| Full name: general transcription factor IIIC subunit 6 | Alias Symbol: bA397G5.3|TFIIIC35 | ||
| Type: protein-coding gene | Cytoband: 6q21 | ||
| Entrez ID: 112495 | HGNC ID: HGNC:20872 | Ensembl Gene: ENSG00000155115 | OMIM ID: 611784 |
| Drug and gene relationship at DGIdb | |||
Expression of GTF3C6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GTF3C6 | 112495 | 225083_at | -0.2932 | 0.3968 | |
| GSE26886 | GTF3C6 | 112495 | 225083_at | -0.4862 | 0.0119 | |
| GSE45670 | GTF3C6 | 112495 | 225083_at | 0.1612 | 0.1332 | |
| GSE53622 | GTF3C6 | 112495 | 3890 | -0.1025 | 0.1357 | |
| GSE53624 | GTF3C6 | 112495 | 55458 | -0.1323 | 0.0108 | |
| GSE63941 | GTF3C6 | 112495 | 225083_at | -0.4200 | 0.5116 | |
| GSE77861 | GTF3C6 | 112495 | 225083_at | -0.1584 | 0.4420 | |
| GSE97050 | GTF3C6 | 112495 | A_23_P400465 | 0.0165 | 0.9646 | |
| SRP007169 | GTF3C6 | 112495 | RNAseq | -0.0276 | 0.9696 | |
| SRP064894 | GTF3C6 | 112495 | RNAseq | 0.2691 | 0.2450 | |
| SRP133303 | GTF3C6 | 112495 | RNAseq | 0.3379 | 0.0412 | |
| SRP159526 | GTF3C6 | 112495 | RNAseq | -0.1044 | 0.6539 | |
| SRP193095 | GTF3C6 | 112495 | RNAseq | -0.4162 | 0.0014 | |
| SRP219564 | GTF3C6 | 112495 | RNAseq | -0.0107 | 0.9776 | |
| TCGA | GTF3C6 | 112495 | RNAseq | -0.0289 | 0.6259 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GTF3C6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GTF3C6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GTF3C6 | 112495 | 2 | 3 | 25 | |
| GSE20123 | GTF3C6 | 112495 | 2 | 3 | 25 | |
| GSE43470 | GTF3C6 | 112495 | 3 | 1 | 39 | |
| GSE46452 | GTF3C6 | 112495 | 2 | 11 | 46 | |
| GSE47630 | GTF3C6 | 112495 | 9 | 4 | 27 | |
| GSE54993 | GTF3C6 | 112495 | 3 | 2 | 65 | |
| GSE54994 | GTF3C6 | 112495 | 8 | 8 | 37 | |
| GSE60625 | GTF3C6 | 112495 | 0 | 2 | 9 | |
| GSE74703 | GTF3C6 | 112495 | 2 | 1 | 33 | |
| GSE74704 | GTF3C6 | 112495 | 0 | 1 | 19 | |
| TCGA | GTF3C6 | 112495 | 6 | 23 | 67 |
Total number of gains: 37; Total number of losses: 59; Total Number of normals: 392.
Somatic mutations of GTF3C6:
Generating mutation plots.
Highly correlated genes for GTF3C6:
Showing top 20/290 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GTF3C6 | ELK3 | 0.79976 | 3 | 0 | 3 |
| GTF3C6 | SOX7 | 0.776549 | 3 | 0 | 3 |
| GTF3C6 | PPP4R1 | 0.770732 | 3 | 0 | 3 |
| GTF3C6 | ARG2 | 0.763941 | 3 | 0 | 3 |
| GTF3C6 | PPP6C | 0.751651 | 3 | 0 | 3 |
| GTF3C6 | GOLGA4 | 0.745961 | 3 | 0 | 3 |
| GTF3C6 | NDUFB8 | 0.745607 | 3 | 0 | 3 |
| GTF3C6 | ITPR2 | 0.745293 | 3 | 0 | 3 |
| GTF3C6 | PSMC5 | 0.74227 | 3 | 0 | 3 |
| GTF3C6 | OSBPL10 | 0.739693 | 3 | 0 | 3 |
| GTF3C6 | ZNF426 | 0.737884 | 3 | 0 | 3 |
| GTF3C6 | BDKRB2 | 0.737332 | 3 | 0 | 3 |
| GTF3C6 | AK4 | 0.735513 | 4 | 0 | 4 |
| GTF3C6 | CXXC5 | 0.732944 | 3 | 0 | 3 |
| GTF3C6 | LDHA | 0.731022 | 3 | 0 | 3 |
| GTF3C6 | IMPDH2 | 0.730655 | 4 | 0 | 4 |
| GTF3C6 | DUSP18 | 0.729681 | 3 | 0 | 3 |
| GTF3C6 | PDHB | 0.729167 | 4 | 0 | 3 |
| GTF3C6 | NHLH2 | 0.727338 | 3 | 0 | 3 |
| GTF3C6 | ADCY7 | 0.7248 | 3 | 0 | 3 |
For details and further investigation, click here
