| Full name: sperm associated antigen 9 | Alias Symbol: HSS|SYD1|KIAA0516|MGC14967|MGC74461|MGC117291|JLP|PHET|HLC4|FLJ13450|FLJ14006|FLJ26141|FLJ34602|CT89|JIP4|JIP-4|PIG6 | ||
| Type: protein-coding gene | Cytoband: 17q21.33 | ||
| Entrez ID: 9043 | HGNC ID: HGNC:14524 | Ensembl Gene: ENSG00000008294 | OMIM ID: 605430 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of SPAG9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPAG9 | 9043 | 212470_at | 0.0850 | 0.8772 | |
| GSE20347 | SPAG9 | 9043 | 212470_at | 0.2075 | 0.2702 | |
| GSE23400 | SPAG9 | 9043 | 212470_at | 0.3360 | 0.0001 | |
| GSE26886 | SPAG9 | 9043 | 212470_at | -0.0596 | 0.8021 | |
| GSE29001 | SPAG9 | 9043 | 212470_at | 0.0805 | 0.8502 | |
| GSE38129 | SPAG9 | 9043 | 212470_at | 0.2734 | 0.0213 | |
| GSE45670 | SPAG9 | 9043 | 212470_at | 0.0033 | 0.9893 | |
| GSE53622 | SPAG9 | 9043 | 26696 | 0.1041 | 0.1617 | |
| GSE53624 | SPAG9 | 9043 | 41060 | 0.1775 | 0.0032 | |
| GSE63941 | SPAG9 | 9043 | 212470_at | -0.4082 | 0.2589 | |
| GSE77861 | SPAG9 | 9043 | 212470_at | 0.8002 | 0.0029 | |
| GSE97050 | SPAG9 | 9043 | A_24_P8454 | 0.1182 | 0.6009 | |
| SRP007169 | SPAG9 | 9043 | RNAseq | 0.9978 | 0.0104 | |
| SRP008496 | SPAG9 | 9043 | RNAseq | 1.0982 | 0.0000 | |
| SRP064894 | SPAG9 | 9043 | RNAseq | -0.1124 | 0.6453 | |
| SRP133303 | SPAG9 | 9043 | RNAseq | 0.3894 | 0.0573 | |
| SRP159526 | SPAG9 | 9043 | RNAseq | -0.0273 | 0.8939 | |
| SRP193095 | SPAG9 | 9043 | RNAseq | 0.2767 | 0.0058 | |
| SRP219564 | SPAG9 | 9043 | RNAseq | -0.2600 | 0.4791 | |
| TCGA | SPAG9 | 9043 | RNAseq | -0.0034 | 0.9437 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SPAG9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SPAG9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPAG9 | 9043 | 5 | 2 | 23 | |
| GSE20123 | SPAG9 | 9043 | 5 | 2 | 23 | |
| GSE43470 | SPAG9 | 9043 | 3 | 2 | 38 | |
| GSE46452 | SPAG9 | 9043 | 32 | 0 | 27 | |
| GSE47630 | SPAG9 | 9043 | 9 | 0 | 31 | |
| GSE54993 | SPAG9 | 9043 | 2 | 4 | 64 | |
| GSE54994 | SPAG9 | 9043 | 8 | 6 | 39 | |
| GSE60625 | SPAG9 | 9043 | 4 | 0 | 7 | |
| GSE74703 | SPAG9 | 9043 | 3 | 2 | 31 | |
| GSE74704 | SPAG9 | 9043 | 4 | 1 | 15 | |
| TCGA | SPAG9 | 9043 | 26 | 8 | 62 |
Total number of gains: 101; Total number of losses: 27; Total Number of normals: 360.
Somatic mutations of SPAG9:
Generating mutation plots.
Highly correlated genes for SPAG9:
Showing top 20/511 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPAG9 | RBM22 | 0.765793 | 4 | 0 | 3 |
| SPAG9 | COMMD2 | 0.734701 | 3 | 0 | 3 |
| SPAG9 | RANBP6 | 0.733165 | 3 | 0 | 3 |
| SPAG9 | YIPF4 | 0.729646 | 4 | 0 | 4 |
| SPAG9 | RBM33 | 0.718362 | 3 | 0 | 3 |
| SPAG9 | C16orf72 | 0.716373 | 3 | 0 | 3 |
| SPAG9 | ITPA | 0.709157 | 3 | 0 | 3 |
| SPAG9 | MRPL45 | 0.70838 | 4 | 0 | 3 |
| SPAG9 | ZNF275 | 0.707311 | 3 | 0 | 3 |
| SPAG9 | IST1 | 0.707114 | 3 | 0 | 3 |
| SPAG9 | PDZD11 | 0.706346 | 3 | 0 | 3 |
| SPAG9 | TRADD | 0.703765 | 4 | 0 | 3 |
| SPAG9 | HAUS7 | 0.703624 | 3 | 0 | 3 |
| SPAG9 | IFI6 | 0.702372 | 3 | 0 | 3 |
| SPAG9 | RNF145 | 0.700878 | 4 | 0 | 4 |
| SPAG9 | MRPS5 | 0.700699 | 3 | 0 | 3 |
| SPAG9 | MITD1 | 0.699009 | 4 | 0 | 3 |
| SPAG9 | KCTD21 | 0.698611 | 3 | 0 | 3 |
| SPAG9 | EIF4G2 | 0.694698 | 4 | 0 | 4 |
| SPAG9 | EIF2S2 | 0.692324 | 10 | 0 | 8 |
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