| Full name: cytoplasmic polyadenylation element binding protein 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4p15.32 | ||
| Entrez ID: 132864 | HGNC ID: HGNC:21745 | Ensembl Gene: ENSG00000137449 | OMIM ID: 610605 |
| Drug and gene relationship at DGIdb | |||
CPEB2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04114 | Oocyte meiosis |
Expression of CPEB2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CPEB2 | 132864 | 226939_at | -0.6007 | 0.3862 | |
| GSE26886 | CPEB2 | 132864 | 226939_at | -1.1712 | 0.0003 | |
| GSE45670 | CPEB2 | 132864 | 226939_at | -0.3414 | 0.1658 | |
| GSE53622 | CPEB2 | 132864 | 82451 | -1.1269 | 0.0000 | |
| GSE53624 | CPEB2 | 132864 | 82451 | -1.4445 | 0.0000 | |
| GSE63941 | CPEB2 | 132864 | 226939_at | -2.2838 | 0.0284 | |
| GSE77861 | CPEB2 | 132864 | 226939_at | -0.9089 | 0.0196 | |
| GSE97050 | CPEB2 | 132864 | A_32_P225355 | -0.6270 | 0.2144 | |
| SRP007169 | CPEB2 | 132864 | RNAseq | -1.6275 | 0.0004 | |
| SRP008496 | CPEB2 | 132864 | RNAseq | -1.7461 | 0.0000 | |
| SRP064894 | CPEB2 | 132864 | RNAseq | -1.5180 | 0.0000 | |
| SRP133303 | CPEB2 | 132864 | RNAseq | -0.9767 | 0.0000 | |
| SRP159526 | CPEB2 | 132864 | RNAseq | -1.6264 | 0.0000 | |
| SRP193095 | CPEB2 | 132864 | RNAseq | -1.3759 | 0.0000 | |
| SRP219564 | CPEB2 | 132864 | RNAseq | -0.8759 | 0.0376 | |
| TCGA | CPEB2 | 132864 | RNAseq | -0.2853 | 0.0018 |
Upregulated datasets: 0; Downregulated datasets: 9.
Survival by CPEB2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CPEB2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CPEB2 | 132864 | 0 | 18 | 12 | |
| GSE20123 | CPEB2 | 132864 | 0 | 18 | 12 | |
| GSE43470 | CPEB2 | 132864 | 1 | 15 | 27 | |
| GSE46452 | CPEB2 | 132864 | 1 | 36 | 22 | |
| GSE47630 | CPEB2 | 132864 | 0 | 20 | 20 | |
| GSE54993 | CPEB2 | 132864 | 10 | 0 | 60 | |
| GSE54994 | CPEB2 | 132864 | 4 | 12 | 37 | |
| GSE60625 | CPEB2 | 132864 | 0 | 0 | 11 | |
| GSE74703 | CPEB2 | 132864 | 1 | 13 | 22 | |
| GSE74704 | CPEB2 | 132864 | 0 | 11 | 9 | |
| TCGA | CPEB2 | 132864 | 9 | 48 | 39 |
Total number of gains: 26; Total number of losses: 191; Total Number of normals: 271.
Somatic mutations of CPEB2:
Generating mutation plots.
Highly correlated genes for CPEB2:
Showing top 20/956 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CPEB2 | ACAA1 | 0.754775 | 5 | 0 | 5 |
| CPEB2 | ZNF212 | 0.753842 | 3 | 0 | 3 |
| CPEB2 | TANC1 | 0.752975 | 4 | 0 | 4 |
| CPEB2 | ACADSB | 0.744611 | 3 | 0 | 3 |
| CPEB2 | CLIP1 | 0.740832 | 8 | 0 | 8 |
| CPEB2 | SNX1 | 0.739587 | 3 | 0 | 3 |
| CPEB2 | FBXL3 | 0.728249 | 3 | 0 | 3 |
| CPEB2 | NAA35 | 0.719085 | 3 | 0 | 3 |
| CPEB2 | MRFAP1L1 | 0.716251 | 3 | 0 | 3 |
| CPEB2 | MTHFR | 0.716037 | 3 | 0 | 3 |
| CPEB2 | CWH43 | 0.715297 | 6 | 0 | 6 |
| CPEB2 | KLC1 | 0.71398 | 3 | 0 | 3 |
| CPEB2 | SUGT1 | 0.712201 | 4 | 0 | 4 |
| CPEB2 | APPL1 | 0.70863 | 4 | 0 | 3 |
| CPEB2 | SUCLA2 | 0.705178 | 5 | 0 | 5 |
| CPEB2 | LIN7B | 0.700612 | 3 | 0 | 3 |
| CPEB2 | SBF2 | 0.699676 | 3 | 0 | 3 |
| CPEB2 | MTF1 | 0.697502 | 4 | 0 | 4 |
| CPEB2 | KIAA2026 | 0.696919 | 3 | 0 | 3 |
| CPEB2 | MED28 | 0.695181 | 3 | 0 | 3 |
For details and further investigation, click here
