| Full name: ring finger protein 145 | Alias Symbol: FLJ31951 | ||
| Type: protein-coding gene | Cytoband: 5q33.3 | ||
| Entrez ID: 153830 | HGNC ID: HGNC:20853 | Ensembl Gene: ENSG00000145860 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RNF145:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNF145 | 153830 | 226077_at | -0.0136 | 0.9911 | |
| GSE26886 | RNF145 | 153830 | 226077_at | -0.2260 | 0.4717 | |
| GSE45670 | RNF145 | 153830 | 226077_at | 0.2478 | 0.1512 | |
| GSE53622 | RNF145 | 153830 | 8262 | -0.2585 | 0.0040 | |
| GSE53624 | RNF145 | 153830 | 8262 | -0.2838 | 0.0002 | |
| GSE63941 | RNF145 | 153830 | 226077_at | -0.2332 | 0.6374 | |
| GSE77861 | RNF145 | 153830 | 226077_at | 0.5426 | 0.1215 | |
| GSE97050 | RNF145 | 153830 | A_24_P144773 | 0.3859 | 0.1378 | |
| SRP007169 | RNF145 | 153830 | RNAseq | -0.9895 | 0.0042 | |
| SRP008496 | RNF145 | 153830 | RNAseq | -0.9109 | 0.0000 | |
| SRP064894 | RNF145 | 153830 | RNAseq | 0.0090 | 0.9488 | |
| SRP133303 | RNF145 | 153830 | RNAseq | 0.4209 | 0.0027 | |
| SRP159526 | RNF145 | 153830 | RNAseq | -0.0189 | 0.9491 | |
| SRP193095 | RNF145 | 153830 | RNAseq | -0.0377 | 0.7931 | |
| SRP219564 | RNF145 | 153830 | RNAseq | 0.0751 | 0.8201 | |
| TCGA | RNF145 | 153830 | RNAseq | 0.1325 | 0.0078 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RNF145 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNF145:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNF145 | 153830 | 0 | 11 | 19 | |
| GSE20123 | RNF145 | 153830 | 0 | 11 | 19 | |
| GSE43470 | RNF145 | 153830 | 2 | 10 | 31 | |
| GSE46452 | RNF145 | 153830 | 0 | 27 | 32 | |
| GSE47630 | RNF145 | 153830 | 0 | 20 | 20 | |
| GSE54993 | RNF145 | 153830 | 9 | 2 | 59 | |
| GSE54994 | RNF145 | 153830 | 1 | 16 | 36 | |
| GSE60625 | RNF145 | 153830 | 0 | 0 | 11 | |
| GSE74703 | RNF145 | 153830 | 2 | 8 | 26 | |
| GSE74704 | RNF145 | 153830 | 0 | 6 | 14 | |
| TCGA | RNF145 | 153830 | 4 | 37 | 55 |
Total number of gains: 18; Total number of losses: 148; Total Number of normals: 322.
Somatic mutations of RNF145:
Generating mutation plots.
Highly correlated genes for RNF145:
Showing top 20/164 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNF145 | C5orf15 | 0.814784 | 3 | 0 | 3 |
| RNF145 | GFM2 | 0.798335 | 3 | 0 | 3 |
| RNF145 | TMEM45A | 0.793568 | 3 | 0 | 3 |
| RNF145 | SIAH1 | 0.792783 | 3 | 0 | 3 |
| RNF145 | OXA1L | 0.763668 | 3 | 0 | 3 |
| RNF145 | DDIT3 | 0.748901 | 3 | 0 | 3 |
| RNF145 | MED1 | 0.745344 | 3 | 0 | 3 |
| RNF145 | SEPSECS | 0.743451 | 3 | 0 | 3 |
| RNF145 | ANPEP | 0.737141 | 3 | 0 | 3 |
| RNF145 | PSMD12 | 0.721691 | 4 | 0 | 4 |
| RNF145 | METTL17 | 0.720358 | 3 | 0 | 3 |
| RNF145 | LTF | 0.719789 | 3 | 0 | 3 |
| RNF145 | PRKAA1 | 0.717458 | 3 | 0 | 3 |
| RNF145 | HIF1A | 0.717005 | 3 | 0 | 3 |
| RNF145 | DYNC1LI2 | 0.716955 | 4 | 0 | 3 |
| RNF145 | NUS1 | 0.714695 | 3 | 0 | 3 |
| RNF145 | ZNF830 | 0.7124 | 3 | 0 | 3 |
| RNF145 | LEPROT | 0.712078 | 3 | 0 | 3 |
| RNF145 | ATG12 | 0.712074 | 4 | 0 | 3 |
| RNF145 | RBM22 | 0.70761 | 4 | 0 | 3 |
For details and further investigation, click here
