| Full name: DDHD domain containing 1 | Alias Symbol: KIAA1705|PA-PLA1 | ||
| Type: protein-coding gene | Cytoband: 14q22.1 | ||
| Entrez ID: 80821 | HGNC ID: HGNC:19714 | Ensembl Gene: ENSG00000100523 | OMIM ID: 614603 |
| Drug and gene relationship at DGIdb | |||
Expression of DDHD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DDHD1 | 80821 | 225971_at | 1.1955 | 0.0739 | |
| GSE26886 | DDHD1 | 80821 | 225971_at | 1.5302 | 0.0003 | |
| GSE45670 | DDHD1 | 80821 | 225971_at | 0.4630 | 0.2240 | |
| GSE53622 | DDHD1 | 80821 | 46203 | 1.1471 | 0.0000 | |
| GSE53624 | DDHD1 | 80821 | 46203 | 1.1856 | 0.0000 | |
| GSE63941 | DDHD1 | 80821 | 225971_at | -1.3018 | 0.0444 | |
| GSE77861 | DDHD1 | 80821 | 225965_at | 0.2675 | 0.0675 | |
| GSE97050 | DDHD1 | 80821 | A_23_P205623 | 0.4145 | 0.3221 | |
| SRP007169 | DDHD1 | 80821 | RNAseq | 2.3079 | 0.0000 | |
| SRP008496 | DDHD1 | 80821 | RNAseq | 2.6529 | 0.0000 | |
| SRP064894 | DDHD1 | 80821 | RNAseq | 0.6566 | 0.0058 | |
| SRP133303 | DDHD1 | 80821 | RNAseq | 0.3710 | 0.0053 | |
| SRP159526 | DDHD1 | 80821 | RNAseq | 0.9474 | 0.0018 | |
| SRP193095 | DDHD1 | 80821 | RNAseq | 0.6185 | 0.0000 | |
| SRP219564 | DDHD1 | 80821 | RNAseq | 0.4833 | 0.0990 | |
| TCGA | DDHD1 | 80821 | RNAseq | 0.0333 | 0.6775 |
Upregulated datasets: 5; Downregulated datasets: 1.
Survival by DDHD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DDHD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DDHD1 | 80821 | 8 | 3 | 19 | |
| GSE20123 | DDHD1 | 80821 | 8 | 3 | 19 | |
| GSE43470 | DDHD1 | 80821 | 9 | 1 | 33 | |
| GSE46452 | DDHD1 | 80821 | 16 | 3 | 40 | |
| GSE47630 | DDHD1 | 80821 | 11 | 10 | 19 | |
| GSE54993 | DDHD1 | 80821 | 3 | 8 | 59 | |
| GSE54994 | DDHD1 | 80821 | 19 | 4 | 30 | |
| GSE60625 | DDHD1 | 80821 | 0 | 2 | 9 | |
| GSE74703 | DDHD1 | 80821 | 8 | 1 | 27 | |
| GSE74704 | DDHD1 | 80821 | 3 | 2 | 15 | |
| TCGA | DDHD1 | 80821 | 34 | 12 | 50 |
Total number of gains: 119; Total number of losses: 49; Total Number of normals: 320.
Somatic mutations of DDHD1:
Generating mutation plots.
Highly correlated genes for DDHD1:
Showing top 20/1446 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DDHD1 | EPS8 | 0.789861 | 3 | 0 | 3 |
| DDHD1 | FADS1 | 0.781942 | 3 | 0 | 3 |
| DDHD1 | ZCCHC7 | 0.778417 | 3 | 0 | 3 |
| DDHD1 | NUDT15 | 0.774607 | 3 | 0 | 3 |
| DDHD1 | SRSF6 | 0.767095 | 3 | 0 | 3 |
| DDHD1 | DYNC2LI1 | 0.759586 | 3 | 0 | 3 |
| DDHD1 | TMTC1 | 0.758499 | 4 | 0 | 4 |
| DDHD1 | ZNF71 | 0.755699 | 3 | 0 | 3 |
| DDHD1 | SPATA2 | 0.751421 | 3 | 0 | 3 |
| DDHD1 | KIAA0100 | 0.749994 | 4 | 0 | 4 |
| DDHD1 | LTBR | 0.747335 | 3 | 0 | 3 |
| DDHD1 | MAP9 | 0.7424 | 3 | 0 | 3 |
| DDHD1 | SMYD3 | 0.738948 | 6 | 0 | 6 |
| DDHD1 | ZNF707 | 0.735966 | 3 | 0 | 3 |
| DDHD1 | TMEM14B | 0.735486 | 3 | 0 | 3 |
| DDHD1 | LARP6 | 0.734911 | 8 | 0 | 8 |
| DDHD1 | RBM26 | 0.73208 | 3 | 0 | 3 |
| DDHD1 | TOMM20 | 0.728496 | 4 | 0 | 4 |
| DDHD1 | RAB34 | 0.728106 | 3 | 0 | 3 |
| DDHD1 | KCNE3 | 0.7251 | 3 | 0 | 3 |
For details and further investigation, click here
