| Full name: SRY-box transcription factor 7 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 8p23.1 | ||
| Entrez ID: 83595 | HGNC ID: HGNC:18196 | Ensembl Gene: ENSG00000171056 | OMIM ID: 612202 |
| Drug and gene relationship at DGIdb | |||
Expression of SOX7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SOX7 | 83595 | 228698_at | -0.8029 | 0.3467 | |
| GSE26886 | SOX7 | 83595 | 228698_at | -0.5525 | 0.2486 | |
| GSE45670 | SOX7 | 83595 | 228698_at | 0.1429 | 0.6389 | |
| GSE53622 | SOX7 | 83595 | 46387 | -0.4388 | 0.0014 | |
| GSE53624 | SOX7 | 83595 | 46387 | -0.8143 | 0.0000 | |
| GSE63941 | SOX7 | 83595 | 228698_at | 4.3407 | 0.0380 | |
| GSE77861 | SOX7 | 83595 | 228698_at | -0.2386 | 0.6351 | |
| GSE97050 | SOX7 | 83595 | A_23_P306987 | 0.2701 | 0.5534 | |
| SRP007169 | SOX7 | 83595 | RNAseq | 0.6724 | 0.3816 | |
| SRP064894 | SOX7 | 83595 | RNAseq | -0.4367 | 0.1855 | |
| SRP133303 | SOX7 | 83595 | RNAseq | -0.8752 | 0.0107 | |
| SRP159526 | SOX7 | 83595 | RNAseq | -1.5419 | 0.0015 | |
| SRP193095 | SOX7 | 83595 | RNAseq | -0.3102 | 0.2943 | |
| SRP219564 | SOX7 | 83595 | RNAseq | -0.4947 | 0.2166 | |
| TCGA | SOX7 | 83595 | RNAseq | 0.4157 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by SOX7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SOX7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SOX7 | 83595 | 4 | 11 | 15 | |
| GSE20123 | SOX7 | 83595 | 4 | 11 | 15 | |
| GSE43470 | SOX7 | 83595 | 4 | 9 | 30 | |
| GSE46452 | SOX7 | 83595 | 12 | 14 | 33 | |
| GSE47630 | SOX7 | 83595 | 10 | 7 | 23 | |
| GSE54993 | SOX7 | 83595 | 3 | 14 | 53 | |
| GSE54994 | SOX7 | 83595 | 9 | 19 | 25 | |
| GSE60625 | SOX7 | 83595 | 3 | 0 | 8 | |
| GSE74703 | SOX7 | 83595 | 4 | 7 | 25 | |
| GSE74704 | SOX7 | 83595 | 3 | 7 | 10 | |
| TCGA | SOX7 | 83595 | 14 | 39 | 43 |
Total number of gains: 70; Total number of losses: 138; Total Number of normals: 280.
Somatic mutations of SOX7:
Generating mutation plots.
Highly correlated genes for SOX7:
Showing top 20/223 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SOX7 | UBE2B | 0.785921 | 3 | 0 | 3 |
| SOX7 | ST5 | 0.777802 | 3 | 0 | 3 |
| SOX7 | GTF3C6 | 0.776549 | 3 | 0 | 3 |
| SOX7 | VDAC3 | 0.748957 | 3 | 0 | 3 |
| SOX7 | TMCO6 | 0.723314 | 3 | 0 | 3 |
| SOX7 | DSE | 0.719353 | 3 | 0 | 3 |
| SOX7 | REEP3 | 0.704558 | 3 | 0 | 3 |
| SOX7 | TINAGL1 | 0.69701 | 3 | 0 | 3 |
| SOX7 | RRAD | 0.693343 | 4 | 0 | 3 |
| SOX7 | FAM114A2 | 0.688103 | 4 | 0 | 3 |
| SOX7 | ALDOC | 0.68629 | 3 | 0 | 3 |
| SOX7 | UBE2D2 | 0.684364 | 4 | 0 | 3 |
| SOX7 | SFN | 0.681599 | 4 | 0 | 4 |
| SOX7 | SGPP1 | 0.679435 | 3 | 0 | 3 |
| SOX7 | LDHD | 0.679007 | 3 | 0 | 3 |
| SOX7 | FAM204A | 0.677697 | 3 | 0 | 3 |
| SOX7 | MPV17L | 0.675538 | 3 | 0 | 3 |
| SOX7 | PGM1 | 0.674953 | 4 | 0 | 3 |
| SOX7 | PPP1R3B | 0.674905 | 4 | 0 | 3 |
| SOX7 | MBOAT2 | 0.674687 | 4 | 0 | 3 |
For details and further investigation, click here
