| Full name: suppression of tumorigenicity 5 | Alias Symbol: HTS1|DENND2B|p126 | ||
| Type: protein-coding gene | Cytoband: 11p15.4 | ||
| Entrez ID: 6764 | HGNC ID: HGNC:11350 | Ensembl Gene: ENSG00000166444 | OMIM ID: 140750 |
| Drug and gene relationship at DGIdb | |||
Expression of ST5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ST5 | 6764 | 202440_s_at | -0.9147 | 0.1013 | |
| GSE20347 | ST5 | 6764 | 202440_s_at | -0.7502 | 0.0000 | |
| GSE23400 | ST5 | 6764 | 202440_s_at | -0.6189 | 0.0000 | |
| GSE26886 | ST5 | 6764 | 202440_s_at | -0.7473 | 0.0319 | |
| GSE29001 | ST5 | 6764 | 202440_s_at | -0.3409 | 0.3092 | |
| GSE38129 | ST5 | 6764 | 202440_s_at | -0.8377 | 0.0000 | |
| GSE45670 | ST5 | 6764 | 202440_s_at | -0.0800 | 0.7428 | |
| GSE53622 | ST5 | 6764 | 37246 | -0.4327 | 0.0002 | |
| GSE53624 | ST5 | 6764 | 37246 | -0.2845 | 0.0081 | |
| GSE63941 | ST5 | 6764 | 202440_s_at | -1.1860 | 0.0820 | |
| GSE77861 | ST5 | 6764 | 202440_s_at | -0.4981 | 0.1543 | |
| GSE97050 | ST5 | 6764 | A_23_P24884 | -0.5710 | 0.1859 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ST5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ST5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ST5 | 6764 | 0 | 10 | 20 | |
| GSE20123 | ST5 | 6764 | 0 | 10 | 20 | |
| GSE43470 | ST5 | 6764 | 1 | 7 | 35 | |
| GSE46452 | ST5 | 6764 | 7 | 5 | 47 | |
| GSE47630 | ST5 | 6764 | 2 | 12 | 26 | |
| GSE54993 | ST5 | 6764 | 3 | 1 | 66 | |
| GSE54994 | ST5 | 6764 | 2 | 12 | 39 | |
| GSE60625 | ST5 | 6764 | 0 | 0 | 11 | |
| GSE74703 | ST5 | 6764 | 1 | 5 | 30 | |
| GSE74704 | ST5 | 6764 | 0 | 8 | 12 | |
| TCGA | ST5 | 6764 | 11 | 34 | 51 |
Total number of gains: 27; Total number of losses: 104; Total Number of normals: 357.
Somatic mutations of ST5:
Generating mutation plots.
Highly correlated genes for ST5:
Showing top 20/662 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ST5 | SOX7 | 0.777802 | 3 | 0 | 3 |
| ST5 | NUDCD3 | 0.727305 | 4 | 0 | 4 |
| ST5 | AKIP1 | 0.723927 | 5 | 0 | 4 |
| ST5 | MTIF3 | 0.720979 | 3 | 0 | 3 |
| ST5 | IGSF10 | 0.713041 | 3 | 0 | 3 |
| ST5 | KCTD21 | 0.708834 | 3 | 0 | 3 |
| ST5 | GTF3C6 | 0.70334 | 3 | 0 | 3 |
| ST5 | IBTK | 0.695739 | 4 | 0 | 3 |
| ST5 | SPATS2L | 0.690401 | 3 | 0 | 3 |
| ST5 | CPEB2 | 0.687715 | 4 | 0 | 4 |
| ST5 | PYGM | 0.686873 | 6 | 0 | 5 |
| ST5 | JDP2 | 0.684392 | 4 | 0 | 3 |
| ST5 | ZNF844 | 0.670979 | 3 | 0 | 3 |
| ST5 | TCEAL2 | 0.664192 | 3 | 0 | 3 |
| ST5 | RDX | 0.66393 | 4 | 0 | 3 |
| ST5 | KLHDC8B | 0.663521 | 5 | 0 | 4 |
| ST5 | SLC35A1 | 0.663297 | 4 | 0 | 3 |
| ST5 | PBXIP1 | 0.661171 | 6 | 0 | 5 |
| ST5 | HOXA4 | 0.658623 | 7 | 0 | 5 |
| ST5 | TRIM6 | 0.657827 | 6 | 0 | 5 |
For details and further investigation, click here
