| Full name: ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 | Alias Symbol: ST6GALNACVI | ||
| Type: protein-coding gene | Cytoband: 9q34.11 | ||
| Entrez ID: 30815 | HGNC ID: HGNC:23364 | Ensembl Gene: ENSG00000160408 | OMIM ID: 610135 |
| Drug and gene relationship at DGIdb | |||
Expression of ST6GALNAC6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ST6GALNAC6 | 30815 | 222571_at | -0.2714 | 0.3121 | |
| GSE26886 | ST6GALNAC6 | 30815 | 222571_at | 0.1659 | 0.3357 | |
| GSE45670 | ST6GALNAC6 | 30815 | 222571_at | -0.5112 | 0.0000 | |
| GSE53622 | ST6GALNAC6 | 30815 | 84195 | -0.7662 | 0.0000 | |
| GSE53624 | ST6GALNAC6 | 30815 | 84195 | -0.7130 | 0.0000 | |
| GSE63941 | ST6GALNAC6 | 30815 | 222571_at | -1.5747 | 0.0002 | |
| GSE77861 | ST6GALNAC6 | 30815 | 222571_at | -0.1658 | 0.3541 | |
| GSE97050 | ST6GALNAC6 | 30815 | A_23_P315892 | -0.4906 | 0.1406 | |
| SRP007169 | ST6GALNAC6 | 30815 | RNAseq | -1.9403 | 0.0000 | |
| SRP008496 | ST6GALNAC6 | 30815 | RNAseq | -1.6279 | 0.0000 | |
| SRP064894 | ST6GALNAC6 | 30815 | RNAseq | -0.0779 | 0.8242 | |
| SRP133303 | ST6GALNAC6 | 30815 | RNAseq | -0.4824 | 0.0795 | |
| SRP159526 | ST6GALNAC6 | 30815 | RNAseq | -0.7875 | 0.0000 | |
| SRP193095 | ST6GALNAC6 | 30815 | RNAseq | -0.4487 | 0.0004 | |
| SRP219564 | ST6GALNAC6 | 30815 | RNAseq | -0.6784 | 0.1994 | |
| TCGA | ST6GALNAC6 | 30815 | RNAseq | -0.2600 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by ST6GALNAC6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ST6GALNAC6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ST6GALNAC6 | 30815 | 6 | 9 | 15 | |
| GSE20123 | ST6GALNAC6 | 30815 | 6 | 9 | 15 | |
| GSE43470 | ST6GALNAC6 | 30815 | 5 | 7 | 31 | |
| GSE46452 | ST6GALNAC6 | 30815 | 6 | 13 | 40 | |
| GSE47630 | ST6GALNAC6 | 30815 | 3 | 16 | 21 | |
| GSE54993 | ST6GALNAC6 | 30815 | 3 | 3 | 64 | |
| GSE54994 | ST6GALNAC6 | 30815 | 11 | 8 | 34 | |
| GSE60625 | ST6GALNAC6 | 30815 | 0 | 0 | 11 | |
| GSE74703 | ST6GALNAC6 | 30815 | 5 | 5 | 26 | |
| GSE74704 | ST6GALNAC6 | 30815 | 3 | 7 | 10 | |
| TCGA | ST6GALNAC6 | 30815 | 27 | 25 | 44 |
Total number of gains: 75; Total number of losses: 102; Total Number of normals: 311.
Somatic mutations of ST6GALNAC6:
Generating mutation plots.
Highly correlated genes for ST6GALNAC6:
Showing top 20/1094 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ST6GALNAC6 | AFF3 | 0.83083 | 3 | 0 | 3 |
| ST6GALNAC6 | C11orf96 | 0.828829 | 3 | 0 | 3 |
| ST6GALNAC6 | KDM5D | 0.79862 | 3 | 0 | 3 |
| ST6GALNAC6 | USP9Y | 0.792912 | 3 | 0 | 3 |
| ST6GALNAC6 | GRHPR | 0.791838 | 3 | 0 | 3 |
| ST6GALNAC6 | ZNF407 | 0.79106 | 3 | 0 | 3 |
| ST6GALNAC6 | PIGP | 0.785358 | 3 | 0 | 3 |
| ST6GALNAC6 | USP33 | 0.784671 | 3 | 0 | 3 |
| ST6GALNAC6 | ZBTB10 | 0.783552 | 3 | 0 | 3 |
| ST6GALNAC6 | IP6K1 | 0.782807 | 3 | 0 | 3 |
| ST6GALNAC6 | TMEM140 | 0.766981 | 3 | 0 | 3 |
| ST6GALNAC6 | NPY1R | 0.765866 | 3 | 0 | 3 |
| ST6GALNAC6 | FIBIN | 0.765007 | 4 | 0 | 4 |
| ST6GALNAC6 | NLGN4Y | 0.764147 | 3 | 0 | 3 |
| ST6GALNAC6 | PDCD4 | 0.762494 | 4 | 0 | 4 |
| ST6GALNAC6 | BSN | 0.760776 | 3 | 0 | 3 |
| ST6GALNAC6 | CLEC3B | 0.756897 | 3 | 0 | 3 |
| ST6GALNAC6 | EIF1AY | 0.753805 | 3 | 0 | 3 |
| ST6GALNAC6 | MCAM | 0.752813 | 3 | 0 | 3 |
| ST6GALNAC6 | ATP9B | 0.749061 | 4 | 0 | 4 |
For details and further investigation, click here
