| Full name: mitochondrial translational initiation factor 3 | Alias Symbol: IF-3mt|IF3(mt) | ||
| Type: protein-coding gene | Cytoband: 13q12.2 | ||
| Entrez ID: 219402 | HGNC ID: HGNC:29788 | Ensembl Gene: ENSG00000122033 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of MTIF3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MTIF3 | 219402 | 223356_s_at | -0.5107 | 0.2588 | |
| GSE26886 | MTIF3 | 219402 | 223356_s_at | -0.1153 | 0.6619 | |
| GSE45670 | MTIF3 | 219402 | 223356_s_at | -0.2535 | 0.0613 | |
| GSE53622 | MTIF3 | 219402 | 10266 | -0.6867 | 0.0000 | |
| GSE53624 | MTIF3 | 219402 | 10266 | -0.5716 | 0.0000 | |
| GSE63941 | MTIF3 | 219402 | 223356_s_at | -0.9743 | 0.0357 | |
| GSE77861 | MTIF3 | 219402 | 223356_s_at | -0.6904 | 0.0030 | |
| GSE97050 | MTIF3 | 219402 | A_23_P53788 | -0.6891 | 0.0863 | |
| SRP007169 | MTIF3 | 219402 | RNAseq | -1.9005 | 0.0000 | |
| SRP008496 | MTIF3 | 219402 | RNAseq | -1.5096 | 0.0000 | |
| SRP064894 | MTIF3 | 219402 | RNAseq | -0.3258 | 0.1075 | |
| SRP133303 | MTIF3 | 219402 | RNAseq | -0.4481 | 0.0028 | |
| SRP159526 | MTIF3 | 219402 | RNAseq | -0.8887 | 0.0015 | |
| SRP193095 | MTIF3 | 219402 | RNAseq | -0.9775 | 0.0000 | |
| SRP219564 | MTIF3 | 219402 | RNAseq | -0.9089 | 0.0010 | |
| TCGA | MTIF3 | 219402 | RNAseq | -0.2472 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by MTIF3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MTIF3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MTIF3 | 219402 | 1 | 13 | 16 | |
| GSE20123 | MTIF3 | 219402 | 1 | 12 | 17 | |
| GSE43470 | MTIF3 | 219402 | 2 | 12 | 29 | |
| GSE46452 | MTIF3 | 219402 | 0 | 33 | 26 | |
| GSE47630 | MTIF3 | 219402 | 3 | 26 | 11 | |
| GSE54993 | MTIF3 | 219402 | 11 | 2 | 57 | |
| GSE54994 | MTIF3 | 219402 | 1 | 13 | 39 | |
| GSE60625 | MTIF3 | 219402 | 0 | 3 | 8 | |
| GSE74703 | MTIF3 | 219402 | 2 | 9 | 25 | |
| GSE74704 | MTIF3 | 219402 | 0 | 10 | 10 | |
| TCGA | MTIF3 | 219402 | 6 | 41 | 49 |
Total number of gains: 27; Total number of losses: 174; Total Number of normals: 287.
Somatic mutations of MTIF3:
Generating mutation plots.
Highly correlated genes for MTIF3:
Showing top 20/1197 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MTIF3 | DNAJA2 | 0.794305 | 3 | 0 | 3 |
| MTIF3 | GNG12 | 0.785295 | 3 | 0 | 3 |
| MTIF3 | TSPAN31 | 0.775501 | 3 | 0 | 3 |
| MTIF3 | CNR1 | 0.772114 | 3 | 0 | 3 |
| MTIF3 | RHBDF1 | 0.762333 | 3 | 0 | 3 |
| MTIF3 | SAP18 | 0.761684 | 6 | 0 | 6 |
| MTIF3 | TMEM219 | 0.75768 | 6 | 0 | 6 |
| MTIF3 | PITHD1 | 0.75545 | 4 | 0 | 4 |
| MTIF3 | NFIA | 0.749595 | 6 | 0 | 6 |
| MTIF3 | GPR108 | 0.748283 | 3 | 0 | 3 |
| MTIF3 | ACADVL | 0.744998 | 5 | 0 | 5 |
| MTIF3 | SYTL4 | 0.738326 | 3 | 0 | 3 |
| MTIF3 | JAK2 | 0.735876 | 5 | 0 | 5 |
| MTIF3 | GPD1L | 0.733786 | 6 | 0 | 6 |
| MTIF3 | GALNT12 | 0.732053 | 5 | 0 | 5 |
| MTIF3 | RAD17 | 0.731302 | 3 | 0 | 3 |
| MTIF3 | ITPR1 | 0.730971 | 3 | 0 | 3 |
| MTIF3 | NR2F6 | 0.72983 | 3 | 0 | 3 |
| MTIF3 | MAP1A | 0.728954 | 3 | 0 | 3 |
| MTIF3 | ZFP36L2 | 0.728325 | 3 | 0 | 3 |
For details and further investigation, click here
