| Full name: inositol hexakisphosphate kinase 1 | Alias Symbol: KIAA0263 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 9807 | HGNC ID: HGNC:18360 | Ensembl Gene: ENSG00000176095 | OMIM ID: 606991 |
| Drug and gene relationship at DGIdb | |||
Expression of IP6K1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IP6K1 | 9807 | 212439_at | 0.1976 | 0.5175 | |
| GSE20347 | IP6K1 | 9807 | 212439_at | -0.3421 | 0.0000 | |
| GSE23400 | IP6K1 | 9807 | 212439_at | -0.1557 | 0.0000 | |
| GSE26886 | IP6K1 | 9807 | 212439_at | -0.4257 | 0.0264 | |
| GSE29001 | IP6K1 | 9807 | 212439_at | -0.4229 | 0.0042 | |
| GSE38129 | IP6K1 | 9807 | 212439_at | -0.3415 | 0.0000 | |
| GSE45670 | IP6K1 | 9807 | 212439_at | -0.0226 | 0.7942 | |
| GSE53622 | IP6K1 | 9807 | 88801 | -0.1534 | 0.0045 | |
| GSE53624 | IP6K1 | 9807 | 88801 | -0.4096 | 0.0000 | |
| GSE63941 | IP6K1 | 9807 | 212439_at | -0.8874 | 0.0008 | |
| GSE77861 | IP6K1 | 9807 | 212439_at | -0.1083 | 0.3491 | |
| GSE97050 | IP6K1 | 9807 | A_33_P3320804 | -0.1588 | 0.4724 | |
| SRP007169 | IP6K1 | 9807 | RNAseq | -0.3073 | 0.5447 | |
| SRP008496 | IP6K1 | 9807 | RNAseq | -0.3354 | 0.3105 | |
| SRP064894 | IP6K1 | 9807 | RNAseq | -0.3751 | 0.0219 | |
| SRP133303 | IP6K1 | 9807 | RNAseq | -0.3862 | 0.0009 | |
| SRP159526 | IP6K1 | 9807 | RNAseq | -0.3644 | 0.0642 | |
| SRP193095 | IP6K1 | 9807 | RNAseq | -0.4578 | 0.0000 | |
| SRP219564 | IP6K1 | 9807 | RNAseq | -0.3011 | 0.2941 | |
| TCGA | IP6K1 | 9807 | RNAseq | -0.2046 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IP6K1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IP6K1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IP6K1 | 9807 | 0 | 18 | 12 | |
| GSE20123 | IP6K1 | 9807 | 0 | 19 | 11 | |
| GSE43470 | IP6K1 | 9807 | 0 | 18 | 25 | |
| GSE46452 | IP6K1 | 9807 | 2 | 16 | 41 | |
| GSE47630 | IP6K1 | 9807 | 1 | 24 | 15 | |
| GSE54993 | IP6K1 | 9807 | 6 | 2 | 62 | |
| GSE54994 | IP6K1 | 9807 | 0 | 36 | 17 | |
| GSE60625 | IP6K1 | 9807 | 5 | 0 | 6 | |
| GSE74703 | IP6K1 | 9807 | 0 | 14 | 22 | |
| GSE74704 | IP6K1 | 9807 | 0 | 12 | 8 | |
| TCGA | IP6K1 | 9807 | 0 | 77 | 19 |
Total number of gains: 14; Total number of losses: 236; Total Number of normals: 238.
Somatic mutations of IP6K1:
Generating mutation plots.
Highly correlated genes for IP6K1:
Showing top 20/536 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IP6K1 | ZNF578 | 0.823752 | 3 | 0 | 3 |
| IP6K1 | YPEL2 | 0.791034 | 3 | 0 | 3 |
| IP6K1 | ANKRD44 | 0.788685 | 3 | 0 | 3 |
| IP6K1 | ST6GALNAC6 | 0.782807 | 3 | 0 | 3 |
| IP6K1 | PACRGL | 0.758856 | 3 | 0 | 3 |
| IP6K1 | SON | 0.757 | 3 | 0 | 3 |
| IP6K1 | KLHL36 | 0.756335 | 3 | 0 | 3 |
| IP6K1 | ZNF610 | 0.743538 | 3 | 0 | 3 |
| IP6K1 | SCAF8 | 0.73704 | 3 | 0 | 3 |
| IP6K1 | VPS26B | 0.730431 | 5 | 0 | 5 |
| IP6K1 | SPSB4 | 0.729686 | 3 | 0 | 3 |
| IP6K1 | TOMM40L | 0.727272 | 3 | 0 | 3 |
| IP6K1 | CASKIN2 | 0.724826 | 4 | 0 | 3 |
| IP6K1 | SLC17A5 | 0.724569 | 3 | 0 | 3 |
| IP6K1 | TMEM53 | 0.72341 | 4 | 0 | 4 |
| IP6K1 | SLC39A3 | 0.723024 | 3 | 0 | 3 |
| IP6K1 | SFTPA2 | 0.722649 | 3 | 0 | 3 |
| IP6K1 | JAM3 | 0.720138 | 3 | 0 | 3 |
| IP6K1 | ADCK1 | 0.719984 | 3 | 0 | 3 |
| IP6K1 | NDUFS3 | 0.718979 | 3 | 0 | 3 |
For details and further investigation, click here
