| Full name: small nuclear RNA activating complex polypeptide 2 | Alias Symbol: SNAP45|PTFdelta | ||
| Type: protein-coding gene | Cytoband: 19p13 | ||
| Entrez ID: 6618 | HGNC ID: HGNC:11135 | Ensembl Gene: ENSG00000104976 | OMIM ID: 605076 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SNAPC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNAPC2 | 6618 | 204104_at | 0.2193 | 0.3753 | |
| GSE20347 | SNAPC2 | 6618 | 204104_at | 0.1385 | 0.1741 | |
| GSE23400 | SNAPC2 | 6618 | 204104_at | 0.0424 | 0.3994 | |
| GSE26886 | SNAPC2 | 6618 | 204104_at | 0.6898 | 0.0000 | |
| GSE29001 | SNAPC2 | 6618 | 204104_at | -0.1206 | 0.5336 | |
| GSE38129 | SNAPC2 | 6618 | 204104_at | -0.0342 | 0.7642 | |
| GSE45670 | SNAPC2 | 6618 | 204104_at | -0.1370 | 0.2037 | |
| GSE63941 | SNAPC2 | 6618 | 204104_at | 1.0412 | 0.0007 | |
| GSE77861 | SNAPC2 | 6618 | 204104_at | 0.2856 | 0.2481 | |
| GSE97050 | SNAPC2 | 6618 | A_33_P3375383 | 0.0910 | 0.7060 | |
| SRP007169 | SNAPC2 | 6618 | RNAseq | 0.4024 | 0.4497 | |
| SRP008496 | SNAPC2 | 6618 | RNAseq | 0.5625 | 0.0923 | |
| SRP064894 | SNAPC2 | 6618 | RNAseq | 0.8197 | 0.0140 | |
| SRP133303 | SNAPC2 | 6618 | RNAseq | 0.2422 | 0.2714 | |
| SRP159526 | SNAPC2 | 6618 | RNAseq | 0.5583 | 0.0717 | |
| SRP193095 | SNAPC2 | 6618 | RNAseq | 0.3783 | 0.0090 | |
| SRP219564 | SNAPC2 | 6618 | RNAseq | 0.6521 | 0.2416 | |
| TCGA | SNAPC2 | 6618 | RNAseq | 0.1156 | 0.0883 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SNAPC2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of SNAPC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNAPC2 | 6618 | 4 | 3 | 23 | |
| GSE20123 | SNAPC2 | 6618 | 3 | 2 | 25 | |
| GSE43470 | SNAPC2 | 6618 | 2 | 7 | 34 | |
| GSE46452 | SNAPC2 | 6618 | 47 | 1 | 11 | |
| GSE47630 | SNAPC2 | 6618 | 5 | 7 | 28 | |
| GSE54993 | SNAPC2 | 6618 | 16 | 3 | 51 | |
| GSE54994 | SNAPC2 | 6618 | 6 | 14 | 33 | |
| GSE60625 | SNAPC2 | 6618 | 9 | 0 | 2 | |
| GSE74703 | SNAPC2 | 6618 | 2 | 4 | 30 | |
| GSE74704 | SNAPC2 | 6618 | 0 | 2 | 18 | |
| TCGA | SNAPC2 | 6618 | 9 | 20 | 67 |
Total number of gains: 103; Total number of losses: 63; Total Number of normals: 322.
Somatic mutations of SNAPC2:
Generating mutation plots.
Highly correlated genes for SNAPC2:
Showing top 20/781 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNAPC2 | LRCH3 | 0.800827 | 3 | 0 | 3 |
| SNAPC2 | KPNA1 | 0.793864 | 3 | 0 | 3 |
| SNAPC2 | TTF1 | 0.789465 | 3 | 0 | 3 |
| SNAPC2 | SLC43A2 | 0.783267 | 3 | 0 | 3 |
| SNAPC2 | MRPL55 | 0.776833 | 4 | 0 | 4 |
| SNAPC2 | MRPL36 | 0.772478 | 3 | 0 | 3 |
| SNAPC2 | MMP15 | 0.769177 | 4 | 0 | 4 |
| SNAPC2 | CPT1C | 0.762501 | 3 | 0 | 3 |
| SNAPC2 | SLC41A1 | 0.759127 | 3 | 0 | 3 |
| SNAPC2 | LMF2 | 0.757824 | 3 | 0 | 3 |
| SNAPC2 | TP53I13 | 0.757417 | 4 | 0 | 4 |
| SNAPC2 | GAS2L1 | 0.756986 | 3 | 0 | 3 |
| SNAPC2 | ELOF1 | 0.755724 | 3 | 0 | 3 |
| SNAPC2 | DVL3 | 0.754104 | 3 | 0 | 3 |
| SNAPC2 | TSPYL2 | 0.753071 | 4 | 0 | 4 |
| SNAPC2 | RPTOR | 0.752749 | 4 | 0 | 4 |
| SNAPC2 | XYLT2 | 0.75227 | 4 | 0 | 3 |
| SNAPC2 | GMEB2 | 0.751996 | 3 | 0 | 3 |
| SNAPC2 | DNTTIP1 | 0.750079 | 3 | 0 | 3 |
| SNAPC2 | SLC39A14 | 0.750078 | 3 | 0 | 3 |
For details and further investigation, click here
