| Full name: family with sequence similarity 170 member A | Alias Symbol: ZNFD | ||
| Type: protein-coding gene | Cytoband: 5q23.1 | ||
| Entrez ID: 340069 | HGNC ID: HGNC:27963 | Ensembl Gene: ENSG00000164334 | OMIM ID: 618401 |
| Drug and gene relationship at DGIdb | |||
Expression of FAM170A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM170A | 340069 | 1562906_at | -0.1992 | 0.4079 | |
| GSE26886 | FAM170A | 340069 | 1562906_at | -0.2938 | 0.0313 | |
| GSE45670 | FAM170A | 340069 | 1562906_at | 0.0897 | 0.5209 | |
| GSE53622 | FAM170A | 340069 | 37974 | -0.0745 | 0.2760 | |
| GSE53624 | FAM170A | 340069 | 37974 | -0.1274 | 0.0305 | |
| GSE63941 | FAM170A | 340069 | 1562906_at | 0.2070 | 0.2307 | |
| GSE77861 | FAM170A | 340069 | 1562906_at | -0.3219 | 0.0650 | |
| TCGA | FAM170A | 340069 | RNAseq | 0.3384 | 0.8156 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FAM170A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM170A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM170A | 340069 | 1 | 13 | 16 | |
| GSE20123 | FAM170A | 340069 | 1 | 13 | 16 | |
| GSE43470 | FAM170A | 340069 | 5 | 6 | 32 | |
| GSE46452 | FAM170A | 340069 | 0 | 27 | 32 | |
| GSE47630 | FAM170A | 340069 | 0 | 21 | 19 | |
| GSE54993 | FAM170A | 340069 | 9 | 1 | 60 | |
| GSE54994 | FAM170A | 340069 | 2 | 14 | 37 | |
| GSE60625 | FAM170A | 340069 | 0 | 0 | 11 | |
| GSE74703 | FAM170A | 340069 | 3 | 5 | 28 | |
| GSE74704 | FAM170A | 340069 | 1 | 7 | 12 | |
| TCGA | FAM170A | 340069 | 2 | 42 | 52 |
Total number of gains: 24; Total number of losses: 149; Total Number of normals: 315.
Somatic mutations of FAM170A:
Generating mutation plots.
Highly correlated genes for FAM170A:
Showing top 20/149 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM170A | ARPC2 | 0.759524 | 3 | 0 | 3 |
| FAM170A | PRR29 | 0.706472 | 3 | 0 | 3 |
| FAM170A | ANXA1 | 0.68784 | 3 | 0 | 3 |
| FAM170A | PHF7 | 0.674871 | 3 | 0 | 3 |
| FAM170A | BHLHE40 | 0.674698 | 3 | 0 | 3 |
| FAM170A | NMU | 0.671696 | 3 | 0 | 3 |
| FAM170A | SPATA21 | 0.671103 | 3 | 0 | 3 |
| FAM170A | LRP10 | 0.670793 | 3 | 0 | 3 |
| FAM170A | TMEM242 | 0.669279 | 3 | 0 | 3 |
| FAM170A | VAV3 | 0.668426 | 3 | 0 | 3 |
| FAM170A | ADORA1 | 0.667272 | 3 | 0 | 3 |
| FAM170A | DLG2 | 0.660499 | 3 | 0 | 3 |
| FAM170A | HCAR3 | 0.659675 | 4 | 0 | 4 |
| FAM170A | DPPA4 | 0.659306 | 3 | 0 | 3 |
| FAM170A | CHRNA4 | 0.657721 | 3 | 0 | 3 |
| FAM170A | CLCA4 | 0.651911 | 3 | 0 | 3 |
| FAM170A | PLEKHN1 | 0.649822 | 3 | 0 | 3 |
| FAM170A | LMAN2 | 0.646722 | 3 | 0 | 3 |
| FAM170A | ADIG | 0.642323 | 4 | 0 | 3 |
| FAM170A | CARHSP1 | 0.6417 | 4 | 0 | 4 |
For details and further investigation, click here
