| Full name: NudC domain containing 3 | Alias Symbol: KIAA1068|NudCL | ||
| Type: protein-coding gene | Cytoband: 7p13 | ||
| Entrez ID: 23386 | HGNC ID: HGNC:22208 | Ensembl Gene: ENSG00000015676 | OMIM ID: 610296 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NUDCD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NUDCD3 | 23386 | 201270_x_at | 0.0131 | 0.9714 | |
| GSE20347 | NUDCD3 | 23386 | 201270_x_at | 0.0345 | 0.7649 | |
| GSE23400 | NUDCD3 | 23386 | 201270_x_at | -0.0379 | 0.4676 | |
| GSE26886 | NUDCD3 | 23386 | 201270_x_at | -0.2876 | 0.0531 | |
| GSE29001 | NUDCD3 | 23386 | 201270_x_at | -0.0674 | 0.7862 | |
| GSE38129 | NUDCD3 | 23386 | 201270_x_at | 0.0405 | 0.6681 | |
| GSE45670 | NUDCD3 | 23386 | 201270_x_at | 0.0620 | 0.6441 | |
| GSE53622 | NUDCD3 | 23386 | 78091 | -0.0496 | 0.3140 | |
| GSE53624 | NUDCD3 | 23386 | 78091 | 0.0321 | 0.5832 | |
| GSE63941 | NUDCD3 | 23386 | 201270_x_at | 0.0461 | 0.9259 | |
| GSE77861 | NUDCD3 | 23386 | 201270_x_at | -0.0455 | 0.7930 | |
| GSE97050 | NUDCD3 | 23386 | A_23_P31477 | -0.1768 | 0.5029 | |
| SRP007169 | NUDCD3 | 23386 | RNAseq | -1.1227 | 0.0002 | |
| SRP008496 | NUDCD3 | 23386 | RNAseq | -0.6160 | 0.0277 | |
| SRP064894 | NUDCD3 | 23386 | RNAseq | 0.0937 | 0.5618 | |
| SRP133303 | NUDCD3 | 23386 | RNAseq | -0.1079 | 0.4770 | |
| SRP159526 | NUDCD3 | 23386 | RNAseq | -0.0791 | 0.7199 | |
| SRP193095 | NUDCD3 | 23386 | RNAseq | -0.0794 | 0.3964 | |
| SRP219564 | NUDCD3 | 23386 | RNAseq | -0.1668 | 0.5291 | |
| TCGA | NUDCD3 | 23386 | RNAseq | -0.0102 | 0.8220 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by NUDCD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NUDCD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NUDCD3 | 23386 | 14 | 0 | 16 | |
| GSE20123 | NUDCD3 | 23386 | 13 | 0 | 17 | |
| GSE43470 | NUDCD3 | 23386 | 4 | 0 | 39 | |
| GSE46452 | NUDCD3 | 23386 | 11 | 1 | 47 | |
| GSE47630 | NUDCD3 | 23386 | 8 | 1 | 31 | |
| GSE54993 | NUDCD3 | 23386 | 0 | 8 | 62 | |
| GSE54994 | NUDCD3 | 23386 | 17 | 3 | 33 | |
| GSE60625 | NUDCD3 | 23386 | 0 | 0 | 11 | |
| GSE74703 | NUDCD3 | 23386 | 4 | 0 | 32 | |
| GSE74704 | NUDCD3 | 23386 | 7 | 0 | 13 | |
| TCGA | NUDCD3 | 23386 | 50 | 7 | 39 |
Total number of gains: 128; Total number of losses: 20; Total Number of normals: 340.
Somatic mutations of NUDCD3:
Generating mutation plots.
Highly correlated genes for NUDCD3:
Showing top 20/124 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NUDCD3 | IQGAP1 | 0.806499 | 3 | 0 | 3 |
| NUDCD3 | ENOSF1 | 0.776655 | 3 | 0 | 3 |
| NUDCD3 | NIPAL3 | 0.7679 | 3 | 0 | 3 |
| NUDCD3 | ALG9 | 0.764768 | 3 | 0 | 3 |
| NUDCD3 | TTC23 | 0.763277 | 3 | 0 | 3 |
| NUDCD3 | SYNE2 | 0.734285 | 3 | 0 | 3 |
| NUDCD3 | ST5 | 0.727305 | 4 | 0 | 4 |
| NUDCD3 | LNX2 | 0.721406 | 3 | 0 | 3 |
| NUDCD3 | MPHOSPH8 | 0.713852 | 3 | 0 | 3 |
| NUDCD3 | RBM5 | 0.712815 | 4 | 0 | 3 |
| NUDCD3 | EPC1 | 0.702337 | 3 | 0 | 3 |
| NUDCD3 | MAP4K5 | 0.696606 | 3 | 0 | 3 |
| NUDCD3 | JAK1 | 0.695313 | 3 | 0 | 3 |
| NUDCD3 | KIF13B | 0.693862 | 3 | 0 | 3 |
| NUDCD3 | PRKAB1 | 0.690455 | 3 | 0 | 3 |
| NUDCD3 | LIN7B | 0.68203 | 3 | 0 | 3 |
| NUDCD3 | COBL | 0.678729 | 3 | 0 | 3 |
| NUDCD3 | BARD1 | 0.670611 | 3 | 0 | 3 |
| NUDCD3 | WDR37 | 0.66854 | 3 | 0 | 3 |
| NUDCD3 | SLC7A1 | 0.662522 | 4 | 0 | 4 |
For details and further investigation, click here
