3252228 0.0255 0.9143
TCGA NRSN1 140767 RNAseq -2.7910 0.0047

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by NRSN1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of NRSN1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NRSN1 140767 4 2 24
GSE20123 NRSN1 140767 4 2 24
GSE43470 NRSN1 140767 6 0 37
GSE46452 NRSN1 140767 1 9 49
GSE47630 NRSN1 140767 8 5 27
GSE54993 NRSN1 140767 1 1 68
GSE54994 NRSN1 140767 11 4 38
GSE60625 NRSN1 140767 0 1 10
GSE74703 NRSN1 140767 6 0 30
GSE74704 NRSN1 140767 1 1 18
TCGA NRSN1 140767 17 20 59

Total number of gains: 59; Total number of losses: 45; Total Number of normals: 384.  


 

Somatic mutations of NRSN1:

 

Generating mutation plots.

 

Highly correlated genes for NRSN1:

 

Showing top 20/212 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NRSN1TRIM100.825477303
NRSN1KRTAP4-80.822907303
NRSN1SERPINA100.810117404
NRSN1KRTAP10-120.80846303
NRSN1DEFB108B0.790696303
NRSN1OR2T270.78997303
NRSN1STRC0.773284303
NRSN1PTAFR0.766131303
NRSN1KCNH30.765242303
NRSN1DNAH90.758056303
NRSN1SLC22A110.758041303
NRSN1ASB100.756369303
NRSN1FAM71F10.751336303
NRSN1C8orf740.750254303
NRSN1CHST100.748606303
NRSN1PLA2G2C0.747525303
NRSN1OPN40.745607303
NRSN1PRAMEF50.740426303
NRSN1SLC22A310.737168303
NRSN1PNPLA70.732831303

For details and further investigation, click here