| Full name: lin-9 DREAM MuvB core complex component | Alias Symbol: TGS | ||
| Type: protein-coding gene | Cytoband: 1q42.12 | ||
| Entrez ID: 286826 | HGNC ID: HGNC:30830 | Ensembl Gene: ENSG00000183814 | OMIM ID: 609375 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of LIN9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LIN9 | 286826 | 235039_x_at | 0.7300 | 0.0330 | |
| GSE26886 | LIN9 | 286826 | 235039_x_at | 0.5343 | 0.0014 | |
| GSE45670 | LIN9 | 286826 | 235039_x_at | 0.5015 | 0.0008 | |
| GSE53622 | LIN9 | 286826 | 71141 | 0.5848 | 0.0000 | |
| GSE53624 | LIN9 | 286826 | 71141 | 0.9244 | 0.0000 | |
| GSE63941 | LIN9 | 286826 | 235039_x_at | 0.7213 | 0.0218 | |
| GSE77861 | LIN9 | 286826 | 235039_x_at | 0.3235 | 0.0295 | |
| GSE97050 | LIN9 | 286826 | A_32_P233304 | 0.3049 | 0.2428 | |
| SRP007169 | LIN9 | 286826 | RNAseq | 0.4237 | 0.3667 | |
| SRP008496 | LIN9 | 286826 | RNAseq | 0.9374 | 0.0164 | |
| SRP064894 | LIN9 | 286826 | RNAseq | 0.5461 | 0.0431 | |
| SRP133303 | LIN9 | 286826 | RNAseq | 1.0547 | 0.0001 | |
| SRP159526 | LIN9 | 286826 | RNAseq | 0.9004 | 0.0289 | |
| SRP193095 | LIN9 | 286826 | RNAseq | 0.4609 | 0.0008 | |
| SRP219564 | LIN9 | 286826 | RNAseq | 0.8375 | 0.0866 | |
| TCGA | LIN9 | 286826 | RNAseq | 0.4314 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by LIN9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LIN9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LIN9 | 286826 | 11 | 0 | 19 | |
| GSE20123 | LIN9 | 286826 | 11 | 0 | 19 | |
| GSE43470 | LIN9 | 286826 | 7 | 1 | 35 | |
| GSE46452 | LIN9 | 286826 | 3 | 1 | 55 | |
| GSE47630 | LIN9 | 286826 | 15 | 0 | 25 | |
| GSE54993 | LIN9 | 286826 | 0 | 6 | 64 | |
| GSE54994 | LIN9 | 286826 | 16 | 0 | 37 | |
| GSE60625 | LIN9 | 286826 | 0 | 0 | 11 | |
| GSE74703 | LIN9 | 286826 | 7 | 1 | 28 | |
| GSE74704 | LIN9 | 286826 | 5 | 0 | 15 | |
| TCGA | LIN9 | 286826 | 46 | 3 | 47 |
Total number of gains: 121; Total number of losses: 12; Total Number of normals: 355.
Somatic mutations of LIN9:
Generating mutation plots.
Highly correlated genes for LIN9:
Showing top 20/1792 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LIN9 | ZNF680 | 0.835289 | 3 | 0 | 3 |
| LIN9 | SPATA2 | 0.784332 | 3 | 0 | 3 |
| LIN9 | TTK | 0.775868 | 7 | 0 | 7 |
| LIN9 | DSCC1 | 0.771841 | 6 | 0 | 6 |
| LIN9 | SPAG5 | 0.76553 | 8 | 0 | 8 |
| LIN9 | CDCA2 | 0.765207 | 5 | 0 | 5 |
| LIN9 | FLVCR1 | 0.762115 | 7 | 0 | 7 |
| LIN9 | MMS22L | 0.759315 | 3 | 0 | 3 |
| LIN9 | BLM | 0.758209 | 8 | 0 | 8 |
| LIN9 | HJURP | 0.757138 | 7 | 0 | 7 |
| LIN9 | FZD6 | 0.755104 | 5 | 0 | 5 |
| LIN9 | BPNT1 | 0.754272 | 3 | 0 | 3 |
| LIN9 | KDM5A | 0.75248 | 3 | 0 | 3 |
| LIN9 | LRP8 | 0.749446 | 4 | 0 | 3 |
| LIN9 | RNF166 | 0.743798 | 3 | 0 | 3 |
| LIN9 | TTC39C | 0.743441 | 3 | 0 | 3 |
| LIN9 | KIF16B | 0.741358 | 3 | 0 | 3 |
| LIN9 | BORA | 0.738786 | 5 | 0 | 5 |
| LIN9 | GORAB | 0.737123 | 7 | 0 | 7 |
| LIN9 | PSMB4 | 0.736953 | 6 | 0 | 6 |
For details and further investigation, click here
