| Full name: deoxynucleotidyltransferase terminal interacting protein 1 | Alias Symbol: dJ447F3.4|Tdif1 | ||
| Type: protein-coding gene | Cytoband: 20q13.12 | ||
| Entrez ID: 116092 | HGNC ID: HGNC:16160 | Ensembl Gene: ENSG00000101457 | OMIM ID: 611388 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of DNTTIP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNTTIP1 | 116092 | 224825_at | 0.5311 | 0.2840 | |
| GSE26886 | DNTTIP1 | 116092 | 224825_at | 0.7185 | 0.0000 | |
| GSE45670 | DNTTIP1 | 116092 | 224825_at | 0.2620 | 0.1086 | |
| GSE53622 | DNTTIP1 | 116092 | 75736 | 0.6719 | 0.0000 | |
| GSE53624 | DNTTIP1 | 116092 | 75736 | 0.7255 | 0.0000 | |
| GSE63941 | DNTTIP1 | 116092 | 224825_at | 0.7458 | 0.1305 | |
| GSE77861 | DNTTIP1 | 116092 | 224825_at | 0.3132 | 0.1219 | |
| GSE97050 | DNTTIP1 | 116092 | A_23_P131816 | 0.8393 | 0.1334 | |
| SRP007169 | DNTTIP1 | 116092 | RNAseq | 0.1042 | 0.7774 | |
| SRP008496 | DNTTIP1 | 116092 | RNAseq | 0.3013 | 0.2990 | |
| SRP064894 | DNTTIP1 | 116092 | RNAseq | 0.6689 | 0.0006 | |
| SRP133303 | DNTTIP1 | 116092 | RNAseq | 0.8213 | 0.0000 | |
| SRP159526 | DNTTIP1 | 116092 | RNAseq | 0.6933 | 0.0008 | |
| SRP193095 | DNTTIP1 | 116092 | RNAseq | 0.4678 | 0.0004 | |
| SRP219564 | DNTTIP1 | 116092 | RNAseq | 0.5045 | 0.0912 | |
| TCGA | DNTTIP1 | 116092 | RNAseq | 0.1569 | 0.0062 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DNTTIP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNTTIP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNTTIP1 | 116092 | 14 | 1 | 15 | |
| GSE20123 | DNTTIP1 | 116092 | 14 | 1 | 15 | |
| GSE43470 | DNTTIP1 | 116092 | 12 | 1 | 30 | |
| GSE46452 | DNTTIP1 | 116092 | 29 | 0 | 30 | |
| GSE47630 | DNTTIP1 | 116092 | 24 | 1 | 15 | |
| GSE54993 | DNTTIP1 | 116092 | 0 | 18 | 52 | |
| GSE54994 | DNTTIP1 | 116092 | 25 | 0 | 28 | |
| GSE60625 | DNTTIP1 | 116092 | 0 | 0 | 11 | |
| GSE74703 | DNTTIP1 | 116092 | 10 | 1 | 25 | |
| GSE74704 | DNTTIP1 | 116092 | 10 | 0 | 10 | |
| TCGA | DNTTIP1 | 116092 | 46 | 3 | 47 |
Total number of gains: 184; Total number of losses: 26; Total Number of normals: 278.
Somatic mutations of DNTTIP1:
Generating mutation plots.
Highly correlated genes for DNTTIP1:
Showing top 20/1709 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNTTIP1 | GNS | 0.815473 | 3 | 0 | 3 |
| DNTTIP1 | NPRL3 | 0.801716 | 4 | 0 | 4 |
| DNTTIP1 | C19orf54 | 0.784997 | 4 | 0 | 4 |
| DNTTIP1 | GTF3C2 | 0.777739 | 3 | 0 | 3 |
| DNTTIP1 | WIZ | 0.775126 | 3 | 0 | 3 |
| DNTTIP1 | AP3D1 | 0.763426 | 3 | 0 | 3 |
| DNTTIP1 | RCN2 | 0.757164 | 3 | 0 | 3 |
| DNTTIP1 | POLA1 | 0.751424 | 3 | 0 | 3 |
| DNTTIP1 | RPL26L1 | 0.751422 | 4 | 0 | 3 |
| DNTTIP1 | SNAPC2 | 0.750079 | 3 | 0 | 3 |
| DNTTIP1 | PDS5B | 0.749174 | 3 | 0 | 3 |
| DNTTIP1 | HNRNPUL1 | 0.749119 | 3 | 0 | 3 |
| DNTTIP1 | RRN3 | 0.747299 | 3 | 0 | 3 |
| DNTTIP1 | MGAT4B | 0.746891 | 3 | 0 | 3 |
| DNTTIP1 | ADCY3 | 0.745853 | 4 | 0 | 3 |
| DNTTIP1 | DHX40 | 0.745549 | 3 | 0 | 3 |
| DNTTIP1 | HEATR6 | 0.741375 | 5 | 0 | 5 |
| DNTTIP1 | BRD4 | 0.73793 | 3 | 0 | 3 |
| DNTTIP1 | AUP1 | 0.737782 | 4 | 0 | 4 |
| DNTTIP1 | DHODH | 0.735994 | 4 | 0 | 4 |
For details and further investigation, click here
