MICU2

 

Full name: mitochondrial calcium uptake 2 Alias Symbol: 
Type: protein-coding gene Cytoband: 13q12.11
Entrez ID: 221154 HGNC ID: HGNC:31830 Ensembl Gene: ENSG00000165487 OMIM ID: 610632

 

Expression of MICU2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MICU2 221154 212410_at -0.4145 0.2474
GSE20347 MICU2 221154 212410_at -0.4888 0.0011
GSE23400 MICU2 221154 212410_at -0.1772 0.0888
GSE26886 MICU2 221154 212410_at -0.1555 0.6418
GSE29001 MICU2 221154 212410_at -0.5163 0.2364
GSE38129 MICU2 221154 212410_at -0.3740 0.0101
GSE45670 MICU2 221154 212410_at -0.2638 0.2324
GSE53622 MICU2 221154 29814 -0.2883 0.0000
GSE53624 MICU2 221154 29814 -0.3267 0.0000
GSE63941 MICU2 221154 212410_at -0.7066 0.2269
GSE77861 MICU2 221154 212410_at -0.3963 0.1438
SRP007169 MICU2 221154 RNAseq -1.3710 0.0002
SRP008496 MICU2 221154 RNAseq -1.1514 0.0000
SRP064894 MICU2 221154 RNAseq -0.3128 0.1373
SRP133303 MICU2 221154 RNAseq -0.1848 0.2529
SRP159526 MICU2 221154 RNAseq -0.6774 0.0221
SRP193095 MICU2 221154 RNAseq -0.6749 0.0000
SRP219564 MICU2 221154 RNAseq -0.5883 0.0534

Upregulated datasets: 0; Downregulated datasets: 2.  


 

Survival by MICU2 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  


Copy number change of MICU2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MICU2 221154 1 14 15
GSE20123 MICU2 221154 1 13 16
GSE43470 MICU2 221154 2 13 28
GSE46452 MICU2 221154 0 33 26
GSE47630 MICU2 221154 3 26 11
GSE54993 MICU2 221154 11 2 57
GSE54994 MICU2 221154 1 13 39
GSE60625 MICU2 221154 0 3 8
GSE74703 MICU2 221154 2 10 24
GSE74704 MICU2 221154 0 11 9
TCGA MICU2 221154 6 42 48

Total number of gains: 27; Total number of losses: 180; Total Number of normals: 281.  


 

Somatic mutations of MICU2:

 

Generating mutation plots.

 

Highly correlated genes for MICU2:

 

Showing top 20/359 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MICU2SGMS10.70754303
MICU2MSH30.70134303
MICU2MED40.68413808
MICU2RB10.680047303
MICU2SAMD90.663201404
MICU2ATG4A0.662036403
MICU2ZNF830.661502303
MICU2SUGT10.655334303
MICU2TMEM87A0.642706404
MICU2RAB9A0.642142403
MICU2PTBP30.637759303
MICU2VPS360.636515605
MICU2COG60.632564705
MICU2CYB5R40.631861303
MICU2STAM20.627807706
MICU2COG50.627764403
MICU2COMMD10.626934303
MICU2RPS6KB10.624064403
MICU2INO80C0.623514303
MICU2SAP180.61983907

For details and further investigation, click here