SLCO1C1

 

Full name: solute carrier organic anion transporter family member 1C1 Alias Symbol: OATP-F|OATP1C1|OATP1
Type: protein-coding gene Cytoband: 12p12.2
Entrez ID: 53919 HGNC ID: HGNC:13819 Ensembl Gene: ENSG00000139155 OMIM ID: 613389
Drug and gene relationship at DGIdb

 

Expression of SLCO1C1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SLCO1C1 53919 220460_at 0.0458 0.8648
GSE20347 SLCO1C1 53919 220460_at 0.0741 0.1921
GSE23400 SLCO1C1 53919 220460_at -0.0002 0.9955
GSE26886 SLCO1C1 53919 220460_at -0.1421 0.1793
GSE29001 SLCO1C1 53919 220460_at 0.0277 0.9122
GSE38129 SLCO1C1 53919 220460_at -0.0238 0.7763
GSE45670 SLCO1C1 53919 220460_at -0.0080 0.9589
GSE53622 SLCO1C1 53919 153373 -0.4437 0.0016
GSE53624 SLCO1C1 53919 153373 -0.6842 0.0000
GSE63941 SLCO1C1 53919 220460_at -0.1156 0.4847
GSE77861 SLCO1C1 53919 220460_at -0.0376 0.6841
SRP133303 SLCO1C1 53919 RNAseq 0.3442 0.4895
TCGA SLCO1C1 53919 RNAseq -0.6275 0.2329

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by SLCO1C1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of SLCO1C1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SLCO1C1 53919 9 2 19
GSE20123 SLCO1C1 53919 9 2 19
GSE43470 SLCO1C1 53919 9 4 30
GSE46452 SLCO1C1 53919 10 1 48
GSE47630 SLCO1C1 53919 14 1 25
GSE54993 SLCO1C1 53919 1 9 60
GSE54994 SLCO1C1 53919 12 2 39
GSE60625 SLCO1C1 53919 0 1 10
GSE74703 SLCO1C1 53919 9 3 24
GSE74704 SLCO1C1 53919 6 1 13
TCGA SLCO1C1 53919 42 5 49

Total number of gains: 121; Total number of losses: 31; Total Number of normals: 336.  


 

Somatic mutations of SLCO1C1:

 

Generating mutation plots.

 

Highly correlated genes for SLCO1C1:

 

Showing top 20/335 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SLCO1C1KIF5A0.756032404
SLCO1C1OR10C10.727422404
SLCO1C1KIR2DL5A0.720367404
SLCO1C1SLC5A40.720286404
SLCO1C1CHST50.703828404
SLCO1C1NTNG10.702231303
SLCO1C1PRR340.694254303
SLCO1C1LLGL10.691274303
SLCO1C1RRH0.688412303
SLCO1C1NEUROD60.682205404
SLCO1C1RUNX20.68059303
SLCO1C1GDF90.680414303
SLCO1C1CHRM20.678542303
SLCO1C1CDC25C0.669005303
SLCO1C1LUZP40.667975404
SLCO1C1CHRNA60.665964303
SLCO1C1SLC6A120.665336303
SLCO1C1PLIN10.664871404
SLCO1C1CLCN40.664146303
SLCO1C1COLEC100.663048404

For details and further investigation, click here