| Full name: leucine rich repeat containing 1 | Alias Symbol: dJ523E19.1|LANO|FLJ10775|FLJ11834 | ||
| Type: protein-coding gene | Cytoband: 6p12.1 | ||
| Entrez ID: 55227 | HGNC ID: HGNC:14307 | Ensembl Gene: ENSG00000137269 | OMIM ID: 608195 |
| Drug and gene relationship at DGIdb | |||
Expression of LRRC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRC1 | 55227 | 218816_at | -0.1647 | 0.8436 | |
| GSE20347 | LRRC1 | 55227 | 218816_at | -0.2431 | 0.1927 | |
| GSE23400 | LRRC1 | 55227 | 218816_at | 0.1505 | 0.1742 | |
| GSE26886 | LRRC1 | 55227 | 218816_at | -0.2693 | 0.1280 | |
| GSE29001 | LRRC1 | 55227 | 218816_at | 0.1207 | 0.6292 | |
| GSE38129 | LRRC1 | 55227 | 218816_at | 0.0796 | 0.7052 | |
| GSE45670 | LRRC1 | 55227 | 218816_at | 0.2223 | 0.2461 | |
| GSE53622 | LRRC1 | 55227 | 4313 | -0.0413 | 0.7435 | |
| GSE53624 | LRRC1 | 55227 | 4313 | -0.0571 | 0.5406 | |
| GSE63941 | LRRC1 | 55227 | 218816_at | 1.6349 | 0.0018 | |
| GSE77861 | LRRC1 | 55227 | 218816_at | 0.3085 | 0.4057 | |
| GSE97050 | LRRC1 | 55227 | A_33_P3293386 | -0.1086 | 0.6450 | |
| SRP007169 | LRRC1 | 55227 | RNAseq | -0.2357 | 0.5694 | |
| SRP008496 | LRRC1 | 55227 | RNAseq | -0.2811 | 0.3235 | |
| SRP064894 | LRRC1 | 55227 | RNAseq | -0.5449 | 0.0090 | |
| SRP133303 | LRRC1 | 55227 | RNAseq | -0.0700 | 0.6611 | |
| SRP159526 | LRRC1 | 55227 | RNAseq | 0.0505 | 0.8564 | |
| SRP193095 | LRRC1 | 55227 | RNAseq | -0.3252 | 0.0146 | |
| SRP219564 | LRRC1 | 55227 | RNAseq | -0.0943 | 0.8460 | |
| TCGA | LRRC1 | 55227 | RNAseq | 0.0737 | 0.2647 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by LRRC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRRC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRC1 | 55227 | 7 | 2 | 21 | |
| GSE20123 | LRRC1 | 55227 | 7 | 2 | 21 | |
| GSE43470 | LRRC1 | 55227 | 5 | 0 | 38 | |
| GSE46452 | LRRC1 | 55227 | 2 | 10 | 47 | |
| GSE47630 | LRRC1 | 55227 | 7 | 5 | 28 | |
| GSE54993 | LRRC1 | 55227 | 3 | 1 | 66 | |
| GSE54994 | LRRC1 | 55227 | 9 | 4 | 40 | |
| GSE60625 | LRRC1 | 55227 | 0 | 3 | 8 | |
| GSE74703 | LRRC1 | 55227 | 5 | 0 | 31 | |
| GSE74704 | LRRC1 | 55227 | 2 | 1 | 17 | |
| TCGA | LRRC1 | 55227 | 22 | 13 | 61 |
Total number of gains: 69; Total number of losses: 41; Total Number of normals: 378.
Somatic mutations of LRRC1:
Generating mutation plots.
Highly correlated genes for LRRC1:
Showing top 20/162 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRC1 | IMPACT | 0.677901 | 4 | 0 | 3 |
| LRRC1 | ZNHIT3 | 0.647456 | 3 | 0 | 3 |
| LRRC1 | SUPT4H1 | 0.645837 | 4 | 0 | 4 |
| LRRC1 | PPP1CC | 0.629228 | 4 | 0 | 3 |
| LRRC1 | GLTP | 0.623932 | 4 | 0 | 3 |
| LRRC1 | VAMP8 | 0.622918 | 5 | 0 | 4 |
| LRRC1 | SIRT7 | 0.616598 | 3 | 0 | 3 |
| LRRC1 | DHCR24 | 0.615159 | 4 | 0 | 3 |
| LRRC1 | ERI2 | 0.611972 | 6 | 0 | 4 |
| LRRC1 | STOML2 | 0.609251 | 3 | 0 | 3 |
| LRRC1 | PLS1 | 0.608037 | 5 | 0 | 3 |
| LRRC1 | METAP2 | 0.607424 | 3 | 0 | 3 |
| LRRC1 | TTC22 | 0.606433 | 5 | 0 | 4 |
| LRRC1 | LMTK2 | 0.59766 | 4 | 0 | 3 |
| LRRC1 | RLF | 0.597581 | 3 | 0 | 3 |
| LRRC1 | MRPS7 | 0.59546 | 4 | 0 | 4 |
| LRRC1 | ARPC3 | 0.595107 | 6 | 0 | 4 |
| LRRC1 | JUP | 0.594979 | 7 | 0 | 4 |
| LRRC1 | COIL | 0.59258 | 5 | 0 | 3 |
| LRRC1 | GALK2 | 0.592078 | 4 | 0 | 4 |
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