| Full name: FLYWCH family member 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 114984 | HGNC ID: HGNC:25178 | Ensembl Gene: ENSG00000162076 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of FLYWCH2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FLYWCH2 | 114984 | 226079_at | 0.3053 | 0.1767 | |
| GSE26886 | FLYWCH2 | 114984 | 226079_at | -0.0702 | 0.6944 | |
| GSE45670 | FLYWCH2 | 114984 | 226079_at | 0.0812 | 0.5821 | |
| GSE53622 | FLYWCH2 | 114984 | 87529 | -0.0185 | 0.7990 | |
| GSE53624 | FLYWCH2 | 114984 | 87529 | 0.2754 | 0.0000 | |
| GSE63941 | FLYWCH2 | 114984 | 226079_at | -0.2351 | 0.4118 | |
| GSE77861 | FLYWCH2 | 114984 | 226079_at | -0.0930 | 0.5163 | |
| GSE97050 | FLYWCH2 | 114984 | A_24_P417596 | 0.2000 | 0.3563 | |
| SRP007169 | FLYWCH2 | 114984 | RNAseq | -0.7949 | 0.0309 | |
| SRP008496 | FLYWCH2 | 114984 | RNAseq | -0.5442 | 0.0232 | |
| SRP064894 | FLYWCH2 | 114984 | RNAseq | 0.6329 | 0.0267 | |
| SRP133303 | FLYWCH2 | 114984 | RNAseq | 0.3352 | 0.0448 | |
| SRP159526 | FLYWCH2 | 114984 | RNAseq | 0.2179 | 0.4326 | |
| SRP193095 | FLYWCH2 | 114984 | RNAseq | 0.0939 | 0.4099 | |
| SRP219564 | FLYWCH2 | 114984 | RNAseq | 0.3059 | 0.3651 | |
| TCGA | FLYWCH2 | 114984 | RNAseq | 0.1627 | 0.0213 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FLYWCH2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FLYWCH2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FLYWCH2 | 114984 | 5 | 5 | 20 | |
| GSE20123 | FLYWCH2 | 114984 | 5 | 4 | 21 | |
| GSE43470 | FLYWCH2 | 114984 | 4 | 7 | 32 | |
| GSE46452 | FLYWCH2 | 114984 | 38 | 1 | 20 | |
| GSE47630 | FLYWCH2 | 114984 | 13 | 6 | 21 | |
| GSE54993 | FLYWCH2 | 114984 | 3 | 5 | 62 | |
| GSE54994 | FLYWCH2 | 114984 | 5 | 9 | 39 | |
| GSE60625 | FLYWCH2 | 114984 | 4 | 0 | 7 | |
| GSE74703 | FLYWCH2 | 114984 | 4 | 5 | 27 | |
| GSE74704 | FLYWCH2 | 114984 | 3 | 2 | 15 | |
| TCGA | FLYWCH2 | 114984 | 19 | 13 | 64 |
Total number of gains: 103; Total number of losses: 57; Total Number of normals: 328.
Somatic mutations of FLYWCH2:
Generating mutation plots.
Highly correlated genes for FLYWCH2:
Showing top 20/166 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FLYWCH2 | NSD1 | 0.815674 | 3 | 0 | 3 |
| FLYWCH2 | KLHDC3 | 0.815601 | 3 | 0 | 3 |
| FLYWCH2 | RAB3GAP2 | 0.7929 | 3 | 0 | 3 |
| FLYWCH2 | SPSB2 | 0.787318 | 3 | 0 | 3 |
| FLYWCH2 | TBCD | 0.76914 | 3 | 0 | 3 |
| FLYWCH2 | ERGIC2 | 0.76408 | 3 | 0 | 3 |
| FLYWCH2 | PHACTR1 | 0.763279 | 3 | 0 | 3 |
| FLYWCH2 | GSK3B | 0.759099 | 3 | 0 | 3 |
| FLYWCH2 | LDLRAP1 | 0.758449 | 3 | 0 | 3 |
| FLYWCH2 | ZNF594 | 0.757247 | 3 | 0 | 3 |
| FLYWCH2 | POU3F4 | 0.755614 | 3 | 0 | 3 |
| FLYWCH2 | GIT1 | 0.75095 | 3 | 0 | 3 |
| FLYWCH2 | ZBTB10 | 0.749574 | 3 | 0 | 3 |
| FLYWCH2 | MFSD3 | 0.745598 | 3 | 0 | 3 |
| FLYWCH2 | FCHO1 | 0.739041 | 3 | 0 | 3 |
| FLYWCH2 | UBE3B | 0.730536 | 3 | 0 | 3 |
| FLYWCH2 | PSKH1 | 0.7301 | 3 | 0 | 3 |
| FLYWCH2 | MUL1 | 0.728798 | 4 | 0 | 4 |
| FLYWCH2 | CENPBD1 | 0.727899 | 3 | 0 | 3 |
| FLYWCH2 | POLN | 0.726329 | 3 | 0 | 3 |
For details and further investigation, click here
