| Full name: solute carrier family 39 member 10 | Alias Symbol: KIAA1265|FLJ90515|DKFZp564L2123 | ||
| Type: protein-coding gene | Cytoband: 2q32.3 | ||
| Entrez ID: 57181 | HGNC ID: HGNC:20861 | Ensembl Gene: ENSG00000196950 | OMIM ID: 608733 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SLC39A10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC39A10 | 57181 | 225295_at | 1.1411 | 0.0094 | |
| GSE26886 | SLC39A10 | 57181 | 225295_at | 1.8337 | 0.0000 | |
| GSE45670 | SLC39A10 | 57181 | 225295_at | 0.2428 | 0.4939 | |
| GSE53622 | SLC39A10 | 57181 | 6875 | 1.1805 | 0.0000 | |
| GSE53624 | SLC39A10 | 57181 | 6875 | 0.9922 | 0.0000 | |
| GSE63941 | SLC39A10 | 57181 | 225295_at | -0.1010 | 0.9229 | |
| GSE77861 | SLC39A10 | 57181 | 225295_at | 1.4164 | 0.0582 | |
| GSE97050 | SLC39A10 | 57181 | A_23_P119778 | 0.6123 | 0.1436 | |
| SRP007169 | SLC39A10 | 57181 | RNAseq | 1.5329 | 0.0038 | |
| SRP008496 | SLC39A10 | 57181 | RNAseq | 1.3766 | 0.0000 | |
| SRP064894 | SLC39A10 | 57181 | RNAseq | 0.7902 | 0.0003 | |
| SRP133303 | SLC39A10 | 57181 | RNAseq | 0.8615 | 0.0000 | |
| SRP159526 | SLC39A10 | 57181 | RNAseq | 1.0418 | 0.0004 | |
| SRP193095 | SLC39A10 | 57181 | RNAseq | 0.6934 | 0.0000 | |
| SRP219564 | SLC39A10 | 57181 | RNAseq | 0.4680 | 0.1623 | |
| TCGA | SLC39A10 | 57181 | RNAseq | 0.3358 | 0.0000 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by SLC39A10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC39A10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC39A10 | 57181 | 7 | 3 | 20 | |
| GSE20123 | SLC39A10 | 57181 | 8 | 3 | 19 | |
| GSE43470 | SLC39A10 | 57181 | 3 | 1 | 39 | |
| GSE46452 | SLC39A10 | 57181 | 1 | 4 | 54 | |
| GSE47630 | SLC39A10 | 57181 | 4 | 5 | 31 | |
| GSE54993 | SLC39A10 | 57181 | 0 | 4 | 66 | |
| GSE54994 | SLC39A10 | 57181 | 11 | 7 | 35 | |
| GSE60625 | SLC39A10 | 57181 | 0 | 3 | 8 | |
| GSE74703 | SLC39A10 | 57181 | 2 | 1 | 33 | |
| GSE74704 | SLC39A10 | 57181 | 3 | 2 | 15 | |
| TCGA | SLC39A10 | 57181 | 22 | 9 | 65 |
Total number of gains: 61; Total number of losses: 42; Total Number of normals: 385.
Somatic mutations of SLC39A10:
Generating mutation plots.
Highly correlated genes for SLC39A10:
Showing top 20/1946 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC39A10 | PDP1 | 0.832169 | 3 | 0 | 3 |
| SLC39A10 | CMTM4 | 0.820549 | 3 | 0 | 3 |
| SLC39A10 | RAD54L | 0.813888 | 3 | 0 | 3 |
| SLC39A10 | AGPAT5 | 0.79714 | 3 | 0 | 3 |
| SLC39A10 | ESM1 | 0.795671 | 4 | 0 | 4 |
| SLC39A10 | MMS22L | 0.778346 | 3 | 0 | 3 |
| SLC39A10 | CEP170 | 0.773882 | 3 | 0 | 3 |
| SLC39A10 | TCF7L2 | 0.77263 | 3 | 0 | 3 |
| SLC39A10 | TROAP | 0.765889 | 4 | 0 | 4 |
| SLC39A10 | ZNF451 | 0.762031 | 4 | 0 | 4 |
| SLC39A10 | FOXRED2 | 0.754561 | 3 | 0 | 3 |
| SLC39A10 | LSR | 0.753709 | 3 | 0 | 3 |
| SLC39A10 | KLHL8 | 0.752306 | 3 | 0 | 3 |
| SLC39A10 | ELF4 | 0.751487 | 4 | 0 | 4 |
| SLC39A10 | DNAJC11 | 0.748893 | 3 | 0 | 3 |
| SLC39A10 | MAZ | 0.745071 | 3 | 0 | 3 |
| SLC39A10 | SORL1 | 0.744475 | 3 | 0 | 3 |
| SLC39A10 | SAAL1 | 0.743462 | 4 | 0 | 4 |
| SLC39A10 | NOL9 | 0.743358 | 4 | 0 | 4 |
| SLC39A10 | NPHP4 | 0.743241 | 5 | 0 | 5 |
For details and further investigation, click here
