| Full name: collagen type XI alpha 2 chain | Alias Symbol: HKE5 | ||
| Type: protein-coding gene | Cytoband: 6p21.32 | ||
| Entrez ID: 1302 | HGNC ID: HGNC:2187 | Ensembl Gene: ENSG00000204248 | OMIM ID: 120290 |
| Drug and gene relationship at DGIdb | |||
Expression of COL11A2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COL11A2 | 1302 | 216993_s_at | 0.0488 | 0.8557 | |
| GSE20347 | COL11A2 | 1302 | 216993_s_at | 0.0768 | 0.3254 | |
| GSE23400 | COL11A2 | 1302 | 216993_s_at | 0.0182 | 0.6543 | |
| GSE26886 | COL11A2 | 1302 | 216993_s_at | 0.2162 | 0.0387 | |
| GSE29001 | COL11A2 | 1302 | 213870_at | -0.0431 | 0.8565 | |
| GSE38129 | COL11A2 | 1302 | 216993_s_at | -0.0208 | 0.8694 | |
| GSE45670 | COL11A2 | 1302 | 216993_s_at | 0.1142 | 0.1747 | |
| GSE53622 | COL11A2 | 1302 | 39177 | 0.1867 | 0.0280 | |
| GSE53624 | COL11A2 | 1302 | 39177 | 0.0016 | 0.9905 | |
| GSE63941 | COL11A2 | 1302 | 216993_s_at | 0.1871 | 0.2752 | |
| GSE77861 | COL11A2 | 1302 | 216993_s_at | 0.0214 | 0.8741 | |
| GSE97050 | COL11A2 | 1302 | A_33_P3216442 | -0.1289 | 0.6457 | |
| SRP064894 | COL11A2 | 1302 | RNAseq | 0.3289 | 0.1375 | |
| SRP133303 | COL11A2 | 1302 | RNAseq | 0.5457 | 0.1727 | |
| SRP219564 | COL11A2 | 1302 | RNAseq | 0.6368 | 0.2188 | |
| TCGA | COL11A2 | 1302 | RNAseq | 0.7076 | 0.0526 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by COL11A2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COL11A2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COL11A2 | 1302 | 5 | 0 | 25 | |
| GSE20123 | COL11A2 | 1302 | 5 | 0 | 25 | |
| GSE43470 | COL11A2 | 1302 | 4 | 1 | 38 | |
| GSE46452 | COL11A2 | 1302 | 2 | 9 | 48 | |
| GSE47630 | COL11A2 | 1302 | 8 | 4 | 28 | |
| GSE54993 | COL11A2 | 1302 | 3 | 1 | 66 | |
| GSE54994 | COL11A2 | 1302 | 11 | 4 | 38 | |
| GSE60625 | COL11A2 | 1302 | 1 | 0 | 10 | |
| GSE74703 | COL11A2 | 1302 | 4 | 0 | 32 | |
| GSE74704 | COL11A2 | 1302 | 2 | 0 | 18 | |
| TCGA | COL11A2 | 1302 | 15 | 16 | 65 |
Total number of gains: 60; Total number of losses: 35; Total Number of normals: 393.
Somatic mutations of COL11A2:
Generating mutation plots.
Highly correlated genes for COL11A2:
Showing top 20/772 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COL11A2 | KRTAP12-2 | 0.794414 | 4 | 0 | 3 |
| COL11A2 | KRTAP10-9 | 0.778145 | 3 | 0 | 3 |
| COL11A2 | ALG11 | 0.776577 | 3 | 0 | 3 |
| COL11A2 | ARL17A | 0.763123 | 3 | 0 | 3 |
| COL11A2 | OR2T33 | 0.747993 | 4 | 0 | 4 |
| COL11A2 | KIR3DL2 | 0.736168 | 3 | 0 | 3 |
| COL11A2 | CASC2 | 0.735554 | 4 | 0 | 4 |
| COL11A2 | SENP1 | 0.733847 | 3 | 0 | 3 |
| COL11A2 | SPEG | 0.72783 | 4 | 0 | 4 |
| COL11A2 | TIGD1 | 0.727182 | 4 | 0 | 4 |
| COL11A2 | ZNF358 | 0.713867 | 4 | 0 | 4 |
| COL11A2 | KLHL33 | 0.711213 | 3 | 0 | 3 |
| COL11A2 | HCG18 | 0.710412 | 3 | 0 | 3 |
| COL11A2 | LMLN | 0.706019 | 3 | 0 | 3 |
| COL11A2 | SPDYE5 | 0.704351 | 3 | 0 | 3 |
| COL11A2 | OR2AT4 | 0.703876 | 3 | 0 | 3 |
| COL11A2 | ARHGAP39 | 0.703234 | 3 | 0 | 3 |
| COL11A2 | TCF23 | 0.702956 | 3 | 0 | 3 |
| COL11A2 | GAD2 | 0.70277 | 4 | 0 | 4 |
| COL11A2 | POLH | 0.701633 | 3 | 0 | 3 |
For details and further investigation, click here
