| Full name: trophinin associated protein | Alias Symbol: TASTIN | ||
| Type: protein-coding gene | Cytoband: 12q13.12 | ||
| Entrez ID: 10024 | HGNC ID: HGNC:12327 | Ensembl Gene: ENSG00000135451 | OMIM ID: 603872 |
| Drug and gene relationship at DGIdb | |||
Expression of TROAP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TROAP | 10024 | 204649_at | 1.1962 | 0.0240 | |
| GSE20347 | TROAP | 10024 | 204649_at | 0.9300 | 0.0000 | |
| GSE23400 | TROAP | 10024 | 204649_at | 0.6437 | 0.0000 | |
| GSE26886 | TROAP | 10024 | 204649_at | 0.3407 | 0.0838 | |
| GSE29001 | TROAP | 10024 | 204649_at | 0.6767 | 0.0231 | |
| GSE38129 | TROAP | 10024 | 204649_at | 0.9639 | 0.0000 | |
| GSE45670 | TROAP | 10024 | 1568596_a_at | 1.0408 | 0.0002 | |
| GSE53622 | TROAP | 10024 | 66731 | 1.4875 | 0.0000 | |
| GSE53624 | TROAP | 10024 | 66731 | 1.4256 | 0.0000 | |
| GSE63941 | TROAP | 10024 | 1568596_a_at | 1.9864 | 0.0010 | |
| GSE77861 | TROAP | 10024 | 204649_at | 0.3889 | 0.0397 | |
| GSE97050 | TROAP | 10024 | A_23_P150935 | 0.5070 | 0.2276 | |
| SRP007169 | TROAP | 10024 | RNAseq | 2.5330 | 0.0000 | |
| SRP008496 | TROAP | 10024 | RNAseq | 2.1626 | 0.0000 | |
| SRP064894 | TROAP | 10024 | RNAseq | 2.0904 | 0.0000 | |
| SRP133303 | TROAP | 10024 | RNAseq | 1.9054 | 0.0000 | |
| SRP159526 | TROAP | 10024 | RNAseq | 2.5168 | 0.0000 | |
| SRP193095 | TROAP | 10024 | RNAseq | 1.4995 | 0.0000 | |
| SRP219564 | TROAP | 10024 | RNAseq | 1.7237 | 0.0573 | |
| TCGA | TROAP | 10024 | RNAseq | 1.3288 | 0.0000 |
Upregulated datasets: 12; Downregulated datasets: 0.
Survival by TROAP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TROAP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TROAP | 10024 | 6 | 1 | 23 | |
| GSE20123 | TROAP | 10024 | 7 | 1 | 22 | |
| GSE43470 | TROAP | 10024 | 3 | 1 | 39 | |
| GSE46452 | TROAP | 10024 | 8 | 1 | 50 | |
| GSE47630 | TROAP | 10024 | 11 | 2 | 27 | |
| GSE54993 | TROAP | 10024 | 0 | 5 | 65 | |
| GSE54994 | TROAP | 10024 | 4 | 1 | 48 | |
| GSE60625 | TROAP | 10024 | 0 | 0 | 11 | |
| GSE74703 | TROAP | 10024 | 3 | 1 | 32 | |
| GSE74704 | TROAP | 10024 | 5 | 1 | 14 | |
| TCGA | TROAP | 10024 | 16 | 11 | 69 |
Total number of gains: 63; Total number of losses: 25; Total Number of normals: 400.
Somatic mutations of TROAP:
Generating mutation plots.
Highly correlated genes for TROAP:
Showing top 20/1754 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TROAP | KIF18B | 0.811156 | 10 | 0 | 10 |
| TROAP | LRRC58 | 0.805754 | 3 | 0 | 3 |
| TROAP | CCNB2 | 0.805175 | 10 | 0 | 10 |
| TROAP | NUF2 | 0.794974 | 8 | 0 | 8 |
| TROAP | UBE2C | 0.789286 | 12 | 0 | 11 |
| TROAP | MTERF3 | 0.784461 | 6 | 0 | 6 |
| TROAP | CDCA3 | 0.781093 | 11 | 0 | 11 |
| TROAP | DDX39A | 0.78002 | 10 | 0 | 10 |
| TROAP | UBE2T | 0.778931 | 8 | 0 | 7 |
| TROAP | BLM | 0.776511 | 12 | 0 | 12 |
| TROAP | TOP2A | 0.775878 | 12 | 0 | 12 |
| TROAP | CDCA2 | 0.774407 | 6 | 0 | 5 |
| TROAP | CKS1B | 0.771623 | 10 | 0 | 10 |
| TROAP | MTFR2 | 0.771144 | 7 | 0 | 7 |
| TROAP | AURKB | 0.767482 | 11 | 0 | 11 |
| TROAP | SLC39A10 | 0.765889 | 4 | 0 | 4 |
| TROAP | SPAG5 | 0.765562 | 11 | 0 | 11 |
| TROAP | NUSAP1 | 0.765161 | 12 | 0 | 12 |
| TROAP | KIF14 | 0.762374 | 13 | 0 | 12 |
| TROAP | AURKA | 0.761973 | 12 | 0 | 12 |
For details and further investigation, click here
