| Full name: small integral membrane protein 7 | Alias Symbol: MGC2747 | ||
| Type: protein-coding gene | Cytoband: 19p13.11 | ||
| Entrez ID: 79086 | HGNC ID: HGNC:28419 | Ensembl Gene: ENSG00000214046 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SMIM7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SMIM7 | 79086 | 224717_s_at | -0.3424 | 0.2599 | |
| GSE20347 | SMIM7 | 79086 | 219097_x_at | -0.0808 | 0.3590 | |
| GSE23400 | SMIM7 | 79086 | 219097_x_at | 0.0265 | 0.6597 | |
| GSE26886 | SMIM7 | 79086 | 224717_s_at | -0.2868 | 0.2664 | |
| GSE29001 | SMIM7 | 79086 | 219097_x_at | 0.0901 | 0.7151 | |
| GSE38129 | SMIM7 | 79086 | 219097_x_at | -0.0312 | 0.7198 | |
| GSE45670 | SMIM7 | 79086 | 224717_s_at | -0.0596 | 0.6992 | |
| GSE53622 | SMIM7 | 79086 | 119545 | -0.0747 | 0.2353 | |
| GSE53624 | SMIM7 | 79086 | 119545 | -0.0528 | 0.6635 | |
| GSE63941 | SMIM7 | 79086 | 219097_x_at | -0.2416 | 0.4330 | |
| GSE77861 | SMIM7 | 79086 | 224717_s_at | -0.0147 | 0.9556 | |
| SRP007169 | SMIM7 | 79086 | RNAseq | -0.3882 | 0.2991 | |
| SRP008496 | SMIM7 | 79086 | RNAseq | -0.2253 | 0.2697 | |
| SRP064894 | SMIM7 | 79086 | RNAseq | 0.2456 | 0.3383 | |
| SRP133303 | SMIM7 | 79086 | RNAseq | -0.2267 | 0.0862 | |
| SRP159526 | SMIM7 | 79086 | RNAseq | 0.0206 | 0.9298 | |
| SRP193095 | SMIM7 | 79086 | RNAseq | -0.2813 | 0.0013 | |
| SRP219564 | SMIM7 | 79086 | RNAseq | 0.1588 | 0.4386 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SMIM7 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of SMIM7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SMIM7 | 79086 | 4 | 3 | 23 | |
| GSE20123 | SMIM7 | 79086 | 3 | 2 | 25 | |
| GSE43470 | SMIM7 | 79086 | 2 | 6 | 35 | |
| GSE46452 | SMIM7 | 79086 | 47 | 1 | 11 | |
| GSE47630 | SMIM7 | 79086 | 4 | 8 | 28 | |
| GSE54993 | SMIM7 | 79086 | 15 | 4 | 51 | |
| GSE54994 | SMIM7 | 79086 | 6 | 14 | 33 | |
| GSE60625 | SMIM7 | 79086 | 9 | 0 | 2 | |
| GSE74703 | SMIM7 | 79086 | 2 | 4 | 30 | |
| GSE74704 | SMIM7 | 79086 | 0 | 1 | 19 | |
| TCGA | SMIM7 | 79086 | 17 | 9 | 70 |
Total number of gains: 109; Total number of losses: 52; Total Number of normals: 327.
Somatic mutations of SMIM7:
Generating mutation plots.
Highly correlated genes for SMIM7:
Showing top 20/53 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SMIM7 | IDH1 | 0.652787 | 4 | 0 | 4 |
| SMIM7 | VPS29 | 0.652532 | 3 | 0 | 3 |
| SMIM7 | CSNK1G3 | 0.629333 | 3 | 0 | 3 |
| SMIM7 | PSMD10 | 0.626872 | 4 | 0 | 4 |
| SMIM7 | TMEM62 | 0.611888 | 3 | 0 | 3 |
| SMIM7 | FASTKD2 | 0.601011 | 4 | 0 | 3 |
| SMIM7 | CCNDBP1 | 0.59711 | 4 | 0 | 3 |
| SMIM7 | GABPA | 0.593816 | 3 | 0 | 3 |
| SMIM7 | PPP1R2 | 0.593613 | 3 | 0 | 3 |
| SMIM7 | MICU2 | 0.593298 | 3 | 0 | 3 |
| SMIM7 | TMEM218 | 0.592519 | 5 | 0 | 3 |
| SMIM7 | RASSF9 | 0.588169 | 4 | 0 | 3 |
| SMIM7 | VAMP7 | 0.587797 | 3 | 0 | 3 |
| SMIM7 | TRIM4 | 0.585647 | 3 | 0 | 3 |
| SMIM7 | CD9 | 0.585601 | 4 | 0 | 3 |
| SMIM7 | UNC50 | 0.578135 | 4 | 0 | 3 |
| SMIM7 | DHRS7B | 0.577793 | 5 | 0 | 3 |
| SMIM7 | LRRC1 | 0.575282 | 5 | 0 | 3 |
| SMIM7 | CCSER2 | 0.565579 | 3 | 0 | 3 |
| SMIM7 | MFAP1 | 0.563461 | 4 | 0 | 4 |
For details and further investigation, click here
