| Full name: aftiphilin | Alias Symbol: MGC33965|FLJ20080|FLJ23793|Nbla10388 | ||
| Type: protein-coding gene | Cytoband: 2p14 | ||
| Entrez ID: 54812 | HGNC ID: HGNC:25951 | Ensembl Gene: ENSG00000119844 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of AFTPH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AFTPH | 54812 | 217939_s_at | 0.0314 | 0.9518 | |
| GSE20347 | AFTPH | 54812 | 217939_s_at | -0.1338 | 0.2729 | |
| GSE23400 | AFTPH | 54812 | 217939_s_at | -0.1993 | 0.0001 | |
| GSE26886 | AFTPH | 54812 | 217939_s_at | -0.2057 | 0.4044 | |
| GSE29001 | AFTPH | 54812 | 217939_s_at | -0.4678 | 0.0638 | |
| GSE38129 | AFTPH | 54812 | 217939_s_at | -0.1151 | 0.3073 | |
| GSE45670 | AFTPH | 54812 | 217939_s_at | -0.0441 | 0.7400 | |
| GSE53622 | AFTPH | 54812 | 19266 | -0.1218 | 0.0840 | |
| GSE53624 | AFTPH | 54812 | 19266 | -0.2636 | 0.0173 | |
| GSE63941 | AFTPH | 54812 | 217939_s_at | 1.2983 | 0.0008 | |
| GSE77861 | AFTPH | 54812 | 217939_s_at | -0.0147 | 0.9456 | |
| GSE97050 | AFTPH | 54812 | A_23_P428382 | 0.2232 | 0.4552 | |
| SRP007169 | AFTPH | 54812 | RNAseq | -0.2954 | 0.3608 | |
| SRP008496 | AFTPH | 54812 | RNAseq | -0.3156 | 0.0943 | |
| SRP064894 | AFTPH | 54812 | RNAseq | -0.6044 | 0.0000 | |
| SRP133303 | AFTPH | 54812 | RNAseq | 0.0122 | 0.9244 | |
| SRP159526 | AFTPH | 54812 | RNAseq | -0.0256 | 0.8958 | |
| SRP193095 | AFTPH | 54812 | RNAseq | -0.3475 | 0.0010 | |
| SRP219564 | AFTPH | 54812 | RNAseq | -0.4563 | 0.1362 | |
| TCGA | AFTPH | 54812 | RNAseq | -0.0972 | 0.0318 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by AFTPH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AFTPH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AFTPH | 54812 | 12 | 0 | 18 | |
| GSE20123 | AFTPH | 54812 | 12 | 0 | 18 | |
| GSE43470 | AFTPH | 54812 | 7 | 0 | 36 | |
| GSE46452 | AFTPH | 54812 | 2 | 3 | 54 | |
| GSE47630 | AFTPH | 54812 | 8 | 0 | 32 | |
| GSE54993 | AFTPH | 54812 | 0 | 6 | 64 | |
| GSE54994 | AFTPH | 54812 | 12 | 0 | 41 | |
| GSE60625 | AFTPH | 54812 | 0 | 3 | 8 | |
| GSE74703 | AFTPH | 54812 | 7 | 0 | 29 | |
| GSE74704 | AFTPH | 54812 | 10 | 0 | 10 | |
| TCGA | AFTPH | 54812 | 36 | 2 | 58 |
Total number of gains: 106; Total number of losses: 14; Total Number of normals: 368.
Somatic mutations of AFTPH:
Generating mutation plots.
Highly correlated genes for AFTPH:
Showing top 20/435 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AFTPH | LMBR1 | 0.818802 | 3 | 0 | 3 |
| AFTPH | MRPL38 | 0.803784 | 3 | 0 | 3 |
| AFTPH | AAGAB | 0.773744 | 3 | 0 | 3 |
| AFTPH | SORL1 | 0.763751 | 3 | 0 | 3 |
| AFTPH | APOO | 0.762804 | 3 | 0 | 3 |
| AFTPH | C12orf50 | 0.752851 | 3 | 0 | 3 |
| AFTPH | ATP6V1G1 | 0.750999 | 3 | 0 | 3 |
| AFTPH | ARHGAP42 | 0.745704 | 3 | 0 | 3 |
| AFTPH | COPE | 0.742161 | 4 | 0 | 3 |
| AFTPH | ASCC1 | 0.738396 | 3 | 0 | 3 |
| AFTPH | ABHD2 | 0.732915 | 3 | 0 | 3 |
| AFTPH | NFIB | 0.730164 | 3 | 0 | 3 |
| AFTPH | PPP1R35 | 0.729626 | 3 | 0 | 3 |
| AFTPH | RNF207 | 0.728694 | 3 | 0 | 3 |
| AFTPH | PHB2 | 0.723212 | 3 | 0 | 3 |
| AFTPH | LRRD1 | 0.722228 | 3 | 0 | 3 |
| AFTPH | TYSND1 | 0.714343 | 4 | 0 | 3 |
| AFTPH | COX15 | 0.709745 | 5 | 0 | 4 |
| AFTPH | B4GALNT4 | 0.708816 | 3 | 0 | 3 |
| AFTPH | THRAP3 | 0.708455 | 4 | 0 | 3 |
For details and further investigation, click here
