| Full name: component of oligomeric golgi complex 6 | Alias Symbol: COD2|KIAA1134 | ||
| Type: protein-coding gene | Cytoband: 13q14.11 | ||
| Entrez ID: 57511 | HGNC ID: HGNC:18621 | Ensembl Gene: ENSG00000133103 | OMIM ID: 606977 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of COG6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COG6 | 57511 | 225769_at | -0.2093 | 0.5841 | |
| GSE26886 | COG6 | 57511 | 225769_at | -1.3390 | 0.0019 | |
| GSE45670 | COG6 | 57511 | 225769_at | -0.2947 | 0.0720 | |
| GSE53622 | COG6 | 57511 | 12746 | -0.1547 | 0.0239 | |
| GSE53624 | COG6 | 57511 | 14339 | -0.2694 | 0.0002 | |
| GSE63941 | COG6 | 57511 | 225769_at | -1.0185 | 0.0168 | |
| GSE77861 | COG6 | 57511 | 225769_at | -0.5485 | 0.0453 | |
| GSE97050 | COG6 | 57511 | A_23_P53866 | -0.0590 | 0.8233 | |
| SRP007169 | COG6 | 57511 | RNAseq | -0.7564 | 0.0252 | |
| SRP008496 | COG6 | 57511 | RNAseq | -0.3862 | 0.0421 | |
| SRP064894 | COG6 | 57511 | RNAseq | 0.0270 | 0.9205 | |
| SRP133303 | COG6 | 57511 | RNAseq | -0.0656 | 0.7130 | |
| SRP159526 | COG6 | 57511 | RNAseq | -0.8255 | 0.0002 | |
| SRP193095 | COG6 | 57511 | RNAseq | -0.5861 | 0.0000 | |
| SRP219564 | COG6 | 57511 | RNAseq | -0.3030 | 0.4174 | |
| TCGA | COG6 | 57511 | RNAseq | -0.1362 | 0.0132 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by COG6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COG6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COG6 | 57511 | 0 | 16 | 14 | |
| GSE20123 | COG6 | 57511 | 0 | 15 | 15 | |
| GSE43470 | COG6 | 57511 | 3 | 13 | 27 | |
| GSE46452 | COG6 | 57511 | 0 | 33 | 26 | |
| GSE47630 | COG6 | 57511 | 2 | 27 | 11 | |
| GSE54993 | COG6 | 57511 | 12 | 2 | 56 | |
| GSE54994 | COG6 | 57511 | 1 | 17 | 35 | |
| GSE60625 | COG6 | 57511 | 0 | 3 | 8 | |
| GSE74703 | COG6 | 57511 | 3 | 10 | 23 | |
| GSE74704 | COG6 | 57511 | 0 | 12 | 8 | |
| TCGA | COG6 | 57511 | 7 | 40 | 49 |
Total number of gains: 28; Total number of losses: 188; Total Number of normals: 272.
Somatic mutations of COG6:
Generating mutation plots.
Highly correlated genes for COG6:
Showing top 20/854 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COG6 | ARHGEF7 | 0.816767 | 3 | 0 | 3 |
| COG6 | ELMO2 | 0.79294 | 4 | 0 | 4 |
| COG6 | COPG2 | 0.786755 | 3 | 0 | 3 |
| COG6 | YTHDC2 | 0.782216 | 4 | 0 | 4 |
| COG6 | ZNF92 | 0.779626 | 3 | 0 | 3 |
| COG6 | TTC39B | 0.778821 | 3 | 0 | 3 |
| COG6 | NAA35 | 0.773948 | 3 | 0 | 3 |
| COG6 | COBLL1 | 0.772115 | 3 | 0 | 3 |
| COG6 | TMEM50B | 0.770434 | 3 | 0 | 3 |
| COG6 | IMPA1 | 0.770426 | 3 | 0 | 3 |
| COG6 | DECR1 | 0.768686 | 3 | 0 | 3 |
| COG6 | AGTPBP1 | 0.764512 | 3 | 0 | 3 |
| COG6 | KLHL3 | 0.763521 | 3 | 0 | 3 |
| COG6 | CETN3 | 0.756939 | 4 | 0 | 4 |
| COG6 | GOLGA5 | 0.756579 | 3 | 0 | 3 |
| COG6 | RRAGA | 0.755229 | 3 | 0 | 3 |
| COG6 | KIAA0355 | 0.747213 | 3 | 0 | 3 |
| COG6 | SON | 0.743145 | 3 | 0 | 3 |
| COG6 | RPUSD4 | 0.732459 | 3 | 0 | 3 |
| COG6 | GAPVD1 | 0.730391 | 3 | 0 | 3 |
For details and further investigation, click here
