| Full name: retinal pigment epithelium-derived rhodopsin homolog | Alias Symbol: peropsin | ||
| Type: protein-coding gene | Cytoband: 4q25 | ||
| Entrez ID: 10692 | HGNC ID: HGNC:10450 | Ensembl Gene: ENSG00000180245 | OMIM ID: 605224 |
| Drug and gene relationship at DGIdb | |||
Expression of RRH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RRH | 10692 | 208314_at | 0.0378 | 0.9107 | |
| GSE20347 | RRH | 10692 | 208314_at | 0.0842 | 0.1785 | |
| GSE23400 | RRH | 10692 | 208314_at | -0.0739 | 0.0924 | |
| GSE26886 | RRH | 10692 | 208314_at | 0.0571 | 0.5828 | |
| GSE29001 | RRH | 10692 | 208314_at | -0.0626 | 0.7252 | |
| GSE38129 | RRH | 10692 | 208314_at | 0.0701 | 0.2958 | |
| GSE45670 | RRH | 10692 | 208314_at | 0.0951 | 0.2863 | |
| GSE53622 | RRH | 10692 | 138994 | -0.1110 | 0.3271 | |
| GSE53624 | RRH | 10692 | 138994 | -0.1073 | 0.1848 | |
| GSE63941 | RRH | 10692 | 208314_at | -0.2228 | 0.1336 | |
| GSE77861 | RRH | 10692 | 208314_at | -0.0183 | 0.8607 | |
| GSE97050 | RRH | 10692 | A_23_P253723 | -0.1342 | 0.6159 | |
| TCGA | RRH | 10692 | RNAseq | -0.3817 | 0.5058 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RRH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RRH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RRH | 10692 | 1 | 12 | 17 | |
| GSE20123 | RRH | 10692 | 1 | 12 | 17 | |
| GSE43470 | RRH | 10692 | 0 | 13 | 30 | |
| GSE46452 | RRH | 10692 | 1 | 36 | 22 | |
| GSE47630 | RRH | 10692 | 0 | 20 | 20 | |
| GSE54993 | RRH | 10692 | 9 | 0 | 61 | |
| GSE54994 | RRH | 10692 | 1 | 10 | 42 | |
| GSE60625 | RRH | 10692 | 0 | 3 | 8 | |
| GSE74703 | RRH | 10692 | 0 | 11 | 25 | |
| GSE74704 | RRH | 10692 | 0 | 6 | 14 | |
| TCGA | RRH | 10692 | 8 | 35 | 53 |
Total number of gains: 21; Total number of losses: 158; Total Number of normals: 309.
Somatic mutations of RRH:
Generating mutation plots.
Highly correlated genes for RRH:
Showing top 20/305 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RRH | NTNG1 | 0.717894 | 4 | 0 | 4 |
| RRH | EPOR | 0.704836 | 4 | 0 | 4 |
| RRH | GC | 0.704318 | 4 | 0 | 4 |
| RRH | CBLN1 | 0.70164 | 3 | 0 | 3 |
| RRH | HAND1 | 0.701072 | 4 | 0 | 4 |
| RRH | IL1RAPL2 | 0.691712 | 4 | 0 | 4 |
| RRH | SLCO1C1 | 0.688412 | 3 | 0 | 3 |
| RRH | MYEF2 | 0.686863 | 3 | 0 | 3 |
| RRH | CST8 | 0.685562 | 3 | 0 | 3 |
| RRH | NXPE4 | 0.684927 | 4 | 0 | 4 |
| RRH | KIR2DL5A | 0.682256 | 4 | 0 | 4 |
| RRH | MC2R | 0.681638 | 4 | 0 | 4 |
| RRH | PRLR | 0.676133 | 3 | 0 | 3 |
| RRH | GABRA1 | 0.66785 | 3 | 0 | 3 |
| RRH | HS3ST2 | 0.667552 | 3 | 0 | 3 |
| RRH | ZNF850 | 0.667441 | 3 | 0 | 3 |
| RRH | OR52A1 | 0.666272 | 5 | 0 | 5 |
| RRH | TRHR | 0.663688 | 5 | 0 | 5 |
| RRH | IGFBPL1 | 0.653718 | 3 | 0 | 3 |
| RRH | ATRNL1 | 0.653679 | 3 | 0 | 3 |
For details and further investigation, click here
