| Full name: dehydrogenase/reductase 7B | Alias Symbol: DKFZp566O084|MGC8916|CGI-93|SDR32C1 | ||
| Type: protein-coding gene | Cytoband: 17p11.2 | ||
| Entrez ID: 25979 | HGNC ID: HGNC:24547 | Ensembl Gene: ENSG00000109016 | OMIM ID: 616160 |
| Drug and gene relationship at DGIdb | |||
Expression of DHRS7B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DHRS7B | 25979 | 220690_s_at | -0.1409 | 0.8013 | |
| GSE20347 | DHRS7B | 25979 | 220690_s_at | -0.2695 | 0.1232 | |
| GSE23400 | DHRS7B | 25979 | 220690_s_at | 0.1732 | 0.0170 | |
| GSE26886 | DHRS7B | 25979 | 220690_s_at | -0.1533 | 0.5843 | |
| GSE29001 | DHRS7B | 25979 | 220690_s_at | -0.1640 | 0.4935 | |
| GSE38129 | DHRS7B | 25979 | 220690_s_at | -0.0235 | 0.9225 | |
| GSE45670 | DHRS7B | 25979 | 220690_s_at | 0.0276 | 0.8816 | |
| GSE53622 | DHRS7B | 25979 | 131694 | -0.1917 | 0.0013 | |
| GSE53624 | DHRS7B | 25979 | 131694 | -0.1743 | 0.0065 | |
| GSE63941 | DHRS7B | 25979 | 220690_s_at | 0.2631 | 0.6235 | |
| GSE77861 | DHRS7B | 25979 | 220690_s_at | -0.0120 | 0.9744 | |
| GSE97050 | DHRS7B | 25979 | A_23_P141208 | 0.1957 | 0.3739 | |
| SRP007169 | DHRS7B | 25979 | RNAseq | -0.4089 | 0.3806 | |
| SRP008496 | DHRS7B | 25979 | RNAseq | -0.4470 | 0.1149 | |
| SRP064894 | DHRS7B | 25979 | RNAseq | 0.5511 | 0.0620 | |
| SRP133303 | DHRS7B | 25979 | RNAseq | -0.0385 | 0.7775 | |
| SRP159526 | DHRS7B | 25979 | RNAseq | -0.1439 | 0.4901 | |
| SRP193095 | DHRS7B | 25979 | RNAseq | -0.3715 | 0.0056 | |
| SRP219564 | DHRS7B | 25979 | RNAseq | 0.3208 | 0.3366 | |
| TCGA | DHRS7B | 25979 | RNAseq | -0.1965 | 0.0044 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DHRS7B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DHRS7B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DHRS7B | 25979 | 4 | 5 | 21 | |
| GSE20123 | DHRS7B | 25979 | 4 | 6 | 20 | |
| GSE43470 | DHRS7B | 25979 | 1 | 5 | 37 | |
| GSE46452 | DHRS7B | 25979 | 34 | 1 | 24 | |
| GSE47630 | DHRS7B | 25979 | 7 | 1 | 32 | |
| GSE54993 | DHRS7B | 25979 | 2 | 4 | 64 | |
| GSE54994 | DHRS7B | 25979 | 6 | 6 | 41 | |
| GSE60625 | DHRS7B | 25979 | 4 | 0 | 7 | |
| GSE74703 | DHRS7B | 25979 | 1 | 2 | 33 | |
| GSE74704 | DHRS7B | 25979 | 2 | 2 | 16 | |
| TCGA | DHRS7B | 25979 | 18 | 24 | 54 |
Total number of gains: 83; Total number of losses: 56; Total Number of normals: 349.
Somatic mutations of DHRS7B:
Generating mutation plots.
Highly correlated genes for DHRS7B:
Showing top 20/39 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DHRS7B | C15orf40 | 0.759998 | 3 | 0 | 3 |
| DHRS7B | TMEM125 | 0.737793 | 3 | 0 | 3 |
| DHRS7B | STK16 | 0.685898 | 3 | 0 | 3 |
| DHRS7B | MRS2 | 0.643558 | 3 | 0 | 3 |
| DHRS7B | DRG2 | 0.642348 | 4 | 0 | 4 |
| DHRS7B | HOGA1 | 0.637572 | 3 | 0 | 3 |
| DHRS7B | PNPLA4 | 0.634531 | 3 | 0 | 3 |
| DHRS7B | LAMTOR2 | 0.617185 | 4 | 0 | 3 |
| DHRS7B | CORO2A | 0.606358 | 4 | 0 | 3 |
| DHRS7B | CNIH1 | 0.600602 | 3 | 0 | 3 |
| DHRS7B | SMIM7 | 0.577793 | 5 | 0 | 3 |
| DHRS7B | POC1B | 0.575319 | 4 | 0 | 3 |
| DHRS7B | CRY1 | 0.57366 | 3 | 0 | 3 |
| DHRS7B | RPL6 | 0.558326 | 3 | 0 | 3 |
| DHRS7B | MED11 | 0.555303 | 4 | 0 | 3 |
| DHRS7B | CLN3 | 0.553457 | 6 | 0 | 3 |
| DHRS7B | TMEM87A | 0.550881 | 5 | 0 | 3 |
| DHRS7B | MRPL23 | 0.548553 | 6 | 0 | 4 |
| DHRS7B | ZNF624 | 0.546924 | 7 | 0 | 4 |
| DHRS7B | RPS18 | 0.544248 | 3 | 0 | 3 |
For details and further investigation, click here
