| Full name: Janus kinase and microtubule interacting protein 3 | Alias Symbol: FLJ37857|NECC2|KIAA4091|bA140A10.5 | ||
| Type: protein-coding gene | Cytoband: 10q26.3 | ||
| Entrez ID: 282973 | HGNC ID: HGNC:23523 | Ensembl Gene: ENSG00000188385 | OMIM ID: 611198 |
| Drug and gene relationship at DGIdb | |||
Expression of JAKMIP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | JAKMIP3 | 282973 | 233076_at | 0.2920 | 0.7336 | |
| GSE26886 | JAKMIP3 | 282973 | 233076_at | 1.0082 | 0.0041 | |
| GSE45670 | JAKMIP3 | 282973 | 233076_at | 0.4040 | 0.3021 | |
| GSE53622 | JAKMIP3 | 282973 | 7491 | 0.9204 | 0.0038 | |
| GSE53624 | JAKMIP3 | 282973 | 7491 | 1.3359 | 0.0000 | |
| GSE63941 | JAKMIP3 | 282973 | 233076_at | 0.2216 | 0.6970 | |
| GSE77861 | JAKMIP3 | 282973 | 233076_at | 0.1987 | 0.1094 | |
| GSE97050 | JAKMIP3 | 282973 | A_24_P332081 | -0.3643 | 0.3379 | |
| SRP133303 | JAKMIP3 | 282973 | RNAseq | 1.3248 | 0.0024 | |
| SRP159526 | JAKMIP3 | 282973 | RNAseq | 3.4362 | 0.0000 | |
| SRP219564 | JAKMIP3 | 282973 | RNAseq | 0.5591 | 0.4654 | |
| TCGA | JAKMIP3 | 282973 | RNAseq | 0.1179 | 0.7860 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by JAKMIP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of JAKMIP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | JAKMIP3 | 282973 | 2 | 8 | 20 | |
| GSE20123 | JAKMIP3 | 282973 | 2 | 9 | 19 | |
| GSE43470 | JAKMIP3 | 282973 | 1 | 9 | 33 | |
| GSE46452 | JAKMIP3 | 282973 | 1 | 11 | 47 | |
| GSE47630 | JAKMIP3 | 282973 | 4 | 13 | 23 | |
| GSE54993 | JAKMIP3 | 282973 | 7 | 1 | 62 | |
| GSE54994 | JAKMIP3 | 282973 | 1 | 9 | 43 | |
| GSE60625 | JAKMIP3 | 282973 | 0 | 0 | 11 | |
| GSE74703 | JAKMIP3 | 282973 | 0 | 6 | 30 | |
| GSE74704 | JAKMIP3 | 282973 | 2 | 4 | 14 | |
| TCGA | JAKMIP3 | 282973 | 7 | 28 | 61 |
Total number of gains: 27; Total number of losses: 98; Total Number of normals: 363.
Somatic mutations of JAKMIP3:
Generating mutation plots.
Highly correlated genes for JAKMIP3:
Showing top 20/196 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| JAKMIP3 | SV2B | 0.878428 | 3 | 0 | 3 |
| JAKMIP3 | SPRED3 | 0.81368 | 3 | 0 | 3 |
| JAKMIP3 | TMEM116 | 0.784379 | 3 | 0 | 3 |
| JAKMIP3 | TATDN3 | 0.752456 | 3 | 0 | 3 |
| JAKMIP3 | DLX6-AS1 | 0.752345 | 3 | 0 | 3 |
| JAKMIP3 | KIRREL2 | 0.750737 | 3 | 0 | 3 |
| JAKMIP3 | TMCC2 | 0.748494 | 5 | 0 | 4 |
| JAKMIP3 | DHX9 | 0.728476 | 3 | 0 | 3 |
| JAKMIP3 | CNTD2 | 0.725585 | 3 | 0 | 3 |
| JAKMIP3 | C19orf53 | 0.722268 | 3 | 0 | 3 |
| JAKMIP3 | STAC2 | 0.720121 | 3 | 0 | 3 |
| JAKMIP3 | HSD17B3 | 0.720046 | 3 | 0 | 3 |
| JAKMIP3 | ANGPT4 | 0.719999 | 3 | 0 | 3 |
| JAKMIP3 | LRRC3 | 0.718235 | 3 | 0 | 3 |
| JAKMIP3 | MRPS2 | 0.715203 | 5 | 0 | 5 |
| JAKMIP3 | KLHL26 | 0.714927 | 3 | 0 | 3 |
| JAKMIP3 | DRG2 | 0.709449 | 3 | 0 | 3 |
| JAKMIP3 | CIB3 | 0.70557 | 3 | 0 | 3 |
| JAKMIP3 | SOX2-OT | 0.701861 | 4 | 0 | 3 |
| JAKMIP3 | TSSK3 | 0.696782 | 3 | 0 | 3 |
For details and further investigation, click here
