| Full name: chromosome 19 open reading frame 57 | Alias Symbol: MGC11271 | ||
| Type: protein-coding gene | Cytoband: 19p13.12 | ||
| Entrez ID: 79173 | HGNC ID: HGNC:28153 | Ensembl Gene: ENSG00000132016 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C19orf57:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C19orf57 | 79173 | 206901_at | -0.0918 | 0.7427 | |
| GSE20347 | C19orf57 | 79173 | 206901_at | -0.0302 | 0.7166 | |
| GSE23400 | C19orf57 | 79173 | 206901_at | -0.1615 | 0.0004 | |
| GSE26886 | C19orf57 | 79173 | 206901_at | 0.1938 | 0.0612 | |
| GSE29001 | C19orf57 | 79173 | 206901_at | 0.0411 | 0.8135 | |
| GSE38129 | C19orf57 | 79173 | 206901_at | -0.0665 | 0.4201 | |
| GSE45670 | C19orf57 | 79173 | 206901_at | -0.0144 | 0.9035 | |
| GSE53622 | C19orf57 | 79173 | 57007 | -2.9397 | 0.0000 | |
| GSE53624 | C19orf57 | 79173 | 57007 | -2.6727 | 0.0000 | |
| GSE63941 | C19orf57 | 79173 | 206901_at | 0.3030 | 0.0591 | |
| GSE77861 | C19orf57 | 79173 | 206901_at | 0.0049 | 0.9675 | |
| GSE97050 | C19orf57 | 79173 | A_23_P164814 | -0.9679 | 0.1399 | |
| SRP064894 | C19orf57 | 79173 | RNAseq | 0.5453 | 0.1772 | |
| SRP133303 | C19orf57 | 79173 | RNAseq | -0.1118 | 0.7784 | |
| SRP193095 | C19orf57 | 79173 | RNAseq | -0.6569 | 0.0012 | |
| SRP219564 | C19orf57 | 79173 | RNAseq | 0.4161 | 0.5585 | |
| TCGA | C19orf57 | 79173 | RNAseq | 0.3522 | 0.0421 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by C19orf57 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C19orf57:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C19orf57 | 79173 | 4 | 2 | 24 | |
| GSE20123 | C19orf57 | 79173 | 3 | 1 | 26 | |
| GSE43470 | C19orf57 | 79173 | 2 | 6 | 35 | |
| GSE46452 | C19orf57 | 79173 | 47 | 1 | 11 | |
| GSE47630 | C19orf57 | 79173 | 4 | 7 | 29 | |
| GSE54993 | C19orf57 | 79173 | 15 | 4 | 51 | |
| GSE54994 | C19orf57 | 79173 | 6 | 13 | 34 | |
| GSE60625 | C19orf57 | 79173 | 9 | 0 | 2 | |
| GSE74703 | C19orf57 | 79173 | 2 | 4 | 30 | |
| GSE74704 | C19orf57 | 79173 | 0 | 1 | 19 | |
| TCGA | C19orf57 | 79173 | 21 | 11 | 64 |
Total number of gains: 113; Total number of losses: 50; Total Number of normals: 325.
Somatic mutations of C19orf57:
Generating mutation plots.
Highly correlated genes for C19orf57:
Showing top 20/581 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C19orf57 | NCCRP1 | 0.926046 | 3 | 0 | 3 |
| C19orf57 | TMPRSS11A | 0.897984 | 3 | 0 | 3 |
| C19orf57 | SPRR2F | 0.860174 | 3 | 0 | 3 |
| C19orf57 | SPATA19 | 0.859313 | 3 | 0 | 3 |
| C19orf57 | CSTL1 | 0.846207 | 3 | 0 | 3 |
| C19orf57 | SPRR2E | 0.842202 | 3 | 0 | 3 |
| C19orf57 | SPRR2D | 0.829069 | 3 | 0 | 3 |
| C19orf57 | SPRR2A | 0.821057 | 3 | 0 | 3 |
| C19orf57 | OTOP3 | 0.817965 | 3 | 0 | 3 |
| C19orf57 | UPK3B | 0.806832 | 3 | 0 | 3 |
| C19orf57 | PHF12 | 0.80442 | 3 | 0 | 3 |
| C19orf57 | SPRR2B | 0.791766 | 3 | 0 | 3 |
| C19orf57 | RNF222 | 0.787449 | 3 | 0 | 3 |
| C19orf57 | TECPR1 | 0.761384 | 3 | 0 | 3 |
| C19orf57 | MUC22 | 0.761292 | 3 | 0 | 3 |
| C19orf57 | ARHGAP40 | 0.759453 | 3 | 0 | 3 |
| C19orf57 | OR2Z1 | 0.752559 | 3 | 0 | 3 |
| C19orf57 | ST3GAL3 | 0.752492 | 3 | 0 | 3 |
| C19orf57 | SDCBP2 | 0.750959 | 3 | 0 | 3 |
| C19orf57 | MFSD2B | 0.750498 | 3 | 0 | 3 |
For details and further investigation, click here
