TRIM9

 

Full name: tripartite motif containing 9 Alias Symbol: SPRING|RNF91
Type: protein-coding gene Cytoband: 14q22.1
Entrez ID: 114088 HGNC ID: HGNC:16288 Ensembl Gene: ENSG00000100505 OMIM ID: 606555
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of TRIM9:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TRIM9 114088 209859_at 1.0633 0.1411
GSE20347 TRIM9 114088 209859_at 0.7024 0.0037
GSE23400 TRIM9 114088 209859_at 0.2021 0.0002
GSE26886 TRIM9 114088 209859_at 1.8809 0.0001
GSE29001 TRIM9 114088 209859_at 0.9233 0.0070
GSE38129 TRIM9 114088 209859_at 0.5501 0.0047
GSE45670 TRIM9 114088 209859_at 0.2425 0.6026
GSE53622 TRIM9 114088 66380 1.1326 0.0000
GSE53624 TRIM9 114088 66380 1.5046 0.0000
GSE63941 TRIM9 114088 209859_at -0.0519 0.9618
GSE77861 TRIM9 114088 209859_at 0.2985 0.2339
GSE97050 TRIM9 114088 A_33_P3383836 0.5980 0.2827
SRP064894 TRIM9 114088 RNAseq 1.6527 0.0001
SRP133303 TRIM9 114088 RNAseq 0.5518 0.2138
SRP159526 TRIM9 114088 RNAseq 1.7305 0.0322
SRP219564 TRIM9 114088 RNAseq 1.2661 0.0140
TCGA TRIM9 114088 RNAseq 0.0096 0.9724

Upregulated datasets: 6; Downregulated datasets: 0.  


 

Survival by TRIM9 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of TRIM9:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TRIM9 114088 8 3 19
GSE20123 TRIM9 114088 8 3 19
GSE43470 TRIM9 114088 9 1 33
GSE46452 TRIM9 114088 16 3 40
GSE47630 TRIM9 114088 11 10 19
GSE54993 TRIM9 114088 3 8 59
GSE54994 TRIM9 114088 19 4 30
GSE60625 TRIM9 114088 0 2 9
GSE74703 TRIM9 114088 8 1 27
GSE74704 TRIM9 114088 3 2 15
TCGA TRIM9 114088 34 13 49

Total number of gains: 119; Total number of losses: 50; Total Number of normals: 319.  


 

Somatic mutations of TRIM9:

 

Generating mutation plots.

 

Highly correlated genes for TRIM9:

 

Showing top 20/348 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TRIM9SLC52A10.753693303
TRIM9YY10.704008303
TRIM9ZNF2840.686868303
TRIM9C1orf530.678881303
TRIM9ASCL20.673407403
TRIM9SS18L10.662744404
TRIM9GMEB20.654868403
TRIM9NACC10.653211303
TRIM9ASAP1-IT10.651694303
TRIM9ZNF5790.650748303
TRIM9CCHCR10.648111403
TRIM9CBX20.647282403
TRIM9CEP1310.644459303
TRIM9PLA2G150.643805403
TRIM9VANGL20.64054303
TRIM9F2R0.638729504
TRIM9KRTCAP20.638419303
TRIM9SEL1L0.63643504
TRIM9ANXA100.633888403
TRIM9TANGO20.630632403

For details and further investigation, click here