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File: /data/webapp/var/www/html/ESCCdb/application/controllers/Result_pages.php
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Multi-Omics Database of ESCC

 

SLC26A3

 

Full name: solute carrier family 26 member 3 Alias Symbol: 
Type: protein-coding gene Cytoband: 7q22.3-q31.1
Entrez ID: 1811 HGNC ID: HGNC:3018 Ensembl Gene: ENSG00000091138 OMIM ID: 126650
Drug and gene relationship at DGIdb

 

Expression of SLC26A3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SLC26A3 1811 215657_at -0.0334 0.8916
GSE20347 SLC26A3 1811 215657_at 0.0497 0.3780
GSE23400 SLC26A3 1811 215657_at -0.0226 0.2804
GSE26886 SLC26A3 1811 206143_at -0.0224 0.8116
GSE29001 SLC26A3 1811 215657_at -0.0512 0.7708
GSE38129 SLC26A3 1811 215657_at 0.0069 0.9096
GSE45670 SLC26A3 1811 215657_at -0.0314 0.6455
GSE63941 SLC26A3 1811 215657_at 0.0876 0.4538
GSE77861 SLC26A3 1811 215657_at -0.0262 0.7711
TCGA SLC26A3 1811 RNAseq -4.0859 0.0000

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by SLC26A3 expression:

 

TCGA

 

Note: Click image to view full size file.  


Copy number change of SLC26A3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SLC26A3 1811 12 0 18
GSE20123 SLC26A3 1811 12 0 18
GSE43470 SLC26A3 1811 6 2 35
GSE46452 SLC26A3 1811 10 1 48
GSE47630 SLC26A3 1811 8 3 29
GSE54993 SLC26A3 1811 2 9 59
GSE54994 SLC26A3 1811 16 3 34
GSE60625 SLC26A3 1811 0 0 11
GSE74703 SLC26A3 1811 6 2 28
GSE74704 SLC26A3 1811 8 0 12
TCGA SLC26A3 1811 50 10 36

Total number of gains: 130; Total number of losses: 30; Total Number of normals: 328.  


 

Somatic mutations of SLC26A3:

 

Generating mutation plots.

 

Highly correlated genes for SLC26A3:

 

Showing top 20/196 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SLC26A3CCDC300.682483404
SLC26A3GALR10.679023303
SLC26A3PSG60.673628303
SLC26A3IL190.669022403
SLC26A3CTAGE10.647725404
SLC26A3ATG100.643239404
SLC26A3FOLH10.638332404
SLC26A3AKAP50.635143303
SLC26A3CYSLTR20.63163504
SLC26A3GML0.627789404
SLC26A3HAPLN10.627775303
SLC26A3NTNG10.62713403
SLC26A3SOAT20.626669504
SLC26A3KIR2DL20.625063404
SLC26A3GRIA30.621869303
SLC26A3IFNA70.621577504
SLC26A3EDA2R0.617857404
SLC26A3TAS2R130.61028505
SLC26A3RFPL20.60965404
SLC26A3PSG70.609146303

For details and further investigation, click here