| Full name: tripartite motif containing 4 | Alias Symbol: RNF87 | ||
| Type: protein-coding gene | Cytoband: 7q22.1 | ||
| Entrez ID: 89122 | HGNC ID: HGNC:16275 | Ensembl Gene: ENSG00000146833 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TRIM4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRIM4 | 89122 | 223384_s_at | -0.2797 | 0.6246 | |
| GSE26886 | TRIM4 | 89122 | 223384_s_at | -0.1984 | 0.4985 | |
| GSE45670 | TRIM4 | 89122 | 223384_s_at | -0.2401 | 0.2489 | |
| GSE53622 | TRIM4 | 89122 | 76440 | -0.8267 | 0.0000 | |
| GSE53624 | TRIM4 | 89122 | 76440 | -0.6496 | 0.0000 | |
| GSE63941 | TRIM4 | 89122 | 223384_s_at | -0.7223 | 0.2636 | |
| GSE77861 | TRIM4 | 89122 | 224159_x_at | -0.0602 | 0.7532 | |
| GSE97050 | TRIM4 | 89122 | A_23_P500601 | -0.4694 | 0.2261 | |
| SRP007169 | TRIM4 | 89122 | RNAseq | 0.4105 | 0.3229 | |
| SRP008496 | TRIM4 | 89122 | RNAseq | 0.9683 | 0.0076 | |
| SRP064894 | TRIM4 | 89122 | RNAseq | -0.1229 | 0.3913 | |
| SRP133303 | TRIM4 | 89122 | RNAseq | -0.0144 | 0.8727 | |
| SRP159526 | TRIM4 | 89122 | RNAseq | -0.2941 | 0.1774 | |
| SRP193095 | TRIM4 | 89122 | RNAseq | 0.0834 | 0.4726 | |
| SRP219564 | TRIM4 | 89122 | RNAseq | 0.3605 | 0.3037 | |
| TCGA | TRIM4 | 89122 | RNAseq | -0.1235 | 0.0278 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TRIM4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRIM4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRIM4 | 89122 | 13 | 0 | 17 | |
| GSE20123 | TRIM4 | 89122 | 13 | 0 | 17 | |
| GSE43470 | TRIM4 | 89122 | 6 | 2 | 35 | |
| GSE46452 | TRIM4 | 89122 | 11 | 1 | 47 | |
| GSE47630 | TRIM4 | 89122 | 7 | 3 | 30 | |
| GSE54993 | TRIM4 | 89122 | 1 | 9 | 60 | |
| GSE54994 | TRIM4 | 89122 | 16 | 3 | 34 | |
| GSE60625 | TRIM4 | 89122 | 0 | 0 | 11 | |
| GSE74703 | TRIM4 | 89122 | 6 | 1 | 29 | |
| GSE74704 | TRIM4 | 89122 | 9 | 0 | 11 | |
| TCGA | TRIM4 | 89122 | 52 | 6 | 38 |
Total number of gains: 134; Total number of losses: 25; Total Number of normals: 329.
Somatic mutations of TRIM4:
Generating mutation plots.
Highly correlated genes for TRIM4:
Showing top 20/104 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRIM4 | AGFG2 | 0.657255 | 4 | 0 | 3 |
| TRIM4 | SOX5 | 0.651321 | 4 | 0 | 3 |
| TRIM4 | TMEM219 | 0.636659 | 3 | 0 | 3 |
| TRIM4 | SERPINB6 | 0.629805 | 5 | 0 | 3 |
| TRIM4 | COG7 | 0.620771 | 3 | 0 | 3 |
| TRIM4 | ABLIM1 | 0.612987 | 4 | 0 | 3 |
| TRIM4 | TCP11L2 | 0.608541 | 4 | 0 | 3 |
| TRIM4 | CHP1 | 0.607359 | 3 | 0 | 3 |
| TRIM4 | ATE1 | 0.607151 | 4 | 0 | 3 |
| TRIM4 | LMBRD2 | 0.605768 | 3 | 0 | 3 |
| TRIM4 | NUCB2 | 0.601574 | 4 | 0 | 3 |
| TRIM4 | FMO2 | 0.59759 | 4 | 0 | 4 |
| TRIM4 | CYP2C18 | 0.594917 | 3 | 0 | 3 |
| TRIM4 | LGI1 | 0.591535 | 4 | 0 | 3 |
| TRIM4 | PARP16 | 0.585966 | 4 | 0 | 3 |
| TRIM4 | SMIM7 | 0.585647 | 3 | 0 | 3 |
| TRIM4 | ANXA11 | 0.582257 | 5 | 0 | 3 |
| TRIM4 | HIGD1A | 0.58111 | 3 | 0 | 3 |
| TRIM4 | ATP8B1 | 0.57583 | 5 | 0 | 4 |
| TRIM4 | ACKR1 | 0.571955 | 3 | 0 | 3 |
For details and further investigation, click here
