| Full name: acyl-CoA synthetase short chain family member 3 | Alias Symbol: FLJ21963 | ||
| Type: protein-coding gene | Cytoband: 12q21.31 | ||
| Entrez ID: 79611 | HGNC ID: HGNC:24723 | Ensembl Gene: ENSG00000111058 | OMIM ID: 614356 |
| Drug and gene relationship at DGIdb | |||
Expression of ACSS3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACSS3 | 79611 | 219616_at | -0.1860 | 0.5751 | |
| GSE20347 | ACSS3 | 79611 | 219616_at | -0.1217 | 0.0795 | |
| GSE23400 | ACSS3 | 79611 | 219616_at | -0.1429 | 0.0003 | |
| GSE26886 | ACSS3 | 79611 | 219616_at | 0.1357 | 0.5631 | |
| GSE29001 | ACSS3 | 79611 | 219616_at | -0.0071 | 0.9769 | |
| GSE38129 | ACSS3 | 79611 | 219616_at | -0.2221 | 0.0448 | |
| GSE45670 | ACSS3 | 79611 | 219616_at | -0.2981 | 0.0527 | |
| GSE53622 | ACSS3 | 79611 | 18627 | -0.7999 | 0.0000 | |
| GSE53624 | ACSS3 | 79611 | 18627 | -0.4437 | 0.0127 | |
| GSE63941 | ACSS3 | 79611 | 219616_at | -1.9180 | 0.0024 | |
| GSE77861 | ACSS3 | 79611 | 219616_at | 0.0356 | 0.8618 | |
| GSE97050 | ACSS3 | 79611 | A_23_P339119 | 0.0279 | 0.9269 | |
| SRP007169 | ACSS3 | 79611 | RNAseq | -0.2298 | 0.7411 | |
| SRP064894 | ACSS3 | 79611 | RNAseq | -0.2000 | 0.6041 | |
| SRP133303 | ACSS3 | 79611 | RNAseq | -1.1514 | 0.0000 | |
| SRP159526 | ACSS3 | 79611 | RNAseq | 0.2437 | 0.6435 | |
| SRP193095 | ACSS3 | 79611 | RNAseq | 0.5300 | 0.0414 | |
| SRP219564 | ACSS3 | 79611 | RNAseq | -0.1575 | 0.7444 | |
| TCGA | ACSS3 | 79611 | RNAseq | -0.9236 | 0.0054 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by ACSS3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ACSS3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACSS3 | 79611 | 2 | 4 | 24 | |
| GSE20123 | ACSS3 | 79611 | 2 | 4 | 24 | |
| GSE43470 | ACSS3 | 79611 | 3 | 1 | 39 | |
| GSE46452 | ACSS3 | 79611 | 9 | 1 | 49 | |
| GSE47630 | ACSS3 | 79611 | 10 | 1 | 29 | |
| GSE54993 | ACSS3 | 79611 | 0 | 5 | 65 | |
| GSE54994 | ACSS3 | 79611 | 7 | 1 | 45 | |
| GSE60625 | ACSS3 | 79611 | 0 | 0 | 11 | |
| GSE74703 | ACSS3 | 79611 | 3 | 1 | 32 | |
| GSE74704 | ACSS3 | 79611 | 1 | 3 | 16 | |
| TCGA | ACSS3 | 79611 | 15 | 13 | 68 |
Total number of gains: 52; Total number of losses: 34; Total Number of normals: 402.
Somatic mutations of ACSS3:
Generating mutation plots.
Highly correlated genes for ACSS3:
Showing top 20/761 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACSS3 | CYP4V2 | 0.821307 | 3 | 0 | 3 |
| ACSS3 | RHOJ | 0.772852 | 4 | 0 | 4 |
| ACSS3 | FAM98B | 0.763665 | 3 | 0 | 3 |
| ACSS3 | C11orf96 | 0.757504 | 3 | 0 | 3 |
| ACSS3 | BMP6 | 0.749946 | 4 | 0 | 4 |
| ACSS3 | MACROD2 | 0.7416 | 4 | 0 | 4 |
| ACSS3 | TNFSF12 | 0.739791 | 3 | 0 | 3 |
| ACSS3 | ZNF626 | 0.739531 | 3 | 0 | 3 |
| ACSS3 | GNG2 | 0.737358 | 4 | 0 | 3 |
| ACSS3 | SCAF4 | 0.735999 | 3 | 0 | 3 |
| ACSS3 | SON | 0.735015 | 3 | 0 | 3 |
| ACSS3 | MRPS35 | 0.73475 | 3 | 0 | 3 |
| ACSS3 | GIMAP5 | 0.733295 | 3 | 0 | 3 |
| ACSS3 | SEC22C | 0.730303 | 3 | 0 | 3 |
| ACSS3 | DPP4 | 0.728552 | 3 | 0 | 3 |
| ACSS3 | VPS18 | 0.727689 | 3 | 0 | 3 |
| ACSS3 | ZNF703 | 0.714295 | 3 | 0 | 3 |
| ACSS3 | NEDD9 | 0.712189 | 3 | 0 | 3 |
| ACSS3 | CCNY | 0.710453 | 3 | 0 | 3 |
| ACSS3 | NFYB | 0.705959 | 3 | 0 | 3 |
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