| Full name: TNF receptor associated factor 5 | Alias Symbol: RNF84 | ||
| Type: protein-coding gene | Cytoband: 1q32.3 | ||
| Entrez ID: 7188 | HGNC ID: HGNC:12035 | Ensembl Gene: ENSG00000082512 | OMIM ID: 602356 |
| Drug and gene relationship at DGIdb | |||
TRAF5 involved pathways:
Expression of TRAF5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRAF5 | 7188 | 204352_at | 0.0770 | 0.9449 | |
| GSE20347 | TRAF5 | 7188 | 204352_at | 1.0817 | 0.0000 | |
| GSE23400 | TRAF5 | 7188 | 204352_at | 0.2302 | 0.0931 | |
| GSE26886 | TRAF5 | 7188 | 204352_at | 1.9145 | 0.0001 | |
| GSE29001 | TRAF5 | 7188 | 204352_at | 0.9198 | 0.0048 | |
| GSE38129 | TRAF5 | 7188 | 204352_at | 0.4470 | 0.1582 | |
| GSE45670 | TRAF5 | 7188 | 204352_at | -0.6487 | 0.0396 | |
| GSE53622 | TRAF5 | 7188 | 36046 | -0.0224 | 0.8670 | |
| GSE53624 | TRAF5 | 7188 | 36046 | 0.1796 | 0.0433 | |
| GSE63941 | TRAF5 | 7188 | 204352_at | -1.5525 | 0.1116 | |
| GSE77861 | TRAF5 | 7188 | 204352_at | 1.0643 | 0.0670 | |
| GSE97050 | TRAF5 | 7188 | A_23_P201731 | -0.2601 | 0.3653 | |
| SRP007169 | TRAF5 | 7188 | RNAseq | 1.3991 | 0.0330 | |
| SRP008496 | TRAF5 | 7188 | RNAseq | 2.2054 | 0.0000 | |
| SRP064894 | TRAF5 | 7188 | RNAseq | 0.3375 | 0.1494 | |
| SRP133303 | TRAF5 | 7188 | RNAseq | 0.0163 | 0.9351 | |
| SRP159526 | TRAF5 | 7188 | RNAseq | -0.2936 | 0.2808 | |
| SRP193095 | TRAF5 | 7188 | RNAseq | 0.7197 | 0.0033 | |
| SRP219564 | TRAF5 | 7188 | RNAseq | 0.3072 | 0.5500 | |
| TCGA | TRAF5 | 7188 | RNAseq | -0.3296 | 0.0010 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by TRAF5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRAF5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRAF5 | 7188 | 10 | 0 | 20 | |
| GSE20123 | TRAF5 | 7188 | 10 | 0 | 20 | |
| GSE43470 | TRAF5 | 7188 | 7 | 0 | 36 | |
| GSE46452 | TRAF5 | 7188 | 3 | 1 | 55 | |
| GSE47630 | TRAF5 | 7188 | 15 | 0 | 25 | |
| GSE54993 | TRAF5 | 7188 | 0 | 6 | 64 | |
| GSE54994 | TRAF5 | 7188 | 13 | 0 | 40 | |
| GSE60625 | TRAF5 | 7188 | 0 | 0 | 11 | |
| GSE74703 | TRAF5 | 7188 | 7 | 0 | 29 | |
| GSE74704 | TRAF5 | 7188 | 4 | 0 | 16 | |
| TCGA | TRAF5 | 7188 | 45 | 3 | 48 |
Total number of gains: 114; Total number of losses: 10; Total Number of normals: 364.
Somatic mutations of TRAF5:
Generating mutation plots.
Highly correlated genes for TRAF5:
Showing top 20/1306 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRAF5 | C11orf49 | 0.849286 | 3 | 0 | 3 |
| TRAF5 | DNM1L | 0.783906 | 3 | 0 | 3 |
| TRAF5 | NPNT | 0.765544 | 3 | 0 | 3 |
| TRAF5 | PDE7A | 0.752717 | 3 | 0 | 3 |
| TRAF5 | MTERF3 | 0.751228 | 4 | 0 | 4 |
| TRAF5 | THEM4 | 0.739601 | 4 | 0 | 4 |
| TRAF5 | IRF2BP2 | 0.737167 | 3 | 0 | 3 |
| TRAF5 | MRPS26 | 0.734249 | 3 | 0 | 3 |
| TRAF5 | ZNRF3 | 0.725809 | 3 | 0 | 3 |
| TRAF5 | RPL19 | 0.722365 | 3 | 0 | 3 |
| TRAF5 | MED22 | 0.720369 | 4 | 0 | 4 |
| TRAF5 | MYEF2 | 0.719911 | 3 | 0 | 3 |
| TRAF5 | RICTOR | 0.71822 | 4 | 0 | 4 |
| TRAF5 | DCAF17 | 0.717879 | 3 | 0 | 3 |
| TRAF5 | MRPL9 | 0.713498 | 3 | 0 | 3 |
| TRAF5 | WDR81 | 0.710619 | 4 | 0 | 4 |
| TRAF5 | FAM43B | 0.708895 | 3 | 0 | 3 |
| TRAF5 | CTHRC1 | 0.706619 | 3 | 0 | 3 |
| TRAF5 | TUBE1 | 0.705504 | 3 | 0 | 3 |
| TRAF5 | TNFSF12 | 0.702747 | 3 | 0 | 3 |
For details and further investigation, click here
