| Full name: SRC kinase signaling inhibitor 1 | Alias Symbol: SNIP|p140Cap|KIAA1684 | ||
| Type: protein-coding gene | Cytoband: 17q12 | ||
| Entrez ID: 80725 | HGNC ID: HGNC:29506 | Ensembl Gene: ENSG00000277363 | OMIM ID: 610786 |
| Drug and gene relationship at DGIdb | |||
Expression of SRCIN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SRCIN1 | 80725 | 1554759_at | -0.1368 | 0.5409 | |
| GSE26886 | SRCIN1 | 80725 | 1554759_at | -0.1925 | 0.0592 | |
| GSE45670 | SRCIN1 | 80725 | 1554759_at | -0.0906 | 0.2739 | |
| GSE53622 | SRCIN1 | 80725 | 39633 | 0.1125 | 0.1603 | |
| GSE53624 | SRCIN1 | 80725 | 39633 | 0.0936 | 0.2335 | |
| GSE63941 | SRCIN1 | 80725 | 1554759_at | 0.2407 | 0.0854 | |
| GSE77861 | SRCIN1 | 80725 | 1554759_at | -0.0575 | 0.6955 | |
| GSE97050 | SRCIN1 | 80725 | A_33_P3404844 | -0.1347 | 0.6083 | |
| SRP133303 | SRCIN1 | 80725 | RNAseq | 0.5747 | 0.2449 | |
| SRP159526 | SRCIN1 | 80725 | RNAseq | 0.9261 | 0.0930 | |
| SRP219564 | SRCIN1 | 80725 | RNAseq | 0.6773 | 0.2731 | |
| TCGA | SRCIN1 | 80725 | RNAseq | -0.2747 | 0.1003 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SRCIN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SRCIN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SRCIN1 | 80725 | 7 | 1 | 22 | |
| GSE20123 | SRCIN1 | 80725 | 7 | 1 | 22 | |
| GSE43470 | SRCIN1 | 80725 | 0 | 1 | 42 | |
| GSE46452 | SRCIN1 | 80725 | 34 | 0 | 25 | |
| GSE47630 | SRCIN1 | 80725 | 8 | 1 | 31 | |
| GSE54993 | SRCIN1 | 80725 | 3 | 4 | 63 | |
| GSE54994 | SRCIN1 | 80725 | 8 | 5 | 40 | |
| GSE60625 | SRCIN1 | 80725 | 4 | 0 | 7 | |
| GSE74703 | SRCIN1 | 80725 | 0 | 0 | 36 | |
| GSE74704 | SRCIN1 | 80725 | 4 | 1 | 15 | |
| TCGA | SRCIN1 | 80725 | 19 | 9 | 68 |
Total number of gains: 94; Total number of losses: 23; Total Number of normals: 371.
Somatic mutations of SRCIN1:
Generating mutation plots.
Highly correlated genes for SRCIN1:
Showing top 20/405 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SRCIN1 | ZAN | 0.80785 | 3 | 0 | 3 |
| SRCIN1 | YY2 | 0.774324 | 3 | 0 | 3 |
| SRCIN1 | ABCA4 | 0.757791 | 3 | 0 | 3 |
| SRCIN1 | BBC3 | 0.757504 | 3 | 0 | 3 |
| SRCIN1 | PRSS38 | 0.756025 | 3 | 0 | 3 |
| SRCIN1 | SLC25A48 | 0.753578 | 3 | 0 | 3 |
| SRCIN1 | ANKRD33B | 0.751585 | 4 | 0 | 4 |
| SRCIN1 | SSTR2 | 0.743901 | 3 | 0 | 3 |
| SRCIN1 | C1QL2 | 0.739642 | 3 | 0 | 3 |
| SRCIN1 | OR2B11 | 0.739188 | 3 | 0 | 3 |
| SRCIN1 | KLHL10 | 0.736745 | 3 | 0 | 3 |
| SRCIN1 | INSC | 0.728861 | 3 | 0 | 3 |
| SRCIN1 | OR2D2 | 0.725815 | 3 | 0 | 3 |
| SRCIN1 | MRGPRG | 0.723066 | 3 | 0 | 3 |
| SRCIN1 | GRIK4 | 0.720853 | 3 | 0 | 3 |
| SRCIN1 | TOR2A | 0.720463 | 3 | 0 | 3 |
| SRCIN1 | C9orf153 | 0.719608 | 3 | 0 | 3 |
| SRCIN1 | KRTAP2-1 | 0.719081 | 4 | 0 | 4 |
| SRCIN1 | BSX | 0.719072 | 3 | 0 | 3 |
| SRCIN1 | DCDC1 | 0.71845 | 3 | 0 | 3 |
For details and further investigation, click here
