| Full name: sprouty related EVH1 domain containing 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19q13 | ||
| Entrez ID: 399473 | HGNC ID: HGNC:31041 | Ensembl Gene: ENSG00000188766 | OMIM ID: 609293 |
| Drug and gene relationship at DGIdb | |||
Expression of SPRED3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPRED3 | 399473 | 230046_at | 0.0255 | 0.9135 | |
| GSE26886 | SPRED3 | 399473 | 230046_at | 0.3888 | 0.0071 | |
| GSE45670 | SPRED3 | 399473 | 230046_at | -0.0362 | 0.7515 | |
| GSE53622 | SPRED3 | 399473 | 86045 | 0.2524 | 0.0464 | |
| GSE53624 | SPRED3 | 399473 | 86045 | 0.1802 | 0.1138 | |
| GSE63941 | SPRED3 | 399473 | 230046_at | 0.2224 | 0.2286 | |
| GSE77861 | SPRED3 | 399473 | 230046_at | 0.1141 | 0.5079 | |
| GSE97050 | SPRED3 | 399473 | A_33_P3401980 | -0.2178 | 0.3712 | |
| SRP064894 | SPRED3 | 399473 | RNAseq | 1.0699 | 0.0002 | |
| SRP133303 | SPRED3 | 399473 | RNAseq | 0.3568 | 0.0233 | |
| SRP159526 | SPRED3 | 399473 | RNAseq | 1.1974 | 0.0032 | |
| SRP193095 | SPRED3 | 399473 | RNAseq | 0.3612 | 0.0349 | |
| SRP219564 | SPRED3 | 399473 | RNAseq | 0.2961 | 0.4281 | |
| TCGA | SPRED3 | 399473 | RNAseq | 0.6718 | 0.0492 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by SPRED3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SPRED3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPRED3 | 399473 | 7 | 4 | 19 | |
| GSE20123 | SPRED3 | 399473 | 7 | 3 | 20 | |
| GSE43470 | SPRED3 | 399473 | 4 | 10 | 29 | |
| GSE46452 | SPRED3 | 399473 | 47 | 2 | 10 | |
| GSE47630 | SPRED3 | 399473 | 9 | 5 | 26 | |
| GSE54993 | SPRED3 | 399473 | 17 | 3 | 50 | |
| GSE54994 | SPRED3 | 399473 | 6 | 9 | 38 | |
| GSE60625 | SPRED3 | 399473 | 9 | 0 | 2 | |
| GSE74703 | SPRED3 | 399473 | 4 | 6 | 26 | |
| GSE74704 | SPRED3 | 399473 | 7 | 1 | 12 | |
| TCGA | SPRED3 | 399473 | 16 | 15 | 65 |
Total number of gains: 133; Total number of losses: 58; Total Number of normals: 297.
Somatic mutations of SPRED3:
Generating mutation plots.
Highly correlated genes for SPRED3:
Showing top 20/667 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPRED3 | C9orf153 | 0.897733 | 3 | 0 | 3 |
| SPRED3 | YY2 | 0.892747 | 3 | 0 | 3 |
| SPRED3 | RNF180 | 0.884473 | 3 | 0 | 3 |
| SPRED3 | LBX2 | 0.861932 | 3 | 0 | 3 |
| SPRED3 | MRGPRG | 0.85887 | 3 | 0 | 3 |
| SPRED3 | KLF17 | 0.849933 | 3 | 0 | 3 |
| SPRED3 | PRSS38 | 0.846888 | 3 | 0 | 3 |
| SPRED3 | SLC22A7 | 0.838693 | 3 | 0 | 3 |
| SPRED3 | STRC | 0.83477 | 3 | 0 | 3 |
| SPRED3 | LTB4R2 | 0.82847 | 3 | 0 | 3 |
| SPRED3 | SLC22A31 | 0.822543 | 3 | 0 | 3 |
| SPRED3 | C1QL2 | 0.819164 | 3 | 0 | 3 |
| SPRED3 | JAKMIP3 | 0.81368 | 3 | 0 | 3 |
| SPRED3 | ZNF527 | 0.809458 | 5 | 0 | 5 |
| SPRED3 | F2RL3 | 0.806091 | 4 | 0 | 4 |
| SPRED3 | OR10AD1 | 0.799032 | 3 | 0 | 3 |
| SPRED3 | PLA2G2C | 0.797918 | 3 | 0 | 3 |
| SPRED3 | CDR2L | 0.795825 | 3 | 0 | 3 |
| SPRED3 | PTAFR | 0.79471 | 3 | 0 | 3 |
| SPRED3 | TSKS | 0.792124 | 3 | 0 | 3 |
For details and further investigation, click here
