| Full name: sorting nexin 5 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 20p11.23 | ||
| Entrez ID: 27131 | HGNC ID: HGNC:14969 | Ensembl Gene: ENSG00000089006 | OMIM ID: 605937 |
| Drug and gene relationship at DGIdb | |||
Expression of SNX5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNX5 | 27131 | 229980_s_at | 0.6282 | 0.1831 | |
| GSE20347 | SNX5 | 27131 | 217792_at | 0.3133 | 0.0296 | |
| GSE23400 | SNX5 | 27131 | 217792_at | 0.3526 | 0.0000 | |
| GSE26886 | SNX5 | 27131 | 229980_s_at | 0.7175 | 0.0000 | |
| GSE29001 | SNX5 | 27131 | 217792_at | 0.3869 | 0.1990 | |
| GSE38129 | SNX5 | 27131 | 217792_at | 0.2967 | 0.0195 | |
| GSE45670 | SNX5 | 27131 | 229980_s_at | 0.3137 | 0.0352 | |
| GSE53622 | SNX5 | 27131 | 68691 | 0.5836 | 0.0000 | |
| GSE53624 | SNX5 | 27131 | 68691 | 0.7713 | 0.0000 | |
| GSE63941 | SNX5 | 27131 | 229980_s_at | 0.6445 | 0.0247 | |
| GSE77861 | SNX5 | 27131 | 229980_s_at | 0.3682 | 0.0469 | |
| GSE97050 | SNX5 | 27131 | A_23_P131954 | 0.6575 | 0.1517 | |
| SRP007169 | SNX5 | 27131 | RNAseq | 0.2778 | 0.4092 | |
| SRP008496 | SNX5 | 27131 | RNAseq | 0.6037 | 0.0039 | |
| SRP064894 | SNX5 | 27131 | RNAseq | 0.4204 | 0.0019 | |
| SRP133303 | SNX5 | 27131 | RNAseq | 0.4319 | 0.0000 | |
| SRP159526 | SNX5 | 27131 | RNAseq | 0.5520 | 0.0538 | |
| SRP193095 | SNX5 | 27131 | RNAseq | 0.1933 | 0.0606 | |
| SRP219564 | SNX5 | 27131 | RNAseq | 0.3907 | 0.0524 | |
| TCGA | SNX5 | 27131 | RNAseq | 0.1005 | 0.0358 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SNX5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNX5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNX5 | 27131 | 12 | 3 | 15 | |
| GSE20123 | SNX5 | 27131 | 12 | 3 | 15 | |
| GSE43470 | SNX5 | 27131 | 11 | 1 | 31 | |
| GSE46452 | SNX5 | 27131 | 27 | 1 | 31 | |
| GSE47630 | SNX5 | 27131 | 17 | 4 | 19 | |
| GSE54993 | SNX5 | 27131 | 0 | 15 | 55 | |
| GSE54994 | SNX5 | 27131 | 25 | 2 | 26 | |
| GSE60625 | SNX5 | 27131 | 0 | 0 | 11 | |
| GSE74703 | SNX5 | 27131 | 8 | 1 | 27 | |
| GSE74704 | SNX5 | 27131 | 7 | 2 | 11 | |
| TCGA | SNX5 | 27131 | 43 | 10 | 43 |
Total number of gains: 162; Total number of losses: 42; Total Number of normals: 284.
Somatic mutations of SNX5:
Generating mutation plots.
Highly correlated genes for SNX5:
Showing top 20/1469 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNX5 | ARHGAP18 | 0.827121 | 3 | 0 | 3 |
| SNX5 | ROMO1 | 0.822864 | 3 | 0 | 3 |
| SNX5 | SRRD | 0.764098 | 4 | 0 | 4 |
| SNX5 | RNF152 | 0.761296 | 3 | 0 | 3 |
| SNX5 | WDR54 | 0.74546 | 5 | 0 | 5 |
| SNX5 | NOP56 | 0.74325 | 3 | 0 | 3 |
| SNX5 | SPATA2 | 0.738633 | 4 | 0 | 4 |
| SNX5 | FAM89A | 0.731372 | 3 | 0 | 3 |
| SNX5 | LMLN | 0.726676 | 3 | 0 | 3 |
| SNX5 | NUDT17 | 0.724735 | 3 | 0 | 3 |
| SNX5 | TMEM65 | 0.720737 | 3 | 0 | 3 |
| SNX5 | UEVLD | 0.715966 | 3 | 0 | 3 |
| SNX5 | TMEM63B | 0.713931 | 3 | 0 | 3 |
| SNX5 | RRP36 | 0.711817 | 4 | 0 | 4 |
| SNX5 | UTP15 | 0.709357 | 3 | 0 | 3 |
| SNX5 | SNRPB2 | 0.707477 | 12 | 0 | 11 |
| SNX5 | TOP1MT | 0.707312 | 7 | 0 | 6 |
| SNX5 | ARL6IP4 | 0.70612 | 3 | 0 | 3 |
| SNX5 | DDX60L | 0.705793 | 3 | 0 | 3 |
| SNX5 | PARVB | 0.705508 | 4 | 0 | 4 |
For details and further investigation, click here
