| Full name: RAD54 like | Alias Symbol: hHR54|hRAD54|RAD54A | ||
| Type: protein-coding gene | Cytoband: 1p34.1 | ||
| Entrez ID: 8438 | HGNC ID: HGNC:9826 | Ensembl Gene: ENSG00000085999 | OMIM ID: 603615 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RAD54L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RAD54L | 8438 | 204558_at | 1.3183 | 0.0498 | |
| GSE20347 | RAD54L | 8438 | 204558_at | 1.3405 | 0.0000 | |
| GSE23400 | RAD54L | 8438 | 204558_at | 0.5576 | 0.0000 | |
| GSE26886 | RAD54L | 8438 | 204558_at | 0.4325 | 0.0245 | |
| GSE29001 | RAD54L | 8438 | 204558_at | 1.0212 | 0.0006 | |
| GSE38129 | RAD54L | 8438 | 204558_at | 1.4120 | 0.0000 | |
| GSE45670 | RAD54L | 8438 | 204558_at | 0.8152 | 0.0002 | |
| GSE63941 | RAD54L | 8438 | 204558_at | 1.0091 | 0.0576 | |
| GSE77861 | RAD54L | 8438 | 204558_at | 0.2628 | 0.0702 | |
| GSE97050 | RAD54L | 8438 | A_23_P74115 | 0.8933 | 0.1657 | |
| SRP007169 | RAD54L | 8438 | RNAseq | 2.5963 | 0.0005 | |
| SRP008496 | RAD54L | 8438 | RNAseq | 1.8139 | 0.0010 | |
| SRP064894 | RAD54L | 8438 | RNAseq | 1.7195 | 0.0000 | |
| SRP133303 | RAD54L | 8438 | RNAseq | 1.1997 | 0.0000 | |
| SRP159526 | RAD54L | 8438 | RNAseq | 2.2521 | 0.0001 | |
| SRP193095 | RAD54L | 8438 | RNAseq | 1.2270 | 0.0000 | |
| SRP219564 | RAD54L | 8438 | RNAseq | 2.2414 | 0.0017 | |
| TCGA | RAD54L | 8438 | RNAseq | 1.5733 | 0.0000 |
Upregulated datasets: 12; Downregulated datasets: 0.
Survival by RAD54L expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of RAD54L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RAD54L | 8438 | 4 | 3 | 23 | |
| GSE20123 | RAD54L | 8438 | 4 | 2 | 24 | |
| GSE43470 | RAD54L | 8438 | 5 | 2 | 36 | |
| GSE46452 | RAD54L | 8438 | 2 | 1 | 56 | |
| GSE47630 | RAD54L | 8438 | 8 | 4 | 28 | |
| GSE54993 | RAD54L | 8438 | 0 | 1 | 69 | |
| GSE54994 | RAD54L | 8438 | 11 | 2 | 40 | |
| GSE60625 | RAD54L | 8438 | 0 | 0 | 11 | |
| GSE74703 | RAD54L | 8438 | 4 | 1 | 31 | |
| GSE74704 | RAD54L | 8438 | 2 | 0 | 18 | |
| TCGA | RAD54L | 8438 | 10 | 17 | 69 |
Total number of gains: 50; Total number of losses: 33; Total Number of normals: 405.
Somatic mutations of RAD54L:
Generating mutation plots.
Highly correlated genes for RAD54L:
Showing top 20/1780 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RAD54L | SLC39A10 | 0.813888 | 3 | 0 | 3 |
| RAD54L | KIF2C | 0.791591 | 11 | 0 | 11 |
| RAD54L | GEN1 | 0.78986 | 3 | 0 | 3 |
| RAD54L | MCM2 | 0.782706 | 9 | 0 | 9 |
| RAD54L | ZBTB9 | 0.774072 | 3 | 0 | 3 |
| RAD54L | SPNS1 | 0.771552 | 3 | 0 | 3 |
| RAD54L | CDCA3 | 0.766208 | 10 | 0 | 10 |
| RAD54L | BUB1 | 0.763579 | 8 | 0 | 8 |
| RAD54L | PRTFDC1 | 0.76351 | 3 | 0 | 3 |
| RAD54L | DNMT1 | 0.761284 | 10 | 0 | 10 |
| RAD54L | C10orf55 | 0.760566 | 3 | 0 | 3 |
| RAD54L | FANCA | 0.75917 | 8 | 0 | 8 |
| RAD54L | MYBL2 | 0.755324 | 10 | 0 | 9 |
| RAD54L | WDHD1 | 0.755137 | 10 | 0 | 10 |
| RAD54L | CDC20 | 0.753817 | 10 | 0 | 10 |
| RAD54L | G2E3 | 0.752252 | 4 | 0 | 4 |
| RAD54L | NCAPH | 0.751958 | 9 | 0 | 9 |
| RAD54L | SIX4 | 0.748089 | 5 | 0 | 5 |
| RAD54L | CCNF | 0.747916 | 10 | 0 | 10 |
| RAD54L | RPF2 | 0.745938 | 3 | 0 | 3 |
For details and further investigation, click here
